The MRMS technology is used in Metabolomics to study metabolites in plants, body fluids as well as in bacteria and yeast. MALDI Imaging is a technology that can be perfectly perform with high mass accuracy using the MRMS system. Imaging can be applied to human and animal tissue samples as well as plant samples. An overview of the literature of both technologies is shown here.
Title | Authors | Publication | Link |
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Olive Oil Quality and Authenticity Assessment Aspects Employing FIA-MRMS and LC-Orbitrap MS Metabolomic Approaches | T. Nikou et al. | Frontiers in Public Health 2020, Volume 8, Article 558226 | https://www.frontiersin.org/articles/10.3389/fpubh.2020.558226/full |
Expanding the Scope of Detectable Microbial Natural Products by Complementary Analytical Methods and Cultivation Systems | C. Bader et al. | J. Nat. Prod. 2021, 84, 2, 268–277 | https://pubs.acs.org/doi/10.1021/acs.jnatprod.0c00942 |
Chemical Fingerprinting of Conifer Needle Essential Oils and Solvent Extracts by Ultrahigh-Resolution Fourier Transform Ion Cyclotron Resonance Mass Spectrometry | O. O. Mofikoya et al. | ACS Omega 2020 5 (18), 10543-10552 | https://pubs.acs.org/doi/10.1021/acsomega.0c00901 |
Wine aging: a bottleneck story | T. Karbowiak et al. | npj Science of Food 3, 14 (2019) | https://www.nature.com/articles/s41538-019-0045-9 |
Wine microbiology is driven by vineyard and winery anthropogenic factors | C. Grangeteau et al. | Microbial Biotechnology (2017) 10(2), 354–370 | https://sfamjournals.onlinelibrary.wiley.com/doi/10.1111/1751-7915.12428 |
The chemodiversity of wines can reveal a metabologeography expression of cooperage oak wood | R. D. Gougeon et al. | PNAS 2009 106 (23) 9174-9179 | https://www.pnas.org/content/106/23/9174 |
A grape and wine chemodiversity comparison of different appellations in Burgundy: Vintage vs terroir effects | C. Roullier-Gall et al. | Food Chem. 2014, 152, 100-107 | https://www.sciencedirect.com/science/article/abs/pii/S0308814613016907 |
A Multilevel Study of Melon Fruit Reticulation Provides Insight into Skin Ligno-Suberization Hallmarks | H. Cohen et. al. | Plant Physiology, 179, 4, 2019, 1486–1501 | https://academic.oup.com/plphys/article/179/4/1486/6116732 |
Revisiting anabasine biosynthesis in tobacco hairy roots expressing plant lysine decarboxylase gene by using 15N-labeled lysine | S. Bunsupa et al. | Plant Biotechnol. 31(5): 511-518 (2014) | https://www.jstage.jst.go.jp/article/plantbiotechnology/31/5/31_14.1008a/_article |
Title | Authors | Publication | Link |
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Discrimination of Wine Attributes by Metabolome Analysis | A. Cuadros-Inostroza et al. | Anal. Chem. 2010, 82, 9, 3573–3580 | https://pubs.acs.org/doi/10.1021/ac902678t |
Unraveling different chemical fingerprints between a champagne wine and its aerosols | G. Liger-Belair et al. | PNAS, 2009, 106, 16545–16549 | https://www.pnas.org/content/106/39/16545 |
The chemodiversity of wines can reveal a metabologeography expression of cooperage oak wood | R. D. Gougeon et al. | PNAS, 2009, 106, 9174–9179 | https://www.pnas.org/content/106/23/9174 |
Exploring the chemical space of white wine antioxidant capacity: A combined DPPH, EPR and FT-ICR-MS study | R. Romanet et. al. | Food Chem. 355:129566 (2021) | https://www.sciencedirect.com/science/article/abs/pii/S0308814621005720 |
Hidden in its color: A molecular-level analysis of the beer’s Maillard reaction network | S. Pieczonka et. al. | Food Chem. 361:130112 (2021) | https://www.sciencedirect.com/science/article/abs/pii/S0308814621011183 |
On the Trail of the German Purity Law: Distinguishing the Metabolic Signatures of Wheat, Corn and Rice in Beer | S. Pieczonka et. al. | Front. Chem. 9:715372 (2021) | https://www.frontiersin.org/articles/10.3389/fchem.2021.715372/full |
Decomposing the molecular complexity of brewing | S. Pieczonka et. al. | npj Science of Food (2020) 4, 11 | https://www.nature.com/articles/s41538-020-00070-3 |
Determination of soyasaponins in Fagioli di Sarconi beans (Phaseolus vulgaris L.) by LC-ESI-FTICR-MS and evaluation of their hypoglycemic activity | G. Bianco et al. | Anal. Bioanal. Chem. 410, 1561–1569 (2018) | https://link.springer.com/article/10.1007/s00216-017-0806-8 |
In situ localization of micropollutants and associated stress response in Populus nigra leaves | C. Vilette et. al. | Environment International 126 (2019) 523–532 | https://www.sciencedirect.com/science/article/pii/S0160412018324917 |
Title | Authors | Publication | Link |
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Prenatal and Early Postnatal Cerebral d-Aspartate Depletion Influences l-Amino Acid Pathways, Bioenergetic processes, and Developmental Brain Metabolism | M. Grimaldi et al. | J. Proteome Res. 2021, 20, 1, 727–739 | https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00622 |
Ultrahigh-Resolution Mass Spectrometry-Based Platform for Plasma Metabolomics Applied to Type 2 Diabetes Research | Y. Zhu et al. | J. Proteome Res. 2021 20, 1, 463-473 | https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00510 |
Metabolomics Reveals Metabolic Biomarkers of Crohn's Disease | J. Jansson et al. | PLOS ONE 2009, 4, e6386 | https://journals.plos.org/plosone/article/metrics?id=10.1371/journal.pone.0006386 |
The compositional space of exhaled breath condensate and its link to the human breath volatilome | F. Moritz et al. | J. Breath Res. 9 027105 (2015) | https://iopscience.iop.org/article/10.1088/1752-7155/9/2/027105 |
Oral versus intravenous iron replacement therapy distinctly alters the gut microbiota and metabolome in patients with IBD | T. Lee et al. | Gut 2017;66:863–871 | https://gut.bmj.com/content/66/5/863 |
Dietary fat and gut microbiota interactions determine diet-induced obesity in mice | R. Kübeck et al. | Mol Metab. 2016 Oct 13;5(12):1162-1174 | https://www.sciencedirect.com/science/article/pii/S2212877816301892 |
Insulin Sensitivity Is Reflected by Characteristic Metabolic Fingerprints - A Fourier Transform Mass Spectrometric Non-Targeted Metabolomics Approach | M. Lucio et al. | PLOS ONE 2010, 5(10): e13317 | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013317 |
Title | Authors | Publication | Link |
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Direct injection Fourier transform ion cyclotron resonance mass spectrometric method for high throughput quantification of quinolones in poultry | L. E. Ikkere, et al. | Journal of Pharmaceutical and Biomedical Analysis 188 (2020) 113389 | https://www.sciencedirect.com/science/article/abs/pii/S0731708520312759 |
Combination of UHPLC-MS/MS-molecular networking approach and FTICR-MS for the metabolic profiling of Saccharomyces cerevisiae | O. Perruchon et al. | Journal of Pharmaceutical and Biomedical Analysis 195 (2021) 113857 | https://www.sciencedirect.com/science/article/abs/pii/S0731708520317441 |
Exploring yeast interactions through metabolic profiling | C. Roullier-Gall et al. | Sci Rep 10, 6073 (2020) | https://www.nature.com/articles/s41598-020-63182-6 |
DI-ICR-FT-MS-based high-throughput deep metabotyping: a case study of the Caenorhabditis elegans–Pseudomonas aeruginosa infection model | M. Witting et al. | Analytical and Bioanalytical Chemistry 407, 1059–1073 (2015) | https://link.springer.com/article/10.1007/s00216-014-8331-5 |
Marine sequestration of carbon in bacterial metabolites | O. J. Lechtenfeld et al. | Nature Communications 6, 6711 (2015) | https://www.nature.com/articles/ncomms7711 |
Comprehensive Analysis of the Alternaria Mycobolome Using Mass Spectrometry Based Metabolomics | M. Gotthardt et. al. | Mol. Nutr. Food Res. 2020, 64, 1900558 | https://onlinelibrary.wiley.com/doi/10.1002/mnfr.201900558 |
