To reach the clinic in record time, it’s crucial to develop new therapies in systems that reflect human disease, which can be achieved by using animal models. In cancer research, many animal models are available and in the field of immuno-oncology research, these animal models are used to evaluate new immunotherapeutic agents like antibodies, cancer vaccines, immuno checkpoint inhibitors, adoptive cell transfer, etc. Preclinical imaging can be a valuable tool to evaluate biomarkers and their diagnostic value, their ability to identify (non-)responsders, their predictive value and even treatment response in a non-invasive and longitudinal manner.
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