Poster Hall: MALDI Imaging and SpatialOMx

Poster Hall MALDI Imaging

Poster Hall MALDI Imaging and SpatialOMx

Bruker’s MALDI Imaging systems are impacting a wide range of research fields. Inside this poster hall we present a selection of recent scientific presentations that employ MALDI Imaging or SpatialOMx to answer a variety of biological questions. Please browse the posters to see how the versatility of MALDI Imaging may help you overcome research challenges.

We are grateful to the authors for allowing their posters to be included.

Poster Hall MALDI Imaging

Cancer

Poster IMSC 2022: Multiomic analysis of hepatocellular carcinoma using MALDI Imaging Mass Spectrometry

Poster ASMS 2022: Oncogene induced shifts in metabolic flux of bi-clonal tumours as revealed by stable isotope labeling and mass spectrometry imaging (MSI) analysis

Customer Poster ASMS 2022: Mass spectrometry imaging of the metabolic landscape of human papillomavirus-associated versus carcinogen-driven head and neck squamous cell carcinoma

Customer Poster ASMS 2022: Spatially Resolved Lipidomic Profiling of Ovarian Cancer Using Ultrahigh Resolution Mass Spectrometry Imaging

Poster 2020: MALDI Mass Spectrometry Imaging of Gemcitabine Treatment in Pancreatic Cancer: Exploring Multiple Matrices to see the whole Picture

Poster 2020: Comparative N-glycome analysis of prostate cancer tissues using MALDI Q-TOF versus MALDI-FTICR imaging mass spectrometry workflows

Poster 2020: A novel and promising proteomic-based MALDI-MSI thyroid nodule classifier as complementary diagnostic tool in cytopathology

Poster 2020: Molecular characterization of NAFLD-related liver cancer in pig using MALDI imaging mass spectrometry and shotgun proteomics

Poster 2019: Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction

Poster 2019: MALDI-MSI analysis enables a spatially resolved characterisation of the proteome and metabolome in radiotherapy treated HNSCC 

Poster 2019: Multimodal FTIR Microscopy-guided MALDI Mass Spectrometry Imaging for Tumor Analysis 

Poster 2019: Quantitative Mass Spectrometry Imaging Reveals Mutation Status-independent Lack of Imatinib Penetration in Liver Metastases of Gastrointestinal Stromal Tumors 

Poster 2019: Optimized data analysis pipeline for MALDI MSI based tumor typing from FFPE tissue samples evaluated on six benchmark classification tasks

Poster 2019: Predicting Lymph Node Metastasis in Endometrial Cancer by multi-modal mass spectrometry imaging 

Poster 2018: A novel imaging mass spectrometry method for visualizing chemical communication in metastasis

Poster 2018: N-Linked Glycan Branching and Fucosylation are Increased Directly in HCC Tissue as Determined Through in situ Glycan Imaging 

Poster 2018: Site-to-site reproducibility of Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging from Formalin-Fixed Paraffin-Embedded samples 

Poster 2018: Altered metabolism in prostate cancer and stroma detected through MALDI-TOF MSI 

Poster 2018: Combining Mass Spectrometry Imaging and top-down proteomics to predict immunotherapy response in non-small-cell lung cancer patients 

Poster 2018: Discrimination of normal oral mucosa from oral cancer by mass spectrometry imaging of proteins and lipids

Clinical

Poster IMSC 2022: MALDI Imaging lipid analysis integrated with histological data for a complete spatial contextual evaluation

Poster ASMS 2022: MALDI Imaging lipid analysis integrated with histological data for a complete spatial-contextual evaluation

Customer Poster ASMS 2022: Investigation of Sulfur Scavenging In a Mouse Model of Systemic Staphylococcus aureus Infection Using Imaging Mass Spectrometry

Customer Poster ASMS 2022: Classification of cirrhotic patient samples based on imaging MS of multiplexed N-glycan markers in biofluids

Customer Poster ASMS 2022: Distinguishing transthyretin marker peptides from amyloidosis model tissue using MALDI

Poster 2019: Imaging mass spectrometry analysis enables in-situ detection of human papillomavirus in FFPE tissues

Poster 2019: Unraveling pathogenesis of dilated cardiomyopathy (DCM) on J2N-k Hamster model using MALDI-Imaging Mass Spectrometry in combination with shotgun proteomics

