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PANIC 2023

PANIC 2023 Content Download

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Why Infer when we can be sure?

For more than 60 years, Bruker has enabled scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. Bruker’s high-performance analytical and diagnostic systems explore life and materials at molecular, cellular and microscopic levels in the applied, molecular, and pharmaceutical research areas.

Thank you for joining us at the 2023 PANIC Annual Meeting. This page provides access to our latest NMR advancements and literature downloads.

Have a question? Connect with our Team!


 

From the Cover

Efficient analysis of pharmaceutical drug substances and products using a solid-state NMR CryoProbe

5-to-6-fold sensitivity enhancement enables characterization of drug–drug and drug–polymer interactions in amorphous posaconazole and its amorphous solid dispersion formulation. This is the first illustration of the CPMAS CryoProbe for the characterization of drug product. 13C and 15N detections and even 2D 13C-13C (INADEQUATE) are now possible on formulated samples! Congratulations to the scientists at Merck & Co and the Bruker team!

Discover our Solutions

Biotherapeutics Characterization Hub

Discover our virtual hub Advancing Biotherapeutics Characterization with Magnetic Resonance: on one page you can easily access webinars and articles from pharma key opinion leaders and find new solutions for the quality assessment of biologics and biosimilars at atomic resolution.

Solid State NMR

Solid State Analysis of Medicines with Enhanced Productivity

The new CPMAS CryoProbe reduces drug product measurement time by one order of magnitude and enables structural elucidation experiments not possible before. Structure-property relationship for rational drug development, with confidence!

      

Although traditionally in the hands of few specialists, recent advances in solid-state NMR have enabled the deployment of the technique to the walk-up lab. Instruments are today equipped with the new iProbe with automatic tuning and matching and magic angle adjustment; and sample changers driven by the same automation software used in liquid state NMR. Because of the new ‘shuttle technology’ the same sample changer can be used for both liquids and solids NNR, which enables to upgrade from liquids to solids for half the price of a Powder X-ray Diffraction (PXRD) instrument.

Polymorphs

Benchtop NMR

Need to improve process control? Tired of repetitive and time-consuming calibrations?
Flow NMR is now at your fingertips with our new benchtop solution for online monitoring of chemical and bio processes by NMR, in real-time, under real process conditions.

Bruker’s Fourier RxnLab provides answers to key chemical questions, such as conversion, in-situ reaction yield and reaction kinetics.
Provides answers to key chemical questions: reaction yield, mechanistic insights and reaction kinetics Harness NMR data to make strategic process chemistry decisions, ultimately leading to cost savings.

Process Analytical Technologies

PAT offers the pharmaceutical industry a framework for revolutionizing its R&D and manufacturing businesses, to produce value for both themselves and patients. The main benefits associated with PAT for companies include:

  • Reduced waste, right-first-time manufacturing, higher production asset utilization
  • Real-time quality assurance and validation
  • Increased movement toward a real-time product release
  • Reduced raw material, work-in-progress, and finished goods inventories by lean manufacturing processes
  • Increased robust product supply to the public 

Interconnected Lab

Straight from the lab, this animated clip showcases our cast of characters working to create an effective and efficient lab.

Lab connectivity Lab Tales | Bruker

Additional Resources for Clinical Research and Nutrition

Discover how NMR*-Based Metabolomic Solutions may help researchers in precision medicine and personalized nutrition discoveries.

*Bruker NMR Instruments are for Research Use Only. Not for Use in Clinical Diagnostic Procedures.

Additional Resources for Food Analysis

Bruker has tailored Nuclear Magnetic Resonance (NMR) specifically for the analysis of food to ensure your product’s quality and authenticity.