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布鲁克核磁共振方案系列网络课堂

核磁共振分析的线上资源

了解新知的绝佳机会。

欢迎来到布鲁克的线上虚拟会议室。在这个社交疏远和在家工作的艰难时期,布鲁克与大家一起,在这里为您提供服务,并将最新的技术和应用以线上活动的方式提供给您。本网站将包括所有数字通信的资源,包括教程、网络研讨会和产品视频。您还可以提交问题或要求与某位专家进行对话,就您的实验或问题做详细的讨论。

祝每个人都保持安全和健康!

4月线上软件培训课程

4月14日 - Quantitative NMR

Become familiar with a wide range of analysis types available in Mnova qNMR for qNMR concentration and purity/potency determinations. This will include manual, assisted or fully automated batch processing analysis.

 

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4月14日 - Quantitative NMR

Become familiar with a wide range of analysis types available in Mnova qNMR for qNMR concentration and purity/potency determinations. This will include manual, assisted or fully automated batch processing analysis.

 

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4月14日 - Quantitative NMR

Become familiar with a wide range of analysis types available in Mnova qNMR for qNMR concentration and purity/potency determinations. This will include manual, assisted or fully automated batch processing analysis.

 

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4月线上软件培训课程

4月14日 - Quantitative NMR

Mnova plugin qnmr

Become familiar with a wide range of analysis types available in Mnova qNMR for qNMR concentration and purity/potency determinations. This will include manual, assisted or fully automated batch processing analysis.

 

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4月15日– Chemical shift perturbation analysis by NMR

Product logo binding

Our colleagues Dr. Pablo Monje and (CEO) Santi Domínguez will demonstrate Mnova Binding, a chemical shift perturbation analysis tool for fragment-based drug discovery. Learn how to automatically process 2D HSQC type of protein-ligand titration spectra, track the peak movement and compute the Kd‘s for multiple peaks.

 

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4月17日 – Electronic Laboratory Notebook

Mbook

Our colleague will demonstrate Mbook, a professional web-based Electronic Laboratory Notebook designed, developed and, tested by scientists with very well defined user roles for research and manufacturing groups as well as analytical capabilities.

 

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近期布鲁克产品发布信息

FOURIER™ CrimeLab – Benchtop FT-NMR for Forensic Laboratories

Bruker Fourier CrimeLab

Bruker envisions that interconnected high-field NMR spectrometers at central forensic laboratories and benchtop FOURIER CrimeLab 80 MHz FT-NMRs at local labs will enable law enforcement to unambiguously identify suspicious known or new psychoactive substances. Benchtop FT-NMR is made easy for novices by the new push-button, non-expert software GoScan. Please watch our recorded webinar

Solve 3D structural challenges with Mnova StereoFitter

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StereoFitter is an advanced tool for 3D conformational and configurational analysis using experimental constraints from NMR spectra. Designed for chemists and researchers from different fields with questions about stereochemistry, StereoFitter contains all the tools needed to derive relative configuration and conformation in solution for small molecules by N

核磁实验室进阶: ENC 2020 产品发布

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在2020年3月美国ENC会议上, 布鲁克介绍了最新的核磁共振硬件、软件和服务。我们将在此网络课堂中向您一一介绍,其中包括1.2GHz的波谱仪和其他新产品,这些技术将有助于提升效率和核磁共振实验灵敏度。

 

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网络课堂

4月1日: NMR在Gxp环境中的应用

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NMR是一种全世界所有制药公司都采用的成熟的分析方法。目前随着市场的要求和监管力度的提高,越来越多的NMR仪器被要求在GLP和GMP环境中使用, 其应用范围涵盖了从原材料检验到产品上市整个过程。而遵守数据完整性(DI)原则和仪器资格认证是对这种仪器的强制性要求。为了响应客户的要求,Bruker提供了一个“GxP Readiness Kit”产品。它包括一套完整的资质协议以及支持IQ/OQ和计算机系统验证(CSV)的相关文档。此外,还提供了支持PQ的软件。本课程主要介绍了NMR如何在GXP环境中遵守数据完整性并完成3Q认证。

 

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4月7日 - EPR 技术更新和Magnettech ESR5000介绍

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The Bruker Magnettech ESR5000 is designed for today’s laboratory requirements. It combines easy operation with X-band research grade sensitivity and affordability. The magnet provides a wide field range without cooling water requirement. The robustness of the instrument allows it to be used in the laboratory and factory floor.

 

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4月2日 - INADEQUATE实验的原理、设置与应用

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INADEQUATE实验可以提供有机小分子碳骨架的连接信息。但由于实验灵敏度较低,使科研人员望而却步。然而现代高场核磁谱仪和超低温探头的出现已经减轻了这个问题。对于典型小分子,用10mg左右的样品量就可以得到有效的INADEQUATE谱图。这次报告将对INADEQUATE实验的原理,设置和应用等方面进行介绍,帮助用户提高对该实验的理解与运用。

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April 14 - Latest technology CPMAS CryoProbe

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Enabling advanced characterization of materials, natural products, biomolecules and polymorphs with a three-fold boost in sensitivity, the new CPMAS CryoProbeTM reduces the measurement time by one order of magnitude! Enhanced sensitivity through the use of cryogenically cooled electronics and RF circuitry, as well as optimized RF coil design, enable traditional solid-state NMR techniques on challenging samples.

