Microbial Identification

MALDI Biotyper® sirius RUO System | MALDI Biotyper® sirius GP System

The "sirius" solution for extended research capabilities for microbiology


MALDI Biotyper® sirius System

Bruker, being a global leader in MALDI-TOF technology, continuously invests in development and improvement of its instrument portfolio. As a result, this new "sirius" member of the MALDI Biotyper family has been launched in the scope of broadening research capabilities, including resistance detection applications.


Updated electronics | enabling further system improvements

The new Bruker MALDI Biotyper® sirius comprises the widely appreciated high capacity vacuum system of the MALDI Biotyper smart, as well as its fast 200 Hz smartbeam™ lifetime* laser. 

Developments in the electronics have expanded the system’s capabilities to allow for positive and negative ion detection.

  • Lighter: only 75 kg / 165 lbs
  • Faster target exchange
  • LED strip to remotely observe system status
  • Positive/negative ion mode 

All inherited, improved and new features of the MALDI Biotyper® sirius are held inside a true benchtop system of only 75 kg, allowing easy implementation in the lab. The system is fully compatible with existing MALDI Biotyper® software, libraries and consumables for microbial identification and beyond.

Daily laboratory life has been simplified by an LED strip on the front housing, conveniently allowing a visual system status check from a remote place in the lab.

* Lifetime meaning 7 years or 500 million shots, whichever comes first.

Positive/negative ion mode

Negative ion mode MALDI-TOF MS reveals the phosphoethanolamine modification of lipid A in colistin-resistant E. coli variants - With courtesy from Gerald Larrouy-Maumus, Imperial College, London-UK

Routine microbial identification is performed using positive ion mode only. The negative ion mode broadens the microbial research applications for the MALDI Biotyper® sirius, such as the analysis of lipids.

An exciting new MALDI-TOF lipidomics research topic is the rapid detection of colistin resistance related modifications to lipid A in colistin-resistant bacteria such as Acinetobacter baumanii¹ or Escherichia coli².

¹Dortet L et al., 2018, Scientific Reports, Vol: 8, ISSN: 2045-2322
²Dortet L et al., 2018, Journal of Antimicrobial Chemotherapy, Vol: 73, Pages: 3359-3367, ISSN: 0305-7453


For General Purpose use [In the United States, Japan and Taiwan: For Research Use Only (RUO)].

Not for use in clinical diagnostic procedures. Please contact your local representative for availability in your country.

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As of May 2021, Bruker Daltonik GmbH is now Bruker Daltonics GmbH & Co. KG.