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Emerging NMR Solutions for the Pharmaceutical Industry

In this virtual roundtable, experts explore the uses of nuclear magnetic resonance (NMR) in the pharmaceutical industry, aimed at addressing the role of NMR in the development and manufacture of small molecule and biological therapeutics.

Webinar Overview

Join us for a roundtable discussion with key players in the Pharmaceutical Industry, aimed at addressing the role of NMR in the development and manufacture of small molecule and biological therapeutics.

Opportunity to exchange knowledge and discuss applications on emerging NMR workflows. Dr Anna Codina Bruker will present an overview of NMR applications and the latest on hardware and software. Dr Lorraine Bateman, UCC will give an overview on how the ABCRF group is able to support the pharmaceutical industry with latest and innovative solutions.

Wednesday 24 November 2021

11:00 AM CET

Key Learnings

  • Why and how NMR is currently used in drug development and manufacturing
  • Advances in NMR solutions and role of benchtops
  • Challenges, opportunities and next steps

Speakers

Prof. Anita Maguire

Professor of Pharmaceutical Chemistry, School of Chemistry and School of Pharmacy, Director, ABCRF, UCC, SSPC Co-PI

Anita Maguire undertook undergraduate and postgraduate studies in Chemistry at UCC (B.Sc. 1985, Ph.D. 1989). Following postdoctoral research first at Namur, Belgium then at the University of Exeter, UK she returned to the Department of Chemistry in UCC in 1991, initially as a College Lecturer, then Associate Professor in Organic Chemistry in 2002, and was appointed in 2004 to the newly-established Chair of Pharmaceutical Chemistry, jointly in the Department of Chemistry and the School of Pharmacy, playing a leading role in development of the School of Pharmacy in recent years. Since her appointment at UCC she has played a strategic role in the development of teaching and learning, including the introduction of Medicinal and Pharmaceutical Chemistry at undergraduate level for the first time.

Over the past 30 years at UCC she has led an active research team focusing on synthetic organic and pharmaceutical chemistry, which interacts extensively with the pharmaceutical sector in Ireland and internationally. She is very committed to postgraduate education, ensuring the research students gain the skills required to underpin their future careers; 54 PhD and 6 MSc students have graduated from her research team since 1997, most of whom have developed careers within the pharmaceutical industry both in Ireland and internationally. In addition over 45 Postdoctoral Researchers have worked within the team, many of whom have progressed to careers in industry.

Dr. David Foley

Principal Scientist, Small Molecule Analytical Research and Development, Merck

David Foley received his PhD in organic chemistry from University College Cork, under the supervision of Prof. Anita Maguire. He then moved to the US, and conducted an industrial Postdoc at Lilly in Indianapolis where he developed flow NMR applications for reaction mechanism understanding. In 2011 he moved to Pfizer in Groton CT where he continued to advance the field of NMR reaction monitoring in the pharmaceutical industry. In 2017 he took on increased responsibilities as leader of the Structure Elucidation Group at Pfizer. In June 2021, he made the move to Small Molecule Analytical Research and Development at Merck & Co., Inc., Kenilworth, NJ, USA, where he is currently the analytical chemistry lead for a number of early and late phase programs.

Dr. Pat O'Neill

Chemistry Team Leader, Process Development Centre, Pfizer

Pat is the Chemistry Team Leader in the Pfizer Process Development Centre where he has been employed since 2004. The main remit of the PDC is the development of second generation API manufacturing processes when justified.

Prior to Pfizer, Pat worked in Schering-Plough as a research scientist and at a generic API manufacturing company at the start of his career, and has seen the entire gamut of API small molecule manufacturing.

Kevin O'Sullivan

Analytical Chemist, QCL Characterization, Eli Lilly

Kevin joined Lilly Kinsale in 2000. He has held a number of roles within the QCL department during this time. For the last 5 years he has been working as an Analytical Chemist within the Characterisation group. A primary focus as part of this role is the maintenance and development of NMR capabilities at Lilly Kinsale.

Dr. Ross Driver

Development Chemist, Pharmaceutical Development Services, Thermo Fisher Scientific

Ross completed his PhD and postdoctorate studies at Maynooth University, Co. Kildare with a focus on asymmetric organocatalytic transformations. Following this, he spent two years as a synthetic chemist in the research and fine chemicals custom synthesis field as part of Toronto Research Chemicals (now part of the LGC group). Following his return to Ireland, Ross joined Thermo Fisher Scientific as a development chemist at the Curraghbinny site. This role sees Ross working on early and late stage development projects for clinical and commercial manufacture of bulk API across a wide area of therapeutic use. Ross has extensive experience in the use of NMR for the structural elucidation of reaction products and impurities, reaction monitoring, REACH registration and reference standard qualification.

Dr. Anna Codina

Director Pharmaceutical Business Unit, Bruker BioSpin

Anna has a degree in Chemistry and a PhD in Protein NMR from the University of Barcelona, Spain. She undertook her post-doc in protein NMR at the MRC Laboratory of Molecular Biology in Cambridge, UK, and following that worked in the Analytical R&D department of Pfizer for eight years, becoming proficient in low level impurity structure elucidation, reaction monitoring, qNMR and the preparation of regulatory documentation.

She received a Pfizer Worldwide Achievement Award for the implementation of reaction monitoring by NMR in an open access environment.

She joined Bruker in 2011 as Material Characterisation Laboratory Manager and she is now the Director of the Pharmaceutical Business Unit at Bruker BioSpin.

Dr. Sukhvinder Chohan

European Business Development Manager - Biopharm & Pharma

Experienced sales professional with excellent demonstrated history of business development in the pharmaceuticals industry. Skilled in Negotiation, Chemistry, Customer Service, Sales, and Life Sciences. Strong polymer chemist professional graduated from Aston University, with a PhD in Biodegradable Polymers.

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