3D X-ray Microscopy (XRM)

SKYSCAN 1272 CMOS Edition

High-resolution 3D X-ray Microscopy

A sharp 3D view of your sample


0.6 m²
A desktop system that fits in every lab
External sample changer
Unattended high-throughput analysis
Detector technology
High contrast images

SKYSCAN 1272 CMOS – High-resolution XRM

SKYSCAN 1272 CMOS Edition builds on the trusted SKYSCAN 1272 desktop X-ray Microscopy platform and incorporates the latest X-ray technologies to bring XRM to the next level.


The state-of-art 16 megapixels CMOS X-ray detector provides high-contrast images with superior resolution. The extended detector field of view and enhanced sensitivity for X-rays result in up to twice shorter scan times.


The SKYSCAN 1272 CMOS offers automatic selection of parameters with Genius-Mode. Magnification, energy, filter, exposure time and background corrections can all be optimized automatically with a single click.


A 16-position sample changer is optionally available for unattended high throughput scanning.

SKYSCAN 1272 CMOS is complemented by 3D.SUITE. This comprehensive software suite covers GPU-accelerated reconstruction, 2D/ 3D morphological analysis, as well as surface and volume rendering visualization.

Key Features

SKYSCAN 1272 CMOS Features

Genius Mode

The SKYSCAN 1272 CMOS offers automatic selection of parameters with Genius-Mode. Magnification, energy, filter, exposure time and background corrections can all be optimized automatically with a single click.

Furthermore, both the sample and large-format CMOS camera can be positioned as close as possible to the source, which substantially increases the measured intensity. That is why SKYSCAN 1272 CMOS scans up to 5 times faster compared to conventional systems with fixed camera position.

SKYSCAN 1272 CMOS Features

Sample changer

SKYSCAN 1272 CMOS can optionally be equipped with an external 16-position sample changer to increase throughput for QC and routine analysis.

The sample changer accepts a variety of sample sizes, up to a diameter of 25 mm.

Samples can be can be easily replaced at any time without interrupting an ongoing scanning process. New samples are automatically detected, and LED‘s indicate the status for every scan: ready, scanning, done.


SKYSCAN 1272 CMOS Features

In-situ stages

The Bruker material testing stages are designed to perform compression experiments up to 4400 N and tensile experiments up to 440 N. All stages automatically communicate through the system’s rotation stage, without the need of any cable connections. Using the supplied software, scheduled scanning experiments can be set up.

Bruker's heating and cooling stages can reach temperatures of up to +80ºC, or 30ºC below ambient temperature. Just like the other stages, no extra connections are needed, and there is an automatic recognition of the stage. Using the heating & cooling stages, samples can be examined under non-ambient conditions, to evaluate the effect of temperature on the sample’s microstructure.


No external cooling water or special power with no compromise in performance: Designed for the ecological and economical needs of today


Smart solutions and design, such as the integrated vibration isolation, form a perfect whole

Highlighted Applications


Fibers and Composites

Volume rendering of an FFP2 mask, fibers are color coded by the local orientation

By combining materials into a composite the resulting component can have increased strength while significantly decreasing weight. Further optimization comes from ensuring the orientation of the subcomponents are optimized. One of the classic components used are fibers ranging from steel rebar in concrete, glass fibers in electronic components, to carbon nanotubes in aviation materials. XRM allows inspection of fibers and composites without the need for cross sectioning, ensuring the condition of the sample is not affected by sample preparation.

  • Orientation of embedded objects
  • Quantification of layer thickness, fiber sizes and separation
  • In-situ temperature and physical properties testing with accessory stages


A pharmaceutical drug for oral medication under form of enteric-coated granules, pixel size of 0.45 µm. The coating consists of three layers, the outer layer is color-coded for the thickness.

Development of a new pharmaceutical is a time consuming and costly endeavor. XRM can accelerate time-to-market by providing immediate feedback on the product’s internal structure during the product formulation stage.

  • Determine the table compaction density
  • Measure coating thickness uniformity
  • Evaluate API distribution
  • Detect stress induced micro-cracks in compacted tables
  • Apply in-situ compression for testing the mechanical properties


Multivolume image of the reconstructed data and a color-coded structure separation showing both the diameter of the foam cells as well as the hollow character of the struts of an open-cell nickel foam. 1.0 µm pixel size.

Foams are widely used for industrial applications. Whether they are used as thermal or acoustic insulators, shock absorbers in protective parts, filters … depends on the material and the structural properties of the foam.
XRM enables to visualize a foam’s 3D internal structure in a non-destructive way.

  • Determine the structural thickness of local struts
  • Determine the structure separation to visualize the pore network
  • Apply in-situ mechanical tests with compression and tensile stages
  • Quantify the level of open and closed porosity

SKYSCAN 1272 CMOS Specifications




X-ray source

40 – 100 kV

10 W

< 5 µm spot size at 4 W

Maintenance-free sealed X-ray source

Fast scans for QC, or 4D XRM

X-ray detector

16 MP sCMOS detector (4096 x 4096 pixels)

Fine-pitched detectors for achieving highest resolution

Object size

75 mm diameter

80 mm height

Capable to scan from small to medium large sample sizes

Sample changer


16 samples up to 25 mm diameter

External access

Unattended high throughput

Any combination of large and small samples

Add/remove samples at any time without interrupting the actual scan


W 1160 mm x D 520 mm x H 330 mm

Weight 150 kg

Space-saving desktop system that fits in every lab

Power supply

100-240V AC, 50-60Hz, 3A max.

Minimum installation requirements, a standard power supply suffices


Bruker XRM solutions include all software needed to collect and analyze data. An intuitive graphical user interface with user guided parameter optimization support both expert and novice users. By using the latest GPU powered algorithms, reconstruction time is substantially reduced. CTVOX, CTAN and CTVOL combine to form a powerful suite of software for both qualitative and quantitative analysis of models.

Measurement Software:
SKYSCAN 1272 – Instrument control, measurement planning and collection

Reconstruction Software:
NRECON – Transforms the 2D projection images into 3D volumes

Analysis Software:
DATAVIEWER – Slice-by-slice inspection of 3D volumes and 2D/3D image registration
CTVOX – Realistic visualization by volume rendering
CTAN – 2D/3D image analysis & processing
CTVOL – Visualization of surface models to export for CAD or 3D printing

Service & Support