AVANCE NEO-X Consoles

The AVANCE NEO-X redefines NMR performance with a compact, modular design and next-generation electronics. Its fully modular, independent RF channel architecture (TRX1200) enables true multi-channel operation and ultra-fast control, supporting advanced multi-receive experiments and flexible configurations.

With a high intermediate frequency and advanced GaAs preamplifier technology, NEO-X delivers enhanced sensitivity*, especially for X-nuclei in a broad frequency range. Integrated SpinPilot automation, second-generation ATMA, and fast 3rd generation Bruker digital lock ensure easy and fast setup of virtually all state-of-the-art NMR experiments. Also new with the AVANCE NEO and NEO-X architecture is the concept of an embedded acquisition server and an associated client-server software architecture (TopSpin 4 and 5). This leaves the spectrometer independent of the client computer, thus giving the user the opportunity to control the system via an operating system and location of choice, like the cloud.

Backward compatibility with existing probes, autosamplers, and magnets protects your investments, while optimized electronics reduce energy consumption and heat dissipation for sustainable, cost-effective operation.

Designed for advanced NMR methodologies and future upgrades, the AVANCE NEO-X is ready to meet the evolving needs of modern research labs.

*Compared to AVANCE III HD and earlier generations

Leveraging the proven performance of the AVANCE NEO architecture, NEO-X delivers a compact, modular solution tailored to the needs of researchers and NMR lab managers. Its design ensures seamless integration with existing infrastructure while offering advanced capabilities for cutting-edge research.

Scientific Excellence & Data Integrity
The AVANCE NEO-X console is built on a robust hardware platform featuring fully modular, independent RF channels based on the TRX1200 transceiver. Enhanced sensitivity and dynamic range enable reliable detection of even low-concentration samples and complex mixtures, ensuring the highest data quality and reproducibility for robust, publishable results.

Automation & Ease of Use
With automated workflows and intuitive operation, the AVANCE NEO-X streamlines both routine and advanced NMR experiments for users at all experience levels. Integrated SpinPilot automation and second-generation ATMA technology enable fast, reliable probe tuning and matching, reducing training time and administrative effort.

Scalability & Compatibility
The modular, upgradeable design of the AVANCE NEO-X allows you to expand system capabilities as your research evolves. Backward compatibility with existing magnets, probes, and autosamplers, plus a space-saving footprint, protects your investments and simplifies integration into any laboratory environment.

Future-Proof Innovation
Designed to support advanced NMR techniques - including broadband homonuclear decoupling, ultrafast 2D NMR, and multi-receive experiments - the flexible architecture ensures your laboratory remains at the forefront of NMR research for years to come.

Sustainability & Efficiency
Reduced energy consumption and heat dissipation lower both operating costs and environmental impact. Optimized electronics and proactive maintenance features, such as integrated autodiagnostics, help your institution meet sustainability goals while maintaining high performance and reliability.

Advanced Diagnostics & Control
Built-in network analyzer, digital oscilloscope, and comprehensive onboard diagnostics provide real-time insights and troubleshooting. Precision gradient amplifiers and NMR Thermometer™ temperature control ensure stable, high-quality results even during demanding experiments.

• RF Channels: Up to 8 fully modular, independent RF channels; architecture based on TRX1200 transceiver
• Intermediate Frequency (IF): >1.8 GHz for clean detection and minimized noise folding
• Sensitivity: 6–8% increase for low γ nuclei (compared to AVANCE III and previous generations)
• Frequency Range: 15–600 MHz broadband RF amplifiers
• Automation: Integrated SpinPilot automation with TopSpin 5 software
• Tuning & Matching: 2^nd generation Automatic Tuning & Matching (ATMA) with factory-calibrated preamplifiers
• Diagnostics: Built-in network analyzer, digital gradient channel oscilloscope, and onboard diagnostics
• Temperature Control: NMR Thermometer™ using ²H spins for stable sample temperature
• Compatibility: Backward compatible with legacy probes, SampleJet, SampleCase, and all existing superconducting magnets
• Footprint: Compact, modular design (Onebay, Twobay, Nanobay configurations)
• Power Efficiency: Reduced energy consumption and heat dissipation
• Maintenance: Integrated autodiagnose functionality for proactive service
• Software: TopSpin 5 with advanced automation and diagnostics