Preclinical Imaging

ParaVision 360 PET/MR

The Most Advanced Software for Preclinical Imaging Research

True Multimodality

One software for PET and MRI

Modern imaging laboratories hosting PET/MR instruments profit from the fully integrated common imaging platform spanning PET and MRI modalities. The simplicity and uniformity across the range of instrumentation allows operators to put their focus on their research.

Consistent Workflow for PET and MRI

Users of PET/MR instruments profit from a commonality between workflows, image processing and analysis, and data structure and management, all of which make operation faster and easier. Common terminology between the modalities and integrated single and multimodal workflows provide optimal clarity during scanning.

Efficient Animal Imaging

Animals are quickly positioned within the MRI and PET using the touchscreen of the Animal Transport System (ATS). Its accuracy guarantees perfect positioning correspondence between the two modalities and enables multistation acquisition for largest Field Of Views.

MR-based Automatic Attenuation Correction Maps

PET attenuation correction maps are automatically calculated taking the animal, the animal cradle, and the RF coil into account. Stitched datasets, obtained with multistation acquisition are used for animal attenuation.

The attenuation correction platform is furthermore open for individual research on correction algortioms.

Full PET Functionality

Advanced PET Scanning

PET scanning is enhanced by such options as capture mode based on total time or total counts, definition of energy windows and limits, and animal cradle position shifting between frames. Additionally, dynamic reconstructions can be performed when the data is saved in List Mode format.

Seamless Analysis

Multimodal data is automatically coregistered and common image processing, viewing, and analysis tools, such as fusing, make evaluation straightforward and easy.

Restrospective Cardiac Gating

IntraGatePET improves quantification of cardiac data via retrospective gating using MR navigators.
*work in progress

Innovative New Features

  • Common terminology between instruments
  • Common integrated multimodal workflows
  • Common image processing, viewing, and analysis tools and functionalities
  • Common dataset structure and management
  • Automatic coregistration of PET and MRI data
  • Automatic MR based PET attenuation correction
  • Static and dynamic image acquisition
  • Retrospective cardiac and respiratory gating and reconstruction
  • Kinetic time course image reconstruction and segmentation
  • PET random-, scatter-, and dead-time correction
  • PET isotope decay correction
  • Automatic MR-based PET attenuation correction
  • Open Attenuation Correction Platform

Applications

MR-based PET attenuation correction maps are automatically calculated, taking the animal, the animal cradle, and the RF coil into account. Stitched datasets, obtained with multi-station acquisition are used for animal attenuation.

  

As opposed to rigid body registration, data-driven affine registration based on mutual information (MI) leads to correct fusion of multimodal data

   

Intrinsic synchronization of FDG PET and MRI cardiac data acquisition with IntraGatePET in mouse heart. Courtesy: W. Gsell, U. Himmelreich, C. Deroose, KU Leuven, Belgium

  

Support

Service and Life Cycle Support

Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory