Real-time PCR test
The Carbaplex® IVD-CE PCR Kit is a multiplex real-time PCR test for the five most prevalent carbapenemase gene families; providing rapid results with high sensitivity and specificity without the need for culture.
Carbapenemase-producing Enterobacteriaceae (CPE) are a global public health risk. The genes coding for carbapenemases are readily transmissible in healthcare environments and cause outbreaks. Combatting the spread of these genes requires rapid identification of carriers, robust infection control and prevention procedures. Bruker’s Carbaplex® IVD PCR Kit enables the rapid identification of CPE colonized patients; allowing the efficient use of healthcare resources and appropriate patient management.
CPEs are a serious healthcare problem. They are resistant to the carbapenem class of antibiotics, which are often considered the ‘last-line’ of therapy for treating multi-drug resistant gram-negative bacteria:
The Carbaplex® IVD PCR Kit is a multiplex real-time PCR assay for rapidly identifying patients carrying CPEs, detecting and differentiating the five most prevalent carbapenemase genes from a single sample:
For the confirmation of carbapenemase activity, the MBT STAR®-Carba assay is available, which runs on the MALDI Biotyper® IVD systems.
The Carbaplex® IVD PCR Kit provides results in under 3 hours, compared with days for culture-based screening approaches, helping the laboratory to rapidly inform the infection control team when time matters.
The Carbaplex® IVD PCR Kit is an easy-to-use master-mix format and is designed to be compatible with existing laboratory equipment, minimizing the need for dedicated bench space or additional training:
The Carbaplex® IVD PCR Kit is suitable for use in high-throughput testing scenarios using DNA extracted from rectal swabs, or for confirmation testing of suspected isolates.
Please contact your local representative for availability in your country.
Not for sale in the USA.
As of May 2021, Bruker Daltonik GmbH is now Bruker Daltonics GmbH & Co. KG.