Poster 2019: Reproducibility of MALDI Imaging Based Tissue Classifications Results of a Multi Center Study

Poster 2018: Comparative 2D N-glycome, stromal peptide, and tryptic peptide mapping from the same FFPE Tissue Section using MALDI Imaging Mass Spectrometry

Poster 2018: Site-to-site reproducibility of Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging from Formalin-Fixed Paraffin-Embedded samples

Poster 2018: Method optimization for on-tissue tryptic digestion of formalin-fixed paraffin-embedded human thyroid tissues for MALDI imaging MS

Glycans

Poster IMSC 2022: Multiomic analysis of hepatocellular carcinoma using MALDI Imaging Mass Spectrometry

Poster ASMS 2022: Sequential MALDI-MS imaging of lipids, N-Glycans, and tryptic peptides on a single FFPE tissue section

Customer Poster ASMS 2022: Establishment of the Full Glycan and Collagen Biomarker Profile for Prostate Cancer Tissue Samples Representing a Broad Spectrum of Histopathologies Using MALDI-IMS

Customer Poster ASMS 2022: Imaging mass spectrometry reveals sialylated glycans and activated lymphocytes in non-alcoholic steatohepatitis

Customer Poster ASMS 2022: Characterizing the Glycan and Collagen Biomarker Profiles of DCIS

Customer Poster ASMS 2022: Defining a Human N-glycome Tissue Atlas of the Colon Adenoma to Adenocarcinoma Sequence by N-glycan MALDI-IMS

Customer Poster ASMS 2022: Metabolic Imaging of O-linked N-Acetylglucosamine using On-Tissue Hydrolysis and MALDI

Customer Poster ASMS 2022: Antibody Array Based N-glycan Imaging of Captured Immune Cells

Poster ASMS 2021: N-glycosylation of hepatocellular carcinoma correlates with genetic subtypes

Poster 2020: Comparative N-glycome analysis of prostate cancer tissues using MALDI Q-TOF versus MALDI-FTICR imaging mass spectrometry workflows

Poster 2020: Laser-induced post-ionization coupled to a timsTOF fleX for the enhanced MALDI-2-MS analysis of N-glycans 

Poster 2019: Fully automated mass alignment and recalibration of MALDI TOF imaging data from N-linked glycans

Poster 2019: Different MALDI Mass Spectrometry Imaging Applications on a Prototype MALDI Q TOF Instrument

Poster 2018: Comparative 2D N-glycome, stromal peptide, and tryptic peptide mapping from the same FFPE Tissue Section using MALDI Imaging Mass Spectrometry

Poster 2018: N-Linked Glycan Branching and Fucosylation are Increased Directly in HCC Tissue as Determined Through in situ Glycan Imaging

Lipids

Poster ASMS 2022: A sample stage design for MALDI Imaging with adaptive laser optics improves positioning accuracy for high resolution imaging

Customer Poster ASMS 2022: Quantitative Mass Spectrometry Imaging to Study Lipid Metabolism in Parkinson’s Disease Model

Customer Poster ASMS 2022: Lipidome Alterations in Mild Traumatic Brain Injury Mapped via FTICR Mass Spectrometry Imaging

Customer Poster ASMS 2022: Novel mass tags for the sensitive detection of steroidal ketones by MALDI MSI

Customer Poster ASMS 2022: Imaging interspecies interactions in bacterial co-cultures using nanostructured DIUTHAME membranes in laser desorption/ionization mass spectrometry

Poster ASMS 2021: The SCiLS autopilot – a new workflow facilitating MALDI Imaging measurement set-ups

Poster ASMS 2021: A combination of single-cell MALDI-MS imaging and fluorescence microscopy to explore molecular heterogeneity in cell cultures

Poster ASMS 2021: Mixed nanoparticle matrix materials for mass spectrometry imaging of small molecules and lipids

Poster ASMS 2021: MALDI imaging analysis of the canine heartworm, Dirofilaria immitis using a timsTOF fleX 

Poster 2020: MALDI-2 laser post-ionization on a trapped ion mobility orthogonal time of flight instrument

Poster 2020: In situ isobaric and isomeric lipid mapping and identification by MALDI-Ion Mobility Separation-Mass Spectrometry Imaging

Poster 2020: 4D-Lipidomics based automated annotation of MALDI Imaging data using a dedicated bioinformatics pipeline

