Microbiology & Diagnostics

Sepsis and Resistance Testing

Rapid and accurate solutions to achieve fast identification and resistance detection from Positive Blood Cultures

Sepsis and Resistance Testing

The threat of multi-drug resistance (MDR) among gram-negative and gram-positive pathogens has increased worldwide over recent years, impacting both hospital and community acquired infections. Bruker is addressing the need for rapid and accurate solutions to achieve fast identification and resistance detection from Positive Blood Cultures (PBC).

During the last decade, the MALDI Biotyper® has revolutionized the microbial identification, offering a fast, easy, robust, reliable and cost-effective solution. As part of this product evolution, Bruker has focused efforts on finding novel solutions using the MALDI Biotyper® to shorten microbial identification and phenotypic resistance detection of carbapenemase and cephalosporinase, within 60-90 minutes after PBC alert.

After subculturing of the PBC, confirmation of resistance mechanisms and quantification of microbial resistance by determination of true MICs is performed using the MICRONAUT broth microdilution (BMD) product portfolio. MICRONAUT provides accurate, complete and true MIC of microorganisms as well as detection of important resistance mechanisms of Ambler class A (ESBL, KPC), class B (MBL), class C (AMP-C) and class D (OXA-48-like) cephalosporinases and/or carbapenemases.

Bruker have taken further developments to support resistance management by offering a real-time PCR kit to detect presence of the big 5 carbapenemase genes from a rectal swab, for patients who are at risk of colonization from Carbapenamase Producing Enterobacteriaceae (CPE).

MBT Sepsityper® IVD Kit

For direct pathogen identification from positive blood culture bottles within 15-20 minutes

MBT Sepsityper® Kit US IVD

For direct pathogen identification from positive blood culture bottles within 15-20 minutes.

MBT STAR®-Carba IVD Assay

The MBT STAR®-Carba IVD Kit allows rapid microorganism identification and detection of carbapenemase activity in one workflow

MBT STAR®-Cepha IVD Assay

The MBT STAR®-Cepha IVD Kit enables the detection of the characteristic enzymatic hydrolysis of the β-lactam ring of 3rd generation cephalosporin antibiotics.

MBT Subtyping IVD Module

The MBT Subtyping IVD Module combines the identification of important pathogens with automated subsequent detection of specific marker peaks, all in one workflow, for differentiation of closely related species or resistance marker detection.

Antimicrobial susceptibility testing

The MICRONAUT broth microdilution (BMD) product portfolio offers a broad range of antibiotic resistance and specialty antimicrobial susceptibility testing.

Carbaplex®

Carbaplex® IVD PCR kit is a multiplex real-time PCR test for the five most prevalent carbapenemase gene families; providing rapid results with high sensitivity and specificity without the need for culture. Carbaplex IVD PCR enables the rapid identification of Carbapenemase-producing Enterobacteriaceae (CPE) colonised patients.

Microbial Identification (GP + RUO)

The MALDI Biotyper® is an automated next generation microbial identification system based on matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry, and has become the method of choice for routine identification in clinical microbiology laboratories worldwide.

Hospital Hygiene

Advanced microbial strain typing, hospital hygiene and infection control solutions are improving the way hospitals deal with hospital acquired infections (HAI).

Molecular Diagnostics

Molecular diagnostics significantly impacts patient care and laboratory management, with rapid real-time PCR.

Microbial Identification for Clinical Laboratories (IVD-CE)

Unbiased and fast identification of microorganisms down to the species level, revolutionizing the analysis of microorganisms

Microbial Identification for Clinical Laboratories (US-IVD)

A key task in clinical microbiology is unbiased and fast identification of microorganisms down to the species level.