Preclinical Micro-CT


Automated push-button micro-CT screening of mineralized and soft tissue samples, teeth, plants and insects

Ultimate Ease-of-Use


0.7 m²
A desktop system that fits in every lab
External sample changer
Unattended high-throughput analysis
From scan to result with a single click
Easy operation for routine applications

The desktop SKYSCAN 1275 is a real 3D X-ray microscopy power pack, designed for fast scanning of a wide range of samples. Thanks to the compact geometry and fast flat-panel detector the time to result can be as short as a few minutes. Just ideal for high throughput imaging.

The SKYSCAN 1275 comes furthermore with a high level of automation thus providing superior ease-of-use. Simply pushing the button at the control panel starts an auto-sequence of a fast scan, followed by reconstruction and volume rendering. All executed while the next sample is already being scanned. The optional 16-position sample changer even allows for unattended high throughput scanning.

The SKYSCAN 1275 is complemented by 3D.SUITE. This extensive software suite covers GPU-accelerated reconstruction, 2D/ 3D morphological analysis, as well as surface and volume rendering visualization.

Just Start your analysis

Key Features

SKYSCAN 1275 Features

Push-Button XRM

Just insert a sample, manually or automatically, and get a complete 3D volume without any further interaction.
Push-Button XRM includes everything: automatic sample size detection, sample scanning, 3D reconstruction, and 3D volume rendering. Ideal for routine tasks, or operation by non-expert users!
You need full control? No problem, SKYSCAN 1275 offers all features.
Combined with a sample changer SKYSCAN 1275 even works 24/7.

SKYSCAN 1275 Features

Sample changer

SKYSCAN 1275 can optionally be equipped with an external 16-position sample changer to increase throughput for QC and routine analysis.
The sample changer accepts a variety of sample sizes, up to a diameter of 96 mm.
Samples can be can be easily replaced at any time without interrupting an ongoing scanning process. New samples are automatically detected, and LED‘s indicate the status for every scan: ready, scanning, done.

SKYSCAN 1275 Features

In-situ stages

The Bruker material testing stages are designed to perform compression experiments up to 4400 N and tensile experiments up to 440 N. All stages automatically communicate through the system’s rotation stage, without the need of any cable connections. Using the supplied software, scheduled scanning experiments can be set up.

Bruker's heating and cooling stages can reach temperatures of up to +80ºC, or 30ºC below ambient temperature. Just like the other stages, no extra connections are needed, and there is an automatic recognition of the stage. Using the heating & cooling stages, samples can be examined under non-ambient conditions, to evaluate the effect of temperature on the sample’s microstructure.

Highlighted Applications

Bone Applications

The SKYSCAN 1275 provides the bone research community with a solid solution for fast, high throughput and high-quality bone morphometry of animal models. The advanced cMOS flat panel camera cuts rodent morphometry scans to a tiny fraction of what scientists are used to with the first generation of osteoporosis research microCT scanners – we’re talking about 5 minutes only. Without compromise to resolution of the smallest rod-like mouse trabecular structures – nothing is lost. With the SKYSCAN 1275 you will publish more papers each year than with scan-slow microCT alternatives. 

  • Fast cMOS flat panel with ~2000 x 1500 pixel format, fastest scans less than 100 seconds (step and shoot). 
  • Effortless imaging of large bone samples not previously studied by microCT with fast throughput for research productivity.
  • All rodent morphometry of trabecular and cortical bone is taken care of, with bone morphometry (ASBMR nomenclature) with comprehensive 3D and 2D parameters, and densitometry including BMD calibration references over a 2-32mm diameter size range. 
  • Optional sample changer for 16 preloaded samples makes large scale screening studies possible with thousands of mouse or zebrafish bones for trabecular and cortical bone parameters. 


Teeth are a step up from rodent bones in thickness and mineral density, requiring an appropriate microCT solution. The SKYSCAN 1275 is this solution, effortlessly imaging small and large teeth, even fossil ones subject to mineral diagenesis. And this capability in a user-friendly high-throughput desktop instrument. With the SKYSCAN 1275 you will publish more papers each year than with scan-slow uCT alternatives. 

  • Fast cMOS flat panel with ~2000 x 1500 pixel format, fastest scans less than 100 seconds (step and shoot). 
  • The large x-ray camera with excellent high energy sensitivity makes most vertebrate teeth scannable as well as prostheses and dental implant materials.
  • Optional sample changer for 16 preloaded samples makes large scale dental screening and endodontic before-and-after canal treatment studies straightforward.
  • Bone morphometry (ASBMR nomenclature) with comprehensive 3D and 2D