NMR Automation

SampleJet

Enable unattended, high throughput, reproducible NMR workflows from sample preparation to data acquisition - maximizing instrument utilization while reducing manual effort, errors, and time to result.
SampleJet transforms NMR from a manually fed instrument into a scalable, autonomous analytical platform -maximizing throughput, consistency, and confidence while minimizing human dependency.

Transform NMR into an Autonomous Analytics Platform

Faster Turnaround.
Higher Utilization
Efficient handling of daily routines
More Than
Automated
Sample Transfer
Seamlessly integrating NMR into modern day lab environments
Traditional Workflows Were Not Designed for Today's Workloads
Including 96 well plates and individual tubes
Get the Best Results from your SampleJet with Bruker Consumables
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Full Automation. Minimal Footprint.

With SampleJet, NMR completely blends into the scenery of modern lab automation. SampleJet requires no additional laboratory space beyond the NMR magnet footprint and can be mounted on magnets from 300 to 1200 GHz. Continuous NMR sample tube automation is enabled in the standard microtiter-plate format, enabling automated preparation of liquid-state NMR samples in industry standard automated pipetting systems and continuous unattended processing in the spectrometer.

Features

  • Spinner-free open access applications: eliminate the need for spinners. SampleJet assemble the tube with shuttle, garanteeing insertion depth in the probe within 0.2mm for repeatable shims
  • 96 positions for standard 7” NMR tubes; 3 positions for standard samples with spinners
  • Setup pre-defined carousel positions and simplify routine calibrations with Bruker NMR reference standards or your own
  • Five positions for well-plate sized NMR tube racks for batches of up to 480 NMR sample tubes.
  • Automated switching between 5mm, 3mm, 1.7 or 1.0mm sample tube diameters to support higher sample concentration and improved sensitivity .
  • Automatic tube and rack bar code identification
  • Highest-speed sample exchange times for optimized high-throughput NMR workflows
  • Ability to insert urgent samples
  • Repeat measurements without unloading the entire batch
  • Interrupt a batch queue with the addition of a priority sample
  • Removal of samples or racks while the system is running
  • Active capacity management for efficient removal of completed sample analyses
  • Native integration to TopSpin™ and SpinPilot ™ spectrometer software
  • Compatible with modern AvanceNeo consoles, as well as legacy AVANCE generations

Applications

Industrial automation applications

  • Compound management QA
  • Batch screening applications
  • Routine NMR
  • Synthesis control
  • Special applications

 

Typical laboratory requirements

  • Centralize valuable analytical assets
  • Standardize workflows and increase experimental throughput
  • Optimize sample turn-around-time from receipt of customer sample to communication of results
  • Standardize on sample identification and registration workflows
  • Standardize sample preparation routines (and sample container formats)
  • Improve workflow standardization, while preserving workflow flexibility driven by dynamic sample prioritization

Specifications

High-Throughput Tubes and Caps

Bruker offers:

  • Unracked as well as single (1 x 96 tubes) and multiple rack (5 x 96 tubes) products
  • As standard, each of the products includes patented shape caps with narrow angular tolerances, ECC200 coded to allow:
    • Tracking of samples and experiments with a 10-digit unique code, written both in machine-readable form and in human-readable numbers
    • The first 2 digits identify the tube diameters, the next 8 digits are a unique serial number
    • IDs mitigate errors due to incorrectly labeled samples, damaged barcodes, tube placement errors and missing samples
  • Chemical resistance to common portfolio of NMR solvents such as CdCl3, MeOD, and DMSO
  • Operation validated for use between from 4 °C to 60 °C
  • Open or closed caps:
    • Open are ideal for applications requiring rapid access, easy pipetting, or frequent sample manipulation
    • Closed caps help minimize evaporation, reduce contamination risk, and support safer handling during storage or automated processing.
  • Open and closed cap types are fully compatible with POM balls, ensuring:
    • Tight sealing
    • Simple visual cues to differentiate samples based on lab or user or solvent type

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More Information

Sample Jet Walk-Up Workflow