MALDI Mass Spectrometry

Build a core lab with user-friendly systems for every researcher

Advanced capabilities that elevate your core lab‘s research

Walk-Up System
Accessible for new or experienced users with wizard-driven workflows and automated setup. Transform complex analytical challenges into routine measurements.
MALDI Imaging
Explore MALDI Imaging with automated setup in under 20 minutes. Contextualizing molecular expression with spatial biology toolkit for breakthrough research.
Direct Analysis
Analyze insoluble species without complex sample preparation. Access protein complexes, aggregation-prone proteins, and hydrophobic materials up to 500 kDa.

Deliver scalable research to be a hub of innovation and discovery

Synthetic Biology/Genomics

  • Bio-orthogonal chemistry
  • Click chemistry libraries of biological probes
  • DNA damage repair molecular tools
  • DNA-PNA libraries
  • RNA pull down screening
  • Affinity pull down assays
  • Host-binding or cross-linking monitoring

Pharmacology

  • Intact proteins
  • Antibody-drug conjugates
  • Lipid nanoparticles
  • Top-down protein sequencing
  • Screening different modalities
  • Spatial distribution of drug targets and metabolites
  • Spatial localization of natural products
  • Spatial analysis of drug toxicity

Beyond Biology

  • Organic synthesis characterization
  • Chemical probe libraries
  • Sensor and catalyst materials
  • Nanoscale structures
  • Molecular topology and self-assembly
  • Polymeric materials molecular weight/end-group/side-chain determination

Expanded Biology

  • Host-pathogen interactions
  • Biofilms
  • Developmental biology
  • Plant biology
  • Glycobiology
  • Spatial analysis of tissue and single cells

Comprehensive Molecular Characterization Beyond Simple Identification

Unlock complete molecular stories with advanced MALDI applications. Access the missing 30% of membrane proteins that remain invisible to conventional analysis methods.

These critical hydrophobic species represent essential drug targets, biomarkers, and functional regulators crucial for understanding protein networks and metabolic pathways. 

Expand protein characterization workflows to reveal functionally distinct proteoforms that drive biological processes. Enable precise confirmation of click chemistry products, PNA-protein conjugate validation, and antibody-drug conjugate integrity verification. Map post-translational modification combinations on single molecules with unparalleled precision.

Decode the hidden language of glycosylation with comprehensive glycan analysis. Over 50% of human proteins carry glycosylation modifications that regulate protein folding, trafficking, and function.

These cellular communication molecules serve as biomarkers, determine drug efficacy and toxicity, and mediate cellular signaling pathways essential for biological understanding. 

Transform spatial molecular information into actionable insights. Biological processes occur in specific locations within tissues and cells.

Spatial analysis contextualizes disease development, drug penetration, and cellular communication networks, providing the molecular geography essential for translational research success.

Streamlined Workflows from Sample to Results in Record Time

Eliminate complex sample preparation that sacrifices data quality. MALDI provides robust, well-established workflows for challenging samples including protein complexes, cross-linked assemblies, and hydrophobic synthetic materials.

Direct analysis capabilities handle masses up to 500 kDa without compromise. 

Stay ahead of technological advances by generating AI-ready datasets optimized for machine learning analysis and pattern recognition. Maximize the utility of your library and screening data through standardized, high-quality molecular information that integrates seamlessly with modern analytical workflows.

Transform complex analytical challenges into routine measurements with effortless monitoring capabilities. Fast data acquisition across large sample volumes makes tracking mass shifts for cross-linking and host-guest chemistry straightforward. Automated workflows scale from single samples to high-throughput studies. 

Validate synthetic biology and polymer products with confidence through molecular-level characterization.

MALDI's soft-ionization capability enables precise assessment of polydispersity, end-group analysis, and bioconjugate polymer characterization for drug delivery applications, ensuring materials chemistry success.

neofleX presents an incredibly versatile opportunity in ease-of-use for entry-level researchers wanting to expand their biomedical applications.

Carsten Hopf, Ph.D., Professor, Head of CeMOS - Center for Mass Spectrometry and Optical Spectroscopy, M2Aind Industry Consortium, Mannheim, Germany

A complete ecosystem for full ease-of-use

  • Enjoy entry level accessibility with research-grade results
  • Standard workflows that get you going from consumables to software
  • Future-ready and scalable platform for expanding research needs
  • Expert support for continued success

 

For Research Use Only. Not for use in clinical diagnostic procedures.