Title | Authors | Publication | Link |
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13C Isotope-Labeled Metabolomes Allowing for Improved Compound Annotation and Relative Quantification in Liquid Chromatography-Mass Spectrometry-based Metabolomic Research | P. Giavalisco et. al. | Anal. Chem. 2009, 81, 15, 6546–6551 | https://pubs.acs.org/doi/10.1021/ac900979e |
High-Resolution Direct Infusion-Based Mass Spectrometry in Combination with Whole 13C Metabolome Isotope Labeling Allows Unambiguous Assignment of Chemical Sum Formulas | P. Giavalisco et. al. | Anal. Chem. 2008, 80, 24, 9417–9425 | https://pubs.acs.org/doi/10.1021/ac8014627 |
Potential of dynamically harmonized Fourier transform ion cyclotron resonance cell for high-throughput metabolomics fingerprinting: control of data quality | B. Habchi et al. | Analytical and Bioanalytical Chemistry, 410, 483–490 (2018) | https://link.springer.com/article/10.1007%2Fs00216-017-0738-3 |
Ultrahigh resolution metabolomics for S-containing metabolites | R. Nakabayashi et. al. | Current Opinion in Biotechnology 2017, 43, 8–16 | https://www.sciencedirect.com/science/article/pii/S0958166916301604 |
An Enhanced Isotopic Fine Structure Method for Exact Mass Analysis in Discovery Metabolomics: FIA-CASI-FTMS | C. J. Thompson et al. | J. Am. Soc. Mass Spectrom. 2020, 31, 10, 2025–2034 | https://pubs.acs.org/doi/10.1021/jasms.0c00047 |
Title | Authors | Publication | Link |
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Lipid Dynamics due to Muscle Atrophy Induced by Immobilization | K. Kimura et al. | Journal of Oleo Science 2021, 70, 7, 937-946 | https://www.jstage.jst.go.jp/article/jos/70/7/70_ess21045/_article |
Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain | T. Vallianatou et al. | ACS Chemical Neuroscience 2021, 12, 10, 1811-1823 | https://pubs.acs.org/doi/10.1021/acschemneuro.1c00103 |
Ocular phenotypes in a mouse model of impaired glucocerebrosidase activity | M. Weber et al. | Scientific Reports 2021, 11, 1, 6079 | https://www.nature.com/articles/s41598-021-85528-4 |
GD3 synthase deletion alters retinal structure and impairs visual function in mice | C. A. Abreu et al. | Journal of Neurochemistry 2021, 158, 3, 694-709 | https://onlinelibrary.wiley.com/doi/10.1111/jnc.15443 |
Brain glycogen serves as a critical glucosamine cache required for protein glycosylation | R. C. Sun et al. | Cell Metabolism 2021, 33, 7, 1404-1417.e9 | https://www.cell.com/cell-metabolism/fulltext/S1550-4131(21)00220-5 |
Multimodal Imaging Mass Spectrometry of Murine Gastrointestinal Tract with Retained Luminal Content Shows Molecular Localization Patterns | E. R. Guiberson et al. | bioRxiv 2021, preprint | https://www.biorxiv.org/content/10.1101/2021.10.03.462819v1 |
Chelator sensing and lipopeptide interplay mediates molecular interspecies interactions between soil bacilli and pseudomonads | S. Andric et al. | bioRxiv 2021, pre-print | https://www.biorxiv.org/content/10.1101/2021.02.22.432387v2 |
Mass spectrometry imaging reveals glycine distribution in the developing and adult mouse brain | F. Eto et al. | Journal of Chemical Neuroanatomy 2020, 110, 101869 | https://www.sciencedirect.com/science/article/abs/pii/S0891061820301381 |
In situ metabolite and lipid analysis of GluN2D−/− and wild-type mice after ischemic stroke using MALDI MSI | W. T. Andrews et al. | Analytical and Bioanalytical Chemistry 2020, 412, 24, 6275-6285 | https://link.springer.com/article/10.1007%2Fs00216-020-02477-z |
In situ detection and imaging of lysophospholipids in zebrafish using matrix‐assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry | K. He et al. | Journal of Mass Spectrometry 2021, 56, 4, e4637 | https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jms.4637 |
