Dissolution of tablets
The dissolution process of a tablet can be characterized using magnetic resonance techniques, which enables to acquire in-vivo images, localized quantitative and qualitative spectra, and track the molecular diffusion of pharmaceutical compounds.
A tablet is a drug delivery system which ensures that the pharmaceutical ingredients are available at the targeted location with the right concentration and timing. The dissolution process of a tablet can be characterized using magnetic resonance techniques, which enables to acquire in-vivo images, localized quantitative and qualitative spectra, and track the molecular diffusion of pharmaceutical compounds.
Orthogonal gradient Echo images (axial, sagittal, coronal) of a tablet. Tablet was Tablet submerged in silicon oil under vacuum for 2h prior to acquisition.