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scimaX MRMS - 把科学推向极限

scimaX 让鉴定更可靠

常规的亚ppm质量精度和同位素精细结构(IFS)能力可以对已知和未知成分的份子式准确无误的测定。

以磁共振质谱MRMS为核心技术的scimaX

• 提供超高分辨率和质量精度;
• 让宽质量范围的IFS 分析成为日常操作;
• 给出高确信度的化合物鉴定。

 

 

 

 

Broadband IFSpng

scimaX方便的安装和维护

scimaX 为一体化磁共振质谱设计,具有7T场强的超导冷却磁体技术,其紧凑的尺寸可在标准实验室安装,较传统磁体不同的是无需再定期补充液氮液氦致冷剂和安装氦气排空管。

scimaX一体化和多用途

ESI 和 MALDI源是标准配置, 还可连接APPI, APCI, GC-APCI等离子源,
并有多种离子碎片模式 CID, (n)ETD, (n)ECD, MALDI-ISD。

Tabelle scimaX

scimaX 针对高难度复杂分析

诸如MALDI成像、代谢组学、石油组学等复杂体系,能在白天上班时间开展 ESI 试验,在下班时间采集 MALDI 成像数据,新一代scimaX磁共振质谱仪可让你实现全天候运行,从而极大地提高生产率。scimaX 可以承担需要非凡的科学洞察力和突破性的项目。

Learn more about Technical Details

scimaX - the latest MRMS technology for improved productivity

Continuing Bruker’s tradition to forge productivity from technological innovation, scimaX includes several innovative core technologies, to give you performance rivaling high field MRMS at your fingertips.

scimaX ion optics
scimaX ion optics

Patented ParaCell 2xR detector

scimaX comes standard with ParaCell 2xR and AMP detection technology.
The Paracell is a departure from traditional MRMS cell strategies and provides uncommon broadband ion stability resulting in resolution orders of magnitude above other detection schemes. The ParaCell in combination with Absorption Mode Processing algorithms is the prerequisite for routine access to Isotopic Fine Structure (IFS) Information.
Brukers 2xR MRMS instruments use magnetron control technology and the latest high sensitivity, low noise MRMS preamplifier, realizing scientists' long standing vision to exploit harmonics detection schemes and thus increase the experimental speed and instrument productivity without sacrificing resolving power.

7T conduction cooled magnet technology

Bruker‘s revolutionary 7T superconducting magnet technology is the basis of the smaller footprint scimaX MRMS system. This key innovation uses 'conduction cooling' technology, which removes the requirements to fill liquid cryogens or provide quench ducts.

The scimaX can be operated in a standard laboratory space, enabling a wider range of scientific disciplines to gain access to the power of MRMS technology.

Unique ESI/MALDI dual source

Only Bruker MRMS instruments allow operation of a unique ESI/MALDI dual source. This source is included with any scimaX and can either run liquid samples introduced via the Electrospray ionization (ESI) source or from MALDI samples. This highly sensitive MALDI source uses  Bruker's SmartBeam-II™ laser technology and provides several small focus diameters for various applications with different sample preparation techniques. Fast switchover between MALDI and ESI operation is controlled by a software pushbutton, so even simultaneous ESI/MALDI operation is possible.

dual source scimaX
scimaX includes Bruker‘s ESI/MALDI dual source.

Ion activation techniques

scimaX includes a variety of ion activation techniques, including ECD, ETD, CID, EDD, SORI-CID, MALDI-ISD, and NETD capabilities.

Learn more about Applications

scimaX brings “high hanging fruit” within reach …

… for applications like MALDI Imaging, Metabolomics, Petroleomics, and more

MALDI and MALDI imaging

Maldi imaging

scimaX is the ultimate MALDI imaging system for analyzing small to medium sized molecules. Its unrivaled eXtreme Resolution capability and sub- ppm mass accuracy, over a wide mass range, can differentiate images that are only mDa apart and are prerequisite for IFS analysis and formula confirmation.

Analyze complex mixtures directly with the speed and robustness of MALDI.  Visualize and map molecular distributions without molecular labels using MALDI imaging, and determine molecular changes occurring in spatially significant regions of samples.

MALDI Imaging

Phenotyping workflow for large cohorts

AXelerate 100

scimaX eXtreme Resolution allows for chromatography-free acquisition complementary to established NMR based solutions. The MRMS aXelerate workflow breaks free of LC throughput limitations and allows analysis of over 200 samples a day. This solution with MetaboScape based processing enables automatic annotation of molecular formulae for hundreds of known metabolites and molecular formulae generation for thousands of unknown analytes in complex samples for metabolomics and phenomics studies.

Phenotyping

Molecular Classification of Petroleum

Petroelomics

When seeing every molecule matters, MRMS is mandatory to unravel the potentially hundreds of isobaric species in complex mixture analysis, placing MRMS as the industrial standard for Petroleomics.  Now, scimaX enables high field performance at 7T, breaking conventional norms for complex mixture analysis.

Petroleomics

For Research Use Only. Not for Use in Clinical Diagnostic Procedures.