dsm-firmenich Science & Research

At dsm-firmenich, we’re at the forefront of innovation in nutrition, health, and beauty. We create sustainable solutions that impact our daily lives. Our cutting-edge approaches drive progress, with one area of focus being the development of novel bioprocesses.

In our R&D lab, we regularly use Nuclear Magnetic Resonance (NMR) to screen new fermentation processes. These advanced bioprocesses involve complex mixtures of media components and metabolites. Our goal is to gain an in-depth understanding and enable data-based development of new procedures.

Through our long-standing partnership with Bruker, we have been testing the latest software release from their Advanced Chemical Profiling Solution. This supports the development of the kinds of analytical workflows we use, seamlessly integrating data acquisition, processing, interpretation, and report filing. It streamlines analytical workflows and makes it easier to compare results.

Bruker’s software platforms can be used to support scale-up from development to manufacturing. As new production routes are rolled out into manufacturing, process monitoring with a benchtop NMR system would be feasible. Bruker’s Fourier 80 benchtop system, equipped with the same Advanced Chemical Profiling Solution, could support process control in production labs.

An integrated NMR methodology - combining high-field NMR in R&D labs with benchtop systems in manufacturing - opens exciting opportunities for the industry. End-to-end use of Bruker’s solutions can make it easier to develop efficient, scalable processes.