PET Image Reconstruction Overview - Current and Future Trends

Image reconstruction is a fundamental part of PET allowing to generate 3D tomographic images of the tracer’s spatial distribution based on the position and timing of the detected annihilation gammas. PET reconstruction, common to other imaging modalities like CT and SPECT, apply algorithms whose mathematical details the general users may not need to understand. Nevertheless, a good knowledge on the performance characteristics of different algorithms can be highly beneficial to obtain reliable quantitative images more efficiently.

This webinar will be a guided tour to PET image reconstruction for the application-oriented user making sense of the sometimes complex reconstruction concepts. The webinar will cover the Pros & Cons and FAQs of PET image reconstruction, from analytical (FBP) to iterative methods (MLEM, OSEM and MAP), from the importance of physical corrections (scatter, attenuation etc) to reconstruction acceleration and noise reduction. In addition, the webinar will give you a glimpse of what to expect in the future with exciting insights into topics like how MRI can make better PET images and how AI can be applied to PET reconstruction.

This webinar took place on May 21st, 2020

Who to Expect

During the first part of the webinar Dr. Josep Oliver will provide an overview all the basic concepts of PET image reconstruction. Josep will cover iterative and analytical algorithms discussing their fundamentals, as well as, their advantages and disadvantages and recommended settings. Key concepts like resolution, noise, artifacts and convergence will be explained in a manner that allows the application-oriented user to understand the impact of reconstruction parameters on quantification and image quality. In the second part, Dr Harry Tsoumpas will discuss the importance of data corrections as part of image reconstruction and then will proceed with an outlook to exciting new PET image reconstruction opportunities arising from the availability of hybrid imaging devices combined with current trends in computer science. Josep and Harry will be available at the end to take questions from the audience.

Key Topics

Fundamentals of FBP

  • Basic model and concepts
  • Pros & Cons


Fundamentals of MLEM

  • Basic model and concepts
  • Pros & Cons


Improvements to MLEM

  • Accelerating the reconstruction
  • Reducing noise




The importance of data corrections in image reconstruction

  • Motion correction
  • Attenuation & scatter correction
  • Correction of other effects


Image reconstruction for quantification

  • Dynamic imaging
  • Kinetic modelling


Current and future trends

  • The role of MRI in improving PET images
  • The potential of Artificial Intelligence in image reconstruction

Who Should Attend?

Researchers (including undergraduates, graduates, postdoctoral fellows and principal investigators) and technologists in the medical imaging field and other biomedical sciences who are interested in gaining a better understanding of PET image reconstruction.


Dr. Charalampos Tsoumpas, Icahn School of Medicine at Mount Sinai, New York

Dr Charalampos (Harry) Tsoumpas is a Lecturer of Medical Imaging at the University of Leeds and Adjunct Professor at the Icahn School of Medicine at Mount Sinai, New York. He received his Ph.D. from Imperial College in 2008 and, then as researcher at Imperial College and King’s College.

Dr. Josep Oliver

Bruker senior NMI image reconstruction expert

Dr. Josep F Oliver is working at Bruker corp. in the R&D pre-clinical division as a senior NMI image reconstruction expert. Along the last years, his research has focused on the development and implementation of image reconstruction algorithms for imaging systems based on emission tomography; specifically, PET scanners and Compton cameras.


Input value is invalid.

Are you already in contact with your Bruker representative regarding any product inquiries?

We constantly want to improve our service for our customers. In answering the following question you help us to serve your needs even better in the future: What best describes your situation?

By ticking this box, I agree to receive, from time to time, emails from Bruker and its affiliates within the Bruker Group on upcoming events, webinars, our products and services, surveys and Bruker's corporate news.
I can unsubscribe at any time, by contacting Bruker or clicking on the opt-out link in the email if available. For more information on the processing of your personal data, please check Bruker’s Privacy Policy. 

By submitting this form I agree my personal data will be used to process my registration to the webinar. I have read and accepted the Bruker Website Privacy Notice ( and I agree to the Terms of Use ( of the Bruker website.

Already registered and lost your invitation link?

Thank you. The invitation link has been resent.