Bruker at MANA 2026: Advancing Metabolomics with Complementary Technologies
Bruker at MANA 2026
Meet Bruker at the Metabolomics Association of North America (MANA) Annual Conference, taking place at the University of California, Davis, September 8 - 11, 2026, and discover how next-generation metabolomics technologies are enabling deeper biological insights.
Explore the latest innovations across our metabolomics portfolio, including timsMetabo™, advanced trapped ion mobility mass spectrometry workflows, and complementary analytical approaches combining mass spectrometry and NMR.
Join us throughout the week:
- Bruker Lunch Seminar: “State of Metabolomics Services 2026: A Multimodal Metabolomics Showcase”
Join us on Thursday, September 10 at 12:00 pm to learn how combining trapped ion mobility mass spectrometry and high-resolution NMR delivers more comprehensive metabolomics insights than either technology alone. - Interactive Workshop: “Do and When Do We Need Single-Cell MSI? A Practical Decision Framework for Spatial Metabolomics”
Participate in an engaging forum exploring the promises, challenges, and practical considerations of implementing single-cell mass spectrometry imaging technologies. - Poster Oral Session: Stop by our poster presentations to discover new research insights, and connect with experts. Explore a poster highlighting how streamlined LC-HRMS workflows can improve efficiency and comprehensive screening in routine and post-mortem toxicological analysis.
State of Metabolomics Services 2026: A Multimodal Metabolomics Showcase Overview
The combination of metabolomics technologies expands our view of the metabolome. Using the shared cohort of pooled human plasma, pooled human urine, and homogenized food samples from the UC Davis dietary meal-challenge study, we apply two orthogonal technologies to the same standardized sample set to show what becomes possible when trapped ion mobility mass spectrometry and high-resolution NMR are treated as complementary rather than competing.
12:00 - 12:15 | A Flexible Ion Mobility Mass Spectrometry Framework for Metabolomics
Erica Forsberg, Ph.D., Vice President Metabolomics, Bruker
Mass spectrometry continues to expand the reach of metabolomics through 4D-Metabolomics™, integrating retention time, accurate mass, ion mobility, and intensity for deeper biological insight. The timsMetabo™ simultaneously acquires data for untargeted discovery and targeted quantification, delivering sensitivity comparable to triple quadrupole instruments. As a complement to NMR, trapped ion mobility mass spectrometry delivers cleaner, higher-confidence metabolomics data by increasing molecular coverage and sensitivity while reducing false positives through rapid, information-rich MS/MS acquisition on the same standardized plasma, urine, and food samples. We will highlight emerging approaches that integrate discovery- and quantitation-focused analyses, including exploration of hybrid workflows using the biocrates kit technology to support qualitative and quantitative metabolomics within a single analytical framework.
12:15 - 12:30 | Nuclear Magnetic Resonance Spectroscopy Delivers Complementary Insights Beyond MS
Kyle Rodriguez, Ph.D., NMR Applications Scientist, Bruker
Through the use of the Bruker Avance IVDr platform, NMR continues to expand the scope of metabolomics by delivering highly reproducible, non-destructive quantification of abundant metabolites and lipoprotein subclasses directly from native biofluids, while also enabling untargeted, statistically relevant studies. As a complement to mass spectrometry, NMR brings rugged, single point calibration quantification and structural corroboration to the same standardized plasma, urine, and food samples, uniquely filling gaps left by MS-based approaches. We will preview how this workflow performs alongside MS on shared material, made practical through the use of 1.7 mm i.d. NMR tubes, which allow a complete NMR assay to run on a small fraction of the sample volume traditionally required. Additionally, we will highlight how our fit-for-purpose and user-defined solutions expand the scope of what is quantifiable in these biofluid matrices.
12:30 - 12:45 | Discussion on NMR and MS Data Integration
Join us for an interactive discussion on the value of integrating complementary analytical technologies. Discover how combining NMR and MS datasets can unlock deeper biological insights and create new opportunities for metabolomics research.