 

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4月3日 - EPR-ROS与健康,浅谈EPR在生物医学方面的应用

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ROS一类活性氧类自由基,与健康有着密切的关系。本次直播将向大家介绍如何使用ROS,以及如何运用EPR的方法对其结果进行检测。

 

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4月 21 日- 核磁软件的深入学习

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During this webinar, Dr. Federico Paruzzo discusses the first NMR application based on artificial intelligence developed by Bruker: the automatic signal region detection for 1H NMR spectra. After presenting the team behind this effort, he gives some technical details on set up we used to develop this deep learning application and compare its performance with other TopSpin methods to detect signal regions. Finally, he demonstrates how to use this application in practice, and highlight some results obtained on experimental spectra. 

 

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4月 21日 - COVID-19的治疗:老药新用

COVID-19 is a global pandemic caused by the SARS-CoV-2 virus. There is a huge worldwide effort underway to discover vaccines and new drugs, and to repurpose old drugs to treat this disease. This talk will discuss the drugs that are currently being used to treat COVID-19: remdesivir, chloroquine and the combination of lopinavir/ritonavir.

Speaker: Niamh O’Boyle, Trinity College, Dublin

 

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4月 21日 - COVID-19的治疗:老药新用

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COVID-19 is a global pandemic caused by the SARS-CoV-2 virus. There is a huge worldwide effort underway to discover vaccines and new drugs, and to repurpose old drugs to treat this disease. This talk will discuss the drugs that are currently being used to treat COVID-19: remdesivir, chloroquine and the combination of lopinavir/ritonavir.

Speaker: Niamh O’Boyle, Trinity College, Dublin

 

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4月 29日- Rapid Narcotics Analysis by Orthogonal Methods: MRS meets NM

Webinar 29 april 2020 teaser

Detection of illegal drugs is an ongoing battle and the rapid analysis and identification of prohibited substances is critical to prevent their importation and widespread distribution.

 

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4月 22日 - 确保 PET的定量准确性

Webinar 22 april 2020 teaser

Positron emission tomography (PET) is not only a highly sensitive in vivo imaging technique, with a broad library of tracers, but it is inherently quantitative. This is the basis of the widely known metric SUV (Standard Uptake Value). However, producing accurate quantitative data requires the manufacturer to supply adequate tools and quality control protocols ideally in a user-friendly workflow.

 

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4月 21日 - COVID-19的治疗:老药新用

COVID-19 is a global pandemic caused by the SARS-CoV-2 virus. There is a huge worldwide effort underway to discover vaccines and new drugs, and to repurpose old drugs to treat this disease. This talk will discuss the drugs that are currently being used to treat COVID-19: remdesivir, chloroquine and the combination of lopinavir/ritonavir.

Speaker: Niamh O’Boyle, Trinity College, Dublin

 

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4月28日 - 基于多糖的疫苗的核磁共振特征

Banner outbreak 21 april final

Polysaccharide-protein conjugate vaccines are among the safest and most successful vaccines developed during the last 30 years. Since the first semisynthetic chemical conjugate vaccine licensed in the 1980’s to protect human against Haemophilus influenzae type b infection, conjugate vaccines against Neisseria meningitidis and Streptococcus pneumoniae have been developed and registered using the same approach (i.e. bacterial growth to produce capsular polysaccharide antigen and chemical coupling to carrier protein).

Speaker: Francesco Berti, 葛兰素史克,意大利锡耶纳

 

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Managing and delegating work remotely can be challenging for both small startups, and large biotechs. How can research teams manage workflow in a controlled, efficient manner? How can management limit the chance of repetition when working with multiple teams across the globe?

Image reconstruction is a fundamental part of PET allowing to generate 3D tomographic images of the tracer’s spatial distribution based on the position and timing of the detected annihilation gammas. PET reconstruction, common to other imaging modalities like CT and SPECT, apply algorithms whose mathematical details the general users may not need to understand. Nevertheless, a good knowledge on the performance characteristics of different algorithms can be highly beneficial to obtain reliable quantitative images more efficiently.

The ability to quantitate lung disease and monitor disease development and resolution in real time is an advantage to using small animal microCT. In addition, 3D analysis provides data about the whole lung instead of the snap-shots typically associated with conventional analysis techniques, including histology. microCT provides the ability to assess a large diversity of lung diseases and the outcomes correlated to data generated from human patients.

In this webinar, Dr Kalina Ranguelova from Bruker BioSpin, will provide an overview of various industrial and academic applications and literature examples using electron paramagnetic resonance (EPR) spectroscopy to understand paramagnetic behavior of different polymer materials.

COVID-19前线的布鲁克用户和技术

ANPC - 布鲁克用户在一线应对COVID-19

使用Avance IVDr更好地了解和缓解COVID-19病毒大流行的威胁。

先进的核磁筛选 IVDr 解决方案助力 COVID-19 研究

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西澳大利亚州的研究人员正在领导一场科研攻关,以了解为什么有的年轻健康的患者病情严重,甚至死于Covid-19,而有的年轻人却几乎没有受到影响。位于珀斯南部的澳大利亚国家表型组学中心(ANPC)是研究中心之一,该中心正在加紧研究,以找出这种现象发生的原因。

Launch of CE-IVD Marked genesig® Assay Kit for the Detection of the SARS-CoV-2 Virus

COVID 19 Bruker

COVID-19前线的布鲁克用户和技术

NMR 软件

NMR Software

TopSpin 及其他软件平台

磁共振

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布鲁克磁共振博客

NMR 网络研讨会

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现场直播与点播