Optimization of costly NMR spectrometer acquisition time while maintaining short turnaround times are of peculiar importance for analytical services, usually dealing with large number of samples. For structural analysis, a significant step was achieved with the use of Non-Uniform Sampling (NUS) for 2D acquisition on a routine basis. Now, with the introduction of a tool like SmartDriveNMR, further optimization in full automation is possible to find to find the optimal acquisition parameters for the desired spectral quality.
Selecting the appropriate NMR acquisition parameters to ensure adequate spectral quality while limiting the acquisition time has always been a challenge in NMR, requiring training and experience. Non-Uniform Sampling was a significant milestone to limit acquisition time, yet it also even complicated parameter selections. Without prior scouting analysis, even advanced user may fail, ending up with low quality data and/or wasting spectrometer time.
To try to tackle these challenges, Evotec ID Lyon has implemented SmartDriveNMR for its routine structural analysis workflows. This webinar will present this use case, towards automated, failsafe on-the-fly optimization of NMR acquisition for structural analysis.
OCTOBER 17, 2023 - 4PM CEST | 10AM EDT
This webinar will be of interest to people who own or work with AVANCE Neo but also AVANCE 3 for liquid state NMR with any kind of sample changer.
Dr. Valentin Poirier
Solutions Product Manager BioPharma, Bruker BioSpin
Valentin joined Bruker BioSpin in 2024 as a Solution Product Manager in the BioPharma team. In this role, he collaborates with the pharmaceutical industry to advance Nuclear Magnetic Resonance solutions tailored to drug development and manufacturing, with a strong emphasis on quality control and compliance. A trained chemist, he entered the pharmaceutical industry after completing his Ph.D. Over the past decade, he has managed analytical platforms at CROs (Albhades and Evotec), focusing on NMR and Mass Spectrometry as modern tools for analytical sciences and regulated applications (GMP/GLP). As a technical expert, he has contributed to the development of dozens of analytical projects for pharmaceutical applications and quality control, with a customer-centric and problem-solving approach.
Dr. Bjoern Heitmann
Product Manager for SmartDriveNMR at Bruker BioSpin
Studied physics at both undergraduate and PhD level, with his postgraduate studies focused around protein NMR. Since then, Bjoern has undertaken multiple postdoc positions before joining Bruker BioSpin in the R&D department. Bjoern has been with Bruker since 2006 and currently heads the Software R&D department.