Event Details:
- Date: Thursday, September 10, 2026
- Time: 12:00 - 12:45 pm
- Location: Ballroom A
- Venue: University of California, 1 Shields Ave, Davis, CA, USA
Do and When Do We Need Single-Cell MSI? A Practical Decision Framework for Spatial Metabolomics
As spatial metabolomics and lipidomics technologies evolve, mass spectrometry imaging (MSI) has become an indispensable tool for understanding molecular heterogeneity across tissues. One particular interest area among various MSI approaches is imaging of greatly reduced physical dimension at single-cell levels. While single-cell imaging presents obvious advantage in understanding cell specific metabolomics and lipidomics, challenges are also seen in many aspects not limited to technical developments.
This discussion forum will present the current frontiers of single-cell MS imaging technologies with demonstrations of its abilities in contributions to better molecular understanding of system biology at single-cell levels, and, at the same time, discuss practical and logistical considerations that each laboratory and institution will encounter when implementations of single-cell MSI are planned. It will empower participants to make informed decisions when considering new studies in this direction.
- Pre-polling from the Community: We will encourage any attendee to submit a single slide with image and figure legend, biological sample that benefits from single-cell resolution, OR even saying not needed.
- Live Polling via Slido or Zoom: Attendees will be polled at the start and mid-session to assess their experience levels and gather real-time feedback.
- Q&A and Chat-Based Interaction: A dedicated Q&A segment will follow each presentation block. Moderators will monitor chat throughout to answer quick queries live.
- Post-Session Networking: A follow-up online discussion board or Slack channel will be available for continued engagement.
Organizers:
- Leo L. Cheng, Ph.D., Associate Professor, Department of Radiation Oncology, Corewell Health Research Institute, MI, USA
- Prasanna Ashok Kumaar, Ph.D., Associate Director, Metabolomics Core, Buck Institute for Research on Aging, Novato, CA, USA
- Tong Shen, Ph.D., Project Scientist, West Coast Metabolomics Center, UC Davis, Davis, CA, USA
Opening Remarks: Nannan Tao, Ph.D., Application Manager MALDI, Bruker
Event Details:
- Date: September 10, 2026
- Time: 1:45 - 3:15 pm
- Location: Hub Room D
- Venue: University of California, 1 Shields Ave, Davis, CA, USA
Register Now for Our Activities at MANA
Register today and secure your spot at our Lunch Seminar and Interactive Workshop at MANA 2026.
Disclaimer
As you are certainly aware, special compliance regulations apply to public officials* and healthcare professionals** with regard to the event we are planning. If you accept our invitation, we will therefore assume that you will observe the compliance regulations that apply to you and that you have the necessary employer approval.
* Government Official means according the Bruker policies any of the following: any officer, employee or representative of a government (national, regional or local) entity, or any public agency, public authority, department or instrumentality thereof, regardless of their rank or title (e.g. a regulatory official or government inspector); any person working for or advising a government-owned or government-controlled enterprise (e.g. a professor at a government-owned university, or a purchaser at a government-owned hospital); any person working for or advising a national or international non-governmental organization (e.g. an employee of the Red Cross or The World Bank); any person performing a public function or providing a public service, even if that person works for a nongovernmental institution (e.g. private security personnel working in public functions); any person hired to review or accept bids for a government agency; any person with the responsibility to allocate or expend government funds; any person in a public law function, civil servant, judge or military personnel; any person acting for a political party, including party officials, candidates or individuals holding a position in a political party office; members of royal families; or immediate family members of any of the persons listed above. An immediate family member is a grandparent, parent, spouse, significant other, child, or sibling.
** A Healthcare Professional (HCP) is in accordance with the Bruker policies any physician, dentist, nurse, pharmacist or other individual who may prescribe, administer, purchase, dispense, recommend, or supply medical products or treatments or pharmaceutical products. In many cases, Bruker interacts with HCPs who work for state-owned hospitals (e.g. as medical scientists). These individuals will be classified as both HCPs and Government Officials.
Nur für die Forschung. Nicht für den Einsatz in klinischen diagnostischen Verfahren.