Peptides & Oligonucleotides:
Expert eBook for Pharma

Get a clear, practitioner‑focused overview of peptides and oligonucleotides across discovery, development, and quality control. This 36‑page free eBook brings together expert articles, tutorials, and case studies, covering therapeutic trends, analytical strategies, and regulatory expectations, with a special emphasis on NMR‑based characterization for TIDES. Ideal for scientists and teams seeking robust, transferable approaches to characterization and analysis. 

• Why rigorous structural analysis matters for TIDES and how high‑field NMR supports identity, stereochemistry, and higher‑order structure assessments aligned with regulatory expectations.
• Hands‑on NMR guidance for oligonucleotides, including example datasets across nuclei (¹H, ¹³C, ³¹P, ¹⁹F) and discussion of diastereomer quantitation and PS:PO ratios.
• A peptide case study (exenatide), illustrating primary and higher‑order structure readouts, probe choices, and time/sensitivity tradeoffs for efficient datasets.
• Therapeutic landscape snapshots, from peptide therapy applications to GLP‑1 manufacturing challenges and emerging process trends.
• Selected research highlights, such as targeted delivery concepts for RNA and DNA‑based modalities and examples of bioactive peptides with translational potential. 

• Discovery and medicinal chemists evaluating peptide or oligonucleotide candidates
• Analytical, CMC, and QC scientists building robust characterization workflows
• Process development teams integrating multi‑attribute methods into development and release testing
• Academic and industry researchers exploring translational TIDES applications