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NMR* International COVID-19 Research Network at Work - Part 2
Webinar Overview
In the current worldwide COVID-19 pandemic situation, fast developments are needed, not only in vaccines, but also in analytical techniques to detect the infection, predict outcomes during hospitalization, and more and more important towards Long COVID. Successful development of diagnostic routines needs a large number of samples and spectroscopic data generated thereof as well as comprehensive metadata coverage.
Initiated by Bruker and under the guidance of the Australian National Phenome Center (ANPC) run by Prof. Jeremy Nicholson, a worldwide international COVID Research Network consisting of several institutions collaborate, using completely standardized NMR procedures producing spectral data, exchangeable and enabling integration across the Network. In the webinar, prominent members of the Network will present the advantage of exchanging data and their results along with detection, outcome prediction, and Long-COVID risks and monitoring.
Nuclear Magnetic Resonance (NMR)* spectroscopy technology is a robust analysis technique that can provide a solution to the challenges of COVID-19 diagnosis and prediction based on metabolic changes caused by the virus once RUO results can be transferred into certified routines. The concept of phenoconversion and phenoreversion has been developed to follow these changes upon infection up to recovery. Applying NMR spectroscopy with its unique reproducibility and transferability enables the development of sensitive and specific routines for COVID analysis. This information is vital to develop diagnostic and predictive actions because NMR can connect metabolic information with systems biology on a personalized basis. Because of these advantages, NMR has the potential for the development of effective health monitoring, allowing early detection and treatment effects.
Additionally, the webinar speakers will discuss the level of complexity COVID-19 presents for emerging technology applications and scientific concepts. The mass scale of the pandemic encouraged international collaborative efforts to meet the challenges posed by the global outbreak of COVID-19. Initial research and development took old knowledge of treatments and techniques and attempted to adapt it in new ways to the current viral situation. This is where the need for powerful tools such as NMR presented itself most obviously.
Wednesday July 07, 2021
Time: 05:00PM Central European Summer Time
Key Topics
- How experimental data suggest that NMR* metabolic profiles are suitable for COVID-19 patient stratification and post-treatment monitoring
- How Standard Operating Procedures (SOP’s) guarantee the high spectral quality and reproducibility for the generation of identical spectra, independent of the lab, user, and system
- How strong collaboration among research groups worldwide is ensured because of the strict standardization of the Bruker Avance IVDr platform*
- How NMR* quantify hundreds of metabolites in a mixture in one single acquisition, without separation, turning biofluids into data.
Who Should Attend?
This webinar is of particular interested to heads of clinical research, heads of clinical chemistry, regulators and payors, University Hospitals and Medical Universities, Institute for Clinical and Experimental Medicine, Metabolic centers, Medical Doctors doing research in oncology, diabetes, infection, pediatrics, cardiology, epidemiologist.
* Bruker NMR Instruments are for research Use Only. Not for Use in Clinical Diagnostic Procedures.
Speaker
Ulrich Günther
University of Lübeck, Professor of Metabolomics - Institute for Chemistry and Metabolomics
Christoph Trautwein
Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital, Eberhard Karls University Tübingen, Group Leader Metabolomics & Systems Medicine