Poster 2020: Advanced Biomarker Discovery in Imaging Mass Spectrometry Through Interpretable Supervised Machine Learning 

Poster 2020: Preserved and variable spatial-chemical changes of lipids across leaves in response to wounding

Poster 2020: Automated feature finding and evaluation of m/z images based on CCS separation in MALDI TIMS imaging data

Poster 2020: Quality assessment of MALDI TOF and ion mobility MSI data based on mass defect and CCS filtering

Poster 2020: Advanced Methods for Differentiating Lipid Isomers in Tissue using Trapped Ion Mobility Imaging Mass Spectrometry

Poster 2020: DIUTHAME enables matrix-free mass spectrometry imaging of frozen tissue sections of Alzheimer’s disease (AD) brain

Poster 2020: Minimizing Visceral Fat Delocalization on Tissue Sections with Porous Aluminum Oxide Slides for ImagingMass Spectrometry

Poster 2019: Automatic molecular annotation of mass spectrometry imaging data

Poster 2019: High Speed, High Lateral Resolution Lipid Imaging in a MALDI-Q-TOF

Poster 2018: Applications of 1,5-diaminonaphthalene for MALDI imaging of lipids in neurodegenerative disorders

Poster 2018: Altered metabolism in prostate cancer and stroma detected through MALDI-TOF MSI

Poster 2018: Combining MALDI Imaging and Liquid Surface Extraction for Spatial Metabolomics

Poster 2018: Discrimination of normal oral mucosa from oral cancer by mass spectrometry imaging of proteins and lipids

Pharma

Poster IMSC 2022: microGRID Technology For Robust High-resolution Imaging Down To The (Sub)cellular Level

Poster ASMS 2021: Zebrafish larvae as toxicity model for drug development using imaging mass spectrometry

Poster 2020: Visualization of Intact protein for the study of lithium neuropharmacology in mouse brain with MALDI - Imaging Mass Spectroscopy

Poster 2020: Laser post ionization (MALDI-2) coupled to a timsTOF fleX improves limits of detection for statin drug compounds in MALDI-MS imaging

Poster 2020: MALDI Mass Spectrometry Imaging of Gemcitabine Treatment in Pancreatic Cancer: Exploring Multiple Matrices to See the Whole Picture

Poster 2019: Rapid identification of chemically-related compounds produced by bacteria by Kendrick mass defect filtering applied to high resolution imaging mass spectrometry

Poster 2019: Study of Perifosine Penetration in 3D Cell Cultures using Peeling Analysis of MALDI MS and Immunofluorescent Images

Poster 2019: Quantitative Mass Spectrometry Imaging Reveals Mutation Status-independent Lack of Imatinib Penetration in Liver Metastases of Gastrointestinal Stromal Tumors

Poster 2018: A Multi-Center Validation Study of Quantitative Imaging Mass Spectrometry

Poster 2018: An Investigation into Retigabine (Ezogabine) Associated Dyspigmentation in Rat Eye by MALDI Imaging Mass Spectrometry (IMS)

Poster 2018: Visualizing the Pharmacology of a Diglyceride-acyltransferase (DGAT) Inhibitor in Skin after Oral Dosing by MALDI Imaging Mass Spectrometry: from Pre-clinical to Clinical

Proteins

Poster ASMS 2022: Precision proteomics for the characterization of follicular-patterned thyroid neoplasms entities

Poster ASMS 2022: MALDI HiPLEX-IHC: Highly Multiplex & Multiomic Tissue Imaging with Photocleavable Mass-Tagged Probes

Customer Poster ASMS 2022: Intact Protein MALDI Mass Spectrometry Imaging (MSI) to characterize target engagement and blood-brain barrier penetration for amyotrophic lateral sclerosis (ALS)

Customer Poster ASMS 2022: Mass Spectrometry Imaging for Protein Localization and Characterization in Thermoembolized Hepatic Porcine Tissue

Poster 2020: In depth proteomics of the kidneys from autoimmune type I diabetes rat model through MALDI - Imaging Mass Spectrometry

Poster 2020: A novel and promising proteomic-based MALDI-MSI thyroid nodule classifier as complementary diagnostic tool in cytopathology

Poster 2020: Identification of Therapeutic Targets of Multiple Sclerosis through MALDI - Imaging Mass Spectrometry of Experimental Autoimmune Encephalomyelitis (EAE) mouse model

Poster 2020: Unraveling pathogenesis of dilated cardiomyopathy (DCM) on J2N-k Hamster model using MALDI-Imaging Mass Spectrometry in combination with shotgun proteomics

Poster 2020: In depth Proteomics of Hair Follicles of whiskers from W mutant mice clarifies KIT restriction on hematopoiesis and melanogenesis

Poster 2019: Fast and Sensitive Quantitative Proteomic Analysis of Formalin-Fixed Paraffin-Embedded Tissue Using a Trapped Ion Mobility Q-TOF

Poster 2019: Mass Spectrometric In-Depth Proteome Analysis of the Kidneys from Rat Model of Diabetic Nephropathy

Poster 2019: Unraveling pathogenesis of dilated cardiomyopathy (DCM) on J2N-k Hamster model using MALDI-Imaging Mass Spectrometry in combination with shotgun proteomics

Poster 2018: Combining Mass Spectrometry Imaging and Top Down Proteomics to Predict Immunotherapy Response in Non-Small Cell Lung Cancer Patients

Poster 2018: Discrimination of Normal Oral Mucosa from Oral Cancer by Mass Spectrometry Imaging Of Proteins and Lipids

Poster 2018: Method optimization for on tissue tryptic digestion of formalin fixed paraffin embedded human thyroid tissues for MALDI Imaging M

SpatialOMx

Poster IMSC 2022: Host-Microbe Interaction: SpatialOMx as Key Technology to Gain Insight into Bacteria Localization and Function in Mussel Gills

Poster IMSC 2022: SpatialOMx at its Best: Comparison of different Staining Procedures and Slide Types

Poster ASMS 2022: In situ murine thymic proteomics by using MALDI Imaging Mass Spectrometry in combination with shotgun LC-MS/MS

Poster ASMS 2022: Multi-omics strategy for the studies of immune regulation in pluripotent stem cell-based cardiac regenerative medicine in a swine model

Poster ASMS 2022: Microbe visualization and phenotype identification of mussel gills using SpatialOMx

Poster ASMS 2022: Exploring human brain proteome of Alzheimer’s disease (AD) using MALDI Imaging Mass Spectrometry in combination with lipidomics in situ

Customer Poster ASMS 2022: Multiomic Analyses of Pancreatic Islets via Laser Capture Microdissection-Mass Spectrometry and timsTOF fleX MALDI-2 Imaging

Poster ASMS 2021: CCS-Enabled SpatialOMx® for automatic annotation of lipids in MALDI Images based on 4D-Lipidomics data

Poster ASMS 2021: Bringing Physiological Content to Omics Studies by Optimizing the Pixel to Chromatogram Connection through Spatialomx

Poster 2020: In situ isobaric and isomeric lipid mapping and identification by MALDI-Ion Mobility Separation-Mass Spectrometry Imaging

Poster 2020: 4D-Lipidomics based automated annotation of MALDI Imaging data using a dedicated bioinformatics pipeline

Poster 2020: In depth proteomics of the kidneys from autoimmune type I diabetes rat model through MALDI - Imaging Mass Spectrometry

Poster 2020: Unraveling pathogenesis of dilated cardiomyopathy (DCM) on J2N-k Hamster model using MALDI-Imaging Mass Spectrometry in combination with shotgun proteomics

Poster 2020: Molecular characterization of NAFLD-related liver cancer in pig using MALDI imaging mass spectrometry and shotgun proteomics

Poster 2020: Molecular dissection of renal amyloidosis with MALDI - Imaging Mass Spectrometry and shotgun proteomics on paraffin embedded biopsy tissue section

Poster 2020: Exploring in depth brain proteome of Alzheimer's disease (AD) with MALDI Imaging Mass Spectrometry in combination with shotgun proteomics

Poster 2020: Advanced Methods for Differentiating Lipid Isomers in Tissue using Trapped Ion Mobility Imaging Mass Spectrometry

Poster 2019: MALDI mass spectrometry imaging guided LC-MS on the same instrument

Poster 2019: Characteristics of MALDI-imaging on a new dual ion source QTOF with TIMS separation

Poster 2019: Combining MALDI Imaging and Liquid Surface Extraction for Spatial Metabolomics

Poster 2019: Different MALDI Mass Spectrometry Imaging Applications on a Prototype MALDI Q TOF Instrument

 

For Research Use Only. Not for use in clinical diagnostic procedures.