Molecular Diagnostics

FluoroType® Mycobacteria VER 1.0

Powered by LiquidArray® | Next generation multiplexing
Next generation multiplexing

LiquidArray® powering differentiation of nontuberculous mycobacteria (NTM)

Next generation multiplexing
Differentiation of 32 clinically relevant nontuberculous mycobacteria and detection of MTB complex in a single well
LiquidArray® technology
Pioneering PCR-based technology enables high level multiplex analysis to provide comprehensive coverage
Streamlined workflow
Reliable infectious disease diagnostics from positive culture to results at a glance in 2.5 hours
Results at a glance
Automated interpretation by FluoroSoftware® XT-IVD provides user-friendly, easy-to-interpret reporting

Differentiation of nontuberculous mycobacteria and detection of MTB complex powered by LiquidArray®

Nontuberculous mycobacteria (NTM) are environmental bacteria commonly found in soil and water throughout the world. They can cause opportunistic infections whose treatment and its duration vary depending on the NTM species causing the infection. Therefore, identification of mycobacteria at the species level is of great clinical relevance. As the symptoms of an NTM infection vary greatly from person to person and can mimic other diseases, a correct diagnosis is often delayed, leading to progressive worsening of the condition and irreversible organ damage. Consequently, rapid and reliable identification of clinically relevant NTMs is essential for effective disease management.

The FluoroType® Mycobacteria VER 1.0 assay offers reliable detection and differentiation of 32 clinically relevant NTM species in a single well. The molecular genetic assay is powered by the innovative LiquidArray® technology, providing high level multiplexing capabilities. The test allows detection of the Mycobacterium tuberculosis complex alongside identification of 32 specific NTMs, including M. avium, M. kansasii and the different subspecies of the M. abscessus complex. Moreover, additional mycobacterial species are detected at genus level.

Starting with DNA extraction from a positive culture and PCR set-up, amplification and detection are performed by the FluoroCycler® XT. The FluoroSoftware® XT-IVD generates results at a glance, in an easy to use, easy to interpret test report. The streamlined workflow allows NTM determination in just 2.5 hours making the FluoroType® Mycobacteria VER 1.0 assay an indispensable tool for diagnosis of NTMs.

Fast and reliable NTM detection and differentiation

Reliable and rapid differentiation between NTM species is essential for determination of treatment courses, which are species-dependent. The FluoroType® Mycobacteria VER 1.0 assay enables molecular testing of specific NTMs from an extensive set of NTM species in a single well. Providing comprehensive coverage can reduce delays in diagnosis and mitigate the risk of incorrect treatment regimens and unnecessary patient health deterioration.

FluoroType Mycobacteria® VER 1.0 - powered by LiquidArray® - provides detection of these NTMs in one well.

Mycobacterium abscessus subsp. abscessus

Mycobacterium abscessus subsp. bolletii

Mycobacterium abscessus subsp. massiliense

Mycobacterium asiaticum

Mycobacterium avium

Mycobacterium celatum

Mycobacterium chelonae

Mycobacterium chimaera

Mycobacterium fortuitum

Mycobacterium gastri

Mycobacterium genavense

Mycobacterium goodii

Mycobacterium gordonae

Mycobacterium haemophilum

Mycobacterium heckeshornense/Mycobacterium xenopi*

Mycobacterium intermedium

Mycobacterium interjectum

Mycobacterium intracellulare

Mycobacterium kansasii

Mycobacterium lentiflavum

Mycobacterium malmoense

Mycobacterium marinum

Mycobacterium mucogenicum

Mycobacterium peregrinum

Mycobacterium phlei

Mycobacterium scrofulaceum

Mycobacterium shimoidei

Mycobacterium simiae

Mycobacterium smegmatis

Mycobacterium szulgai

Mycobacterium ulcerans

Mycobacterium xenopi

* Detection signature for M. heckeshornense is similar to that of M. xenopi. While M. xenopi can be reliably identified, specific determination of M. heckeshornense is not possible.

Powered by LiquidArray®

LiquidArray® from Bruker is a next generation multiplexing PCR-based technology. It is underpinned by the unique features of the FluoroCycler® XT – Bruker’s high performance thermocycler. With precise temperature control and no optical cross-talk or colour compensation, assays are designed with a high number of targets per optical channel. LiquidArray® assays are automatically interpreted and reported providing advanced multiplex results at a glance in a familiar, easy to use format.

LiquidArray® brings next generation multiplexing for infectious disease diagnostics to the routine clinical microbiology laboratory.

Streamlined workflow from sample to result

Starting from positive culture, FluoroLyse is used for DNA extraction and is followed by PCR set-up with FluoroType® Mycobacteria VER 1.0. An internal control is included in each reaction to ensure reliability and validity of results. LiquidArray® amplification and detection is performed with the FluoroCycler® XT and the integrated FluoroSoftware® XT-IVD software provides results at a glance.


Please contact your local representative for availability in your country.

Not for sale in the USA.

Legal Manufacturer is Hain Lifescience GmbH – A Bruker Company