Spatial Localization of Vitamin D Metabolites in Mouse Kidney by Mass Spectrometry Imaging | K. W. Smith et al. | ACS Omega 2020, 5, 22, 13430-13437 | https://pubs.acs.org/doi/10.1021/acsomega.0c01697 |
Mass spectrometry imaging reveals differential localization of natural sunscreens in the mantle of the giant clam Tridacna crocea | M. Goto-Inoue et al. | Scientific Reports 2020, 10, 1, 656 | https://www.nature.com/articles/s41598-019-57296-9 |
Localization of the lens intermediate filament switch by imaging mass spectrometry | Z. Wang et al. | Experimental Eye Research 2020, 198, 108134 | https://www.sciencedirect.com/science/article/abs/pii/S0014483520303924 |
Region-specific effects of Scrapper on the abundance of glutamate and gamma-aminobutyric acid in the mouse brain | F. Eto et al. | Scientific Reports 2020, 10, 1, 7435 | https://www.nature.com/articles/s41598-020-64277-w |
Mapping glucose metabolites in the normal bovine lens: Evaluation and optimisation of a matrix‐assisted laser desorption/ionisation imaging mass spectrometry method | A. Zahraei et al. | Journal of Mass Spectrometry 2021, 56, 4, e4666 | https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jms.4666 |
Spatial segmentation and metabolite annotation involved in sperm maturation in the rat epididymis by MALDI Imaging mass spectrometry | M. Lagarrigue et al. | Journal of Mass Spectrometry 2020, 55, 12, e4633 | https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/jms.4633 |
Imaging mass spectrometry to visualise increased acetylcholine in lungs of asthma model mice | T. Matsuda et al. | Analytical and Bioanalytical Chemistry 2020, 412, 18, 4327-4341 | https://link.springer.com/article/10.1007%2Fs00216-020-02670-0 |
A micrometer‐scale snapshot on phototroph spatial distributions: mass spectrometry imaging of microbial mats in Octopus Spring, Yellowstone National Park | L. Wörmer et al. | Geobiology 2020, 18, 6, 742-759 | https://onlinelibrary.wiley.com/doi/10.1111/gbi.12411 |
PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle | H. Yoon et al. | Cell Metabolism 2020, 32, 2, 215-228.e7 | https://www.cell.com/cell-metabolism/fulltext/S1550-4131(20)30318-1 |
A Global Cndp1-Knock-Out Selectively Increases Renal Carnosine and Anserine Concentrations in an Age- and Gender-Specific Manner in Mice | T. Weigand et al. | International Journal of Molecular Sciences 2020, 21, 14, 4887 | https://www.mdpi.com/1422-0067/21/14/4887 |
Nonclinical applications of quantitative whole-body autoradiography, and imaging mass spectrometry in drug discovery and development | E. G. Solon et al. | Progress in Biomedical Optics and Imaging 2020, Vol. 11219, 1121903-1121903-13 | https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11219/2551441/Nonclinical-applications-of-quantitative-whole-body-autoradiography-and-imaging-mass/10.1117/12.2551441.short |
Epilipidomics of Senescent Dermal Fibroblasts Identify Lysophosphatidylcholines as Pleiotropic Senescence-Associated Secretory Phenotype (SASP) Factors | M. Narzt et al. | Journal of Investigative Dermatology 2020, 141, 4, 993-1006.e15 | https://www.jidonline.org/article/S0022-202X(20)32367-8/fulltext |
Mass spectrometry imaging of blast overpressure induced modulation of GABA/glutamate levels in the central auditory neuraxis of Chinchilla | K. Zemaitis et al. | Experimental and Molecular Pathology 2021, 119, 104605 | https://www.sciencedirect.com/science/article/abs/pii/S0014480021000046 |
Title | Authors | Publication | Link |
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Unveiling spatial metabolome of Paeonia suffruticosa and Paeonia lactiflora roots using MALDI MS imaging | B. Li et al. | New Phytologist 2021, 231, 2, 892-902 | https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.17393 |
Analysis of Erythroxylum coca Leaves by Imaging Mass Spectrometry (MALDI–FT–ICR IMS) | N. A. dos Santos et al. | Journal of The American Society for Mass Spectrometry 2021, 32, 4, 946-955 | https://pubs.acs.org/doi/10.1021/jasms.0c00449 |
Sclareol and linalyl acetate are produced by glandular trichomes through the MEP pathway | C. Chalvin et al. | Horticulture Research 2021, 8, 1, 206 | https://www.nature.com/articles/s41438-021-00640-w |
High spatial resolution imaging of the dynamics of cuticular lipid deposition during Arabidopsis flower development | L. E. Alexander | Plant Direct 2021, 5, 4, e00322 | https://onlinelibrary.wiley.com/doi/10.1002/pld3.322 |
The metabolic environment of the developing embryo: A multidisciplinary approach on oilseed rapeseed | H. Rolletschek et al. | Journal of Plant Physiology 2021, 265, 153505 | https://www.sciencedirect.com/science/article/pii/S0176161721001449 |
The GORKY glycoalkaloid transporter is indispensable for preventing tomato bitterness | Y. Kazachkova et al. | Nature Plants 2021, 7, 4, 468-480 | https://www.nature.com/articles/s41477-021-00865-6 |
Spatial metabolomics using imaging mass spectrometry to identify the localization of asparaptine A in Asparagus officinalis | R. Nakabayashi et al. | Plant Biotechnology 2021, 38, 3, 311-315 | https://www.jstage.jst.go.jp/article/plantbiotechnology/38/3/38_21.0504b/_article |
A multimodal metabolomics approach using imaging mass spectrometry and liquid chromatography-tandem mass spectrometry for spatially characterizing monoterpene indole alkaloids secreted from roots | R. Nakabayashi et al. | Plant Biotechnology 2021, 38, 3, 305-310 | https://www.jstage.jst.go.jp/article/plantbiotechnology/38/3/38_21.0504a/_article |
Preserved and variable spatial‐chemical changes of lipids across tomato leaves in response to central vein wounding reveals potential origin of linolenic acid in signal transduction cascade | D. Veličković, et al. | Plant-Environment Interactions 2021, 2, 1, 28-35 | https://onlinelibrary.wiley.com/doi/10.1002/pei3.10038 |
Maize Zmcyp710a8 Mutant as a Tool to Decipher the Function of Stigmasterol in Plant Metabolism | S. I. Aboobucker et al. | Frontiers in Plant Science 2021, 12, 732216 | https://www.frontiersin.org/articles/10.3389/fpls.2021.732216/full |
Localization of mercury and gold in cassava (Manihot esculenta Crantz) | H. J. P. Alcantara et al. | Environmental Science and Pollution Research 2020, 27, 15, 18498-18509 | https://link.springer.com/article/10.1007%2Fs11356-020-08285-3 |
Unique and highly specific cyanogenic glycoside localisation in stigmatic cells and pollen in the genus Lomatia (Proteaceae) | E. Ritmejerytė et al. | Annals of Botany 2020, 126, 3, 387-400 | https://academic.oup.com/aob/article/126/3/387/5802779 |
An approach for broad molecular imaging of the root-soil interface via indirect matrix-assisted laser desorption/ionization mass spectrometry | D. Veličković et al. | Soil Biology and Biochemistry 2020, 146, 107804 | https://www.sciencedirect.com/science/article/abs/pii/S0038071720301012 |
Chemical characterization, antioxidant and antimicrobial activities of açaí seed (Euterpe oleracea Mart.) extracts containing A- and B-type procyanidins | G. R. Martins et al. | LWT 2020, 132, 109830 | https://www.sciencedirect.com/science/article/abs/pii/S0023643820308197 |
Differential distribution of characteristic constituents in root, stem and leaf tissues of Salvia miltiorrhiza using MALDI mass spectrometry imaging | S. Li et al. | Fitoterapia 2020, 146, 104679 | https://www.sciencedirect.com/science/article/abs/pii/S0367326X20302616 |
Rhizosphere microbiome mediates systemic root metabolite exudation by root-to-root signaling | E. Korenblum et al. | Proceedings of the National Academy of Sciences of the United States of America 2020, 117, 7, 3874-3883 | https://www.pnas.org/content/117/7/3874 |
Metabolomics should be deployed in the identification and characterization of gene‐edited crops | P. D. Fraser et al. | The Plant Journal 2020, 102, 5, 897-902 | https://onlinelibrary.wiley.com/doi/10.1111/tpj.14679 |
Title | Authors | Publication | Link |
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Secret messaging with endogenous chemistry | E. Kennedy et al. | Scientific Reports 2021, 11, 1, 13960 | https://www.nature.com/articles/s41598-021-92987-2 |
Mechanistic Insights Into Molecular Proxies Through Comparison of Subannually Resolved Sedimentary Records With Instrumental Water Column Data in the Santa Barbara Basin, Southern California | S. Alfken et al. | Paleoceanography and Paleoclimatology 2020, 35, 10, e2020PA004076 | https://agupubs.onlinelibrary.wiley.com/doi/10.1029/2020PA004076 |
An annually resolved record of Western European vegetation response to Younger Dryas cooling | I. Obreht et al. | Quaternary Science Reviews 2020, 231, 106198 | https://www.sciencedirect.com/science/article/pii/S0277379119311485 |
Moxidectin toxicity to zebrafish embryos: Bioaccumulation and biomarker responses | M. S. Muniz et al. | Environmental Pollution 2021, 283, 117096 | https://www.sciencedirect.com/science/article/abs/pii/S0269749121006783 |
Title | Authors | Publication | Link |
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MALDI Mass Spectrometry Imaging in a Primary Demyelination Model of Murine Spinal Cord | E. R. Sekera et al. | Journal of The American Society for Mass Spectrometry 2020, 31, 12, 2462-2468 | https://pubs.acs.org/doi/10.1021/jasms.0c00187 |
Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice | A. Aliluev et al. | Nature Metabolism 2021, 3, 9, 1202-1216 | https://www.nature.com/articles/s42255-021-00458-9 |
Targeted Expression of TGFBIp Peptides in Mouse and Human Tissue by MALDI-Mass Spectrometry Imaging | V. Anandalakshmi et al. | Separations 2021, 8, 7, 97 | https://www.mdpi.com/2297-8739/8/7/97 |
Identification of a distinct lipidomic profile in the osteoarthritic synovial membrane by mass spectrometry imaging | B. Rocha et al. | Osteoarthritis and Cartilage 2021, 29, 5, 750-761 | https://www.oarsijournal.com/article/S1063-4584(21)00038-8/fulltext |
Muscle metabolic remodelling patterns in Duchenne muscular dystrophy revealed by ultra-high-resolution mass spectrometry imaging | I. Dabaj et al. | Scientific Reports 2021, 11, 1, 1906 | https://www.nature.com/articles/s41598-021-81090-1 |
Integrative Metabolic Pathway Analysis Reveals Novel Therapeutic Targets in Osteoarthritis | B. Rocha et al. | Molecular & Cellular Proteomics 2020, 19, 4, 574-588 | https://www.mcponline.org/article/S1535-9476(20)35018-0/fulltext |
Maternal obesity alters placental lysophosphatidylcholines, lipid storage, and the expression of genes associated with lipid metabolism | K. L. Bidne et al. | Biology of Reproduction 2021, 104, 1, 197-210 | https://academic.oup.com/biolreprod/article/104/1/197/5922235 |
Title | Authors | Publication | Link |
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Reproducible Lipid Alterations in Patient-Derived Breast Cancer Xenograft FFPE Tissue Identified with MALDI MSI for Pre-Clinical and Clinical Application | V. Denti et al. | Metabolites 2021, 11, 9, 577 | https://www.mdpi.com/2218-1989/11/9/577 |
Mass spectrometry imaging of L-[ring-13C6]-labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma | J. Cao et al. | Cancer & Metabolism 2021, 9, 1, 26 | https://cancerandmetabolism.biomedcentral.com/articles/10.1186/s40170-021-00262-9 |
Metabolic tumor constitution is superior to tumor regression grading for evaluating response to neoadjuvant therapy of esophageal adenocarcinoma patients | A. Buck et al. | The Journal of Pathology, in print | https://onlinelibrary.wiley.com/doi/10.1002/path.5828 |
N-Glycosylation Patterns Correlate with Hepatocellular Carcinoma Genetic Subtypes | A. DelaCourt et al. | Molecular Cancer Research 2021, 19, 1868-77 | https://mcr.aacrjournals.org/content/19/11/1868 |
Metabolomic therapy response prediction in pretherapeutic tissue biopsies for trastuzumab in patients with HER2‐positive advanced gastric cancer | T. Kunzke et al. | Clinical and Translational Medicine 2021, 11, 9, e547 | https://onlinelibrary.wiley.com/doi/10.1002/ctm2.547 |
Patterns of carbon-bound exogenous compounds in lung cancer patients and association with disease pathophysiology | T. Kunzke et al. | Cancer Research 2021, in print | https://cancerres.aacrjournals.org/content/81/23/5862 |
Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence | G. Luis et al. | Redox Biology 2021, 43, 102006 | https://www.sciencedirect.com/science/article/pii/S2213231721001646 |
Tryptophan metabolism is inversely regulated in the tumor and blood of patients with glioblastoma | V. Panitz et al. | Theranostics 2021, 11, 19, 2021, 9217-9233 | https://www.thno.org/v11p9217.htm |
A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma | J. Choi et al. | Nature Metabolism 2021, 3, 2, 182-195 | https://www.nature.com/articles/s42255-021-00350-6 |
Imaging Mass Spectrometry and Lectin Analysis of N-Linked Glycans in Carbohydrate Antigen–Defined Pancreatic Cancer Tissues | C. T. McDowell et al. | Molecular & Cell Proteomics 2021, 20, 100012 | https://www.mcponline.org/article/S1535-9476(20)35126-4/fulltext |
Spatiotemporal heterogeneity of glioblastoma is dictated by microenvironmental interference | V. M. Ravi et al. | bioRxiv 2021, pre-print | https://www.biorxiv.org/content/10.1101/2021.02.16.431475v1 |
Slow TCA flux implies low ATP production in tumors | C. R. Bartman et al. | bioRxiv 2021, pre-print | https://www.biorxiv.org/content/10.1101/2021.10.04.463108v1 |
Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas | M. Friedrich et al. | Nature Cancer 2021, 2, 7, 723-740 | https://www.nature.com/articles/s43018-021-00201-z |
Glioblastoma multiforme: Metabolic differences to peritumoral tissue and IDH‐mutated gliomas revealed by mass spectrometry imaging | J. M. Kampa et al. | Neuropathology 2020, 40, 6, 546-558 | https://onlinelibrary.wiley.com/doi/10.1111/neup.12671 |
Defining the human kidney N-glycome in normal and cancer tissues using MALDI imaging mass spectrometry | R. R. Drake et al. | Journal of Mass Spectrometry 2020, 55, e4490 | https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jms.4490 |
Extracellular matrix alterations in low‐grade lung adenocarcinoma compared with normal lung tissue by imaging mass spectrometry | P. M. Angel et al. | Journal of Mass Spectrometry 2020, 55, 4, e4450 | https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jms.4450 |
MALDI-MSI spatially maps N-glycan alterations to histologically distinct pulmonary pathologies following irradiation | C. L. Carter et al. | Scientific Reports 2020, 10, Article number: 11559 | https://www.nature.com/articles/s41598-020-68508-y |
Zonal regulation of collagen‐type proteins and posttranslational modifications in prostatic benign and cancer tissues by imaging mass spectrometry | P. M. Angel et al. | The Prostate 2020, 80, 13, 1071-1086 | https://onlinelibrary.wiley.com/doi/10.1002/pros.24031 |
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Discovering New Lipidomic Features Using Cell Type Specific Fluorophore Expression to Provide Spatial and Biological Specificity in a Multimodal Workflow with MALDI Imaging Mass Spectrometry | M. A. Jones et al. | Analytical Chemistry 2020, 92, 10, 7079-7086 | https://pubs.acs.org/doi/10.1021/acs.analchem.0c00446 |
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For Research Use Only. Not for use in clinical diagnostic procedures.