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Preclinical neuroimaging in Alzheimer’s and neurodegenerative diseases
Webinar Overview
The focus of Yu-Chien Wu’s research program is to develop innovative MRI neuroimaging technologies for elucidating disease mechanisms, facilitating early diagnoses, and identifying optimal treatments. To this end, she obtained funding from NIA and NINDS as a PI to study alterations in living human brains due to Alzheimer’s disease (AD) and sport-related concussion. In addition to her own research program, she participates in many projects as a co-investigator, supporting neuroimaging protocol design, image processing, and data analyses.
She has a long history of applying advanced diffusion compartment imaging techniques to study microstructural changes in the human brain with AD and their clinical utilities for predicting cognitive outcomes, blood biomarkers, and A-beta and tau-PET imaging. Recently, her research program extended to preclinical imaging in rodent models of human diseases, including AD. She directs the In-Vivo Imaging Core and Roberts Translational Imaging Facility at the Indiana University School of Medicine (IUSM). The Imaging Core is equipped with research dedicated clinical 3T MRI scanners, PET-CT scanners, and a 9.4T PET-MRI scanner for small animal imaging. She also co-leads the neuroimaging core of the Indiana Alzheimer’s Disease Research Center (IADRC).
On Demand Session
Speaker
Dr. Yu-Chien Wu
Adjunct Associate Professor
Weldon School of Biomedical Engineering at Purdue University, Lafayette, IN, USA and Co-Director of Neuroimaging Core at the Indiana Alzheimer's Disease Research Center, Indianapolis IN, USA
