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In this webinar, Dr. Lizzie Manning shares her work using miniscopes and the Sapap3 knockout mouse model to provide new data on obsessive-compulsive disorder.
In this webinar, I discuss my use of miniature microscopes to better understand the neural circuitry and underlying functions of obsessive-compulsive (OCD) behaviors. I provide examples of challenges and opportunities, based on my experience using the Sapap3 knockout mouse model, which is currently the most widely used model system for OCD research. I also show how distinct changes in flexible behaviors relevant to OCD were imaged using miniature microscopes.
Lizzie Manning, Ph.D., Lecturer and Researcher Associate, School of Biomedical Sciences and Pharmacy, University of New Castle