Single Crystal X-ray Diffraction (SC-XRD)

SC-XRD Sources

X-ray sources are one of the key components of diffraction systems for structural biology and chemical crystallography. A successful diffraction experiment starts with an excellent X-ray source.

SC-XRD Sources

METALJET D2 PLUS

The METALJET D2 PLUS for X-ray diffraction delivers the smallest and most intensive X-ray beam of any home lab X-ray source to meet the ever increasing demands of modern structural biology including protein crystallography and Small Angle X-ray Scattering.

IμS DIAMOND II Source

The IµS DIAMOND II combines rotating anode performance with the comfort of an air-cooled sealed tube system. The IµS DIAMOND II is available for Copper (Cu), Molybdenum (Mo) and Silver (Ag) radiation.

IµS 3.0 Source

The IµS 3.0 is the first-ever microfocus source designed from the ground up for crystallography.

Sealed Tube

Our water-cooled sealed tube X-ray source delivers a large top-hat-shaped beam with excellent intensity for large and medium sized crystals in chemical crystallography.

METALJET D2 PLUS

METALJET D2 PLUS

The Most Powerful Liquid Metal Jet X-ray Source for Chemical and Biological Crystallography

The METALJET D2 PLUS for X-ray diffraction delivers the smallest and most intensive X-ray beam of any home lab X-ray source to meet the ever increasing demands of modern structural biology including protein crystallography and Small Angle X-ray Scattering (SAXS). Consequently, the METALJET D2 PLUS enables you to collect data on smaller, more weakly diffracting crystals.

The world’s strongest in-house X-ray source is now even more powerful: 250 W power load on the target, extended cathode lifetime with longer uptimes and further reduced maintenance requirements define the next generation, the new METALJET D2 PLUS.

In the METALJET D2 PLUS the solid target of conventional rotating anode generators is replaced by a high-speed jet of liquid metal that can accept a much higher power load. The result is an X-ray beam that is much brighter than traditional home sources.

METALJET D2 PLUS X-ray Source

HELIOS MX optics for METALJET D2 PLUS transmits the X-rays to the crystal

To deliver such a small X-ray beam required technical innovation in the design of the X-ray optic with greater precision in the d-spacing of the multilayers. The HELIOS MX optics for METALJET D2 PLUS transmits the X-rays to the crystal in a uniformly small diameter, greatly exceeding the intensity of conventional X-ray sources.

 

The METALJET D2 PLUS was developed in collaboration with Excillum and is fully integrated into the D8 VENTURE cabinet, resulting in a small-footprint diffraction system. The source mounts directly on the goniometer ensuring easy and stable downstream alignment guaranteeing an excellent overall system precision.

By default, the D8 VENTURE with METALJET D2 PLUS is shipped dual-port ready, with a second port ready for another diffraction experiment, e.g. for BioSAXS investigations.

The level of integration makes the difference between a MetalJet and the Bruker METALJET D2 PLUS.

  • Highest X-ray intensity due to exclusive patented liquid-metal-jet technology. One order of magnitude greater power load than conventional rotating anode X-ray sources.
  • Unprecedented brightness resulting from the extremely high power loading and smallest electron focus.
  • Perfect spot quality is achieved through the high-brightness LaB6 cathode and smooth, self-regenerating, liquid metal target which provides exceptional spatial and emission stability.
  • Lower noise as the shorter-wavelength gallium Kα X-rays (λ = 1.34 Å) result in reduced background scatter and higher detector efficiency.
  • Lower running costs are ensured by the low power consumption, minimal cooling requirements, and the self-regenerating target.
  • Newly introduced "Dynamic Adaptation Technology" delivers an even more stable X-ray beam with increased up-time and reduced service costs
     

IμS DIAMOND II

IμS DIAMOND II Microfocus X-ray Source

Twice the intensity, proven reliability

The new Incoatec IμS DIAMOND II once more pushes the limits in microfocus source technology for crystallography:

  • Twice the intensity for faster data collection from smaller crystals
  • Five-year typical tube lifetime with an average intensity outperforming rotating anodes.
  • Nearly instantaneous automated wavelength switching in dual wavelength configurations

The IμS DIAMOND II incorporates two major technical innovations:

  • Hybrid metal-diamond anodes with isotopically pure diamond. This permits a higher electron power density on the anode and hence a brighter X-ray source.
  • New high-brightness cathode technology producing a more homogenous, higher current density electron beam to fully exploit the potential of the new isotopically pure diamond hybrid technology.

The IμS DIAMOND II - a strong family heritage

Since its introduction in 2006 more than 1700 IμS sources have been installed and over 96% of these are still operational. This makes the IμS both the world’s most successful and the most reliable microfocus source. The enhanced performance of the fifth generation IμS DIAMOND II is coupled with all the operational advantages which have made previous IμS generations so successful:

  • Air-cooling for unrivalled long-term stability with minimized installation requirements.
  • Optimum anode take-off angle for crystallography for higher intensity at the sample and thus better data.
  • Long tube lifetime, typically five years.
  • No other routine maintenance required.

IμS 3.0

IμS 3.0 Microfocus Source

Designed from the Ground up for Crystallography

The IµS 3.0 is the first-ever microfocus source designed from the ground up for crystallo-
graphy. Conventional microfocus sources adapt technology that was originally developed for radiography (non-destructive testing) and are thus not optimal for X-ray diffraction.

The IµS 3.0 makes no such compromises: every aspect of the source is specifically designed and manufactured for X-ray crystallography.

This means that you get a much brighter beam than ever before: up to twice the intensity of conventional microfocus sources. The IµS 3.0, available in our D8 Solution Second Generation, also features significantly better stability than conventional sources.

Best of all, the IµS 3.0 retains the legendary reliability and long tube lifetimes of the IµS family, still backed by the industry leading 3 year warranty.

  • Up to twice the intensity of conventional X-ray microfocus sources
  • Completely air cooled
  • Very low power consumption
  • Very long tube lifetimes
  • Very little decay of intensity with time
  • Most stable X-ray output
  • Hermetically sealed, He-purged beampath
  • High reliability, 3 year warranty

Available in the D8 QUEST and D8 VENTURE with Cu, Mo and Ag Kα radiation.

Sealed Tube

Sealed Tube X-ray Source

Large top-hat-shaped beam with excellent intensity

Our water-cooled sealed tube X-ray source delivers a large top-hat-shaped beam with excellent intensity for large and medium sized crystals in chemical crystallography. The source can be combined with a flat graphite monochromator for Cu and Mo radiation. The TRIUMPH monochromator is available for Mo radiation as an alternative to further increase the intensity. The sealed tube is powered by 3 kW highly-stabilized medium-frequency generator featuring an automatic monitoring of all important parameters as part of the DAVINCI concept.

Since both, tube and generator are water-cooled heat dissipation to the air is minimized.

  • Automatic burn-in of X-ray tubes to facilitate maximum tube lifetime
  • Ramp-up and ramp-down to stand-by of the X-ray generator by software

For smallest crystals in chemical crystallography higher intensity sources, such as the IμS 3.0, IµS DIAMOND II or the METALJET D2 PLUS are available. These sources also should be used for the investigation of protein crystals.

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