DISCOVER small molecule-induced conformational changes: an assay to detect protein conformational changes using DNA origami nanolevers
Webinar Overview
In this episode of the Bruker Biosensors DISCOVER MOLECULAR INTERACTIONS webinar series you will learn how to detect binding-induced conformational changes of proteins using electrically oscillated DNA origami nanolevers and fluorescence.
Key Learning Objectives
This webinar is part of the webinar series DISCOVER MOLECULAR INTERACTIONS by Bruker Biosensors. Pablo Porragas Paseiro will show the newest advances and data on conformational change analysis with switchSENSE®.
In this webinar, you will learn how tethering a target protein to an electrically oscillated DNA origami nanolever can give you insights into the effects of small molecule analytes on the conformation of the protein. A dataset of different proteins will be presented and Pablo will shed light on the dynamic surface energy transfer measurements behind the results.
Frequently asked questions about this biosensor assay will also be discussed. This webinar will be helpful for anyone in search of a method that enables the detection of binding-induced conformational changes.
Speaker
Pablo Porragas Paseiro
Early Stage Researcher, Bruker Biosensors, Munich, Germany
Recording
*仅供研究使用，不能用于临床诊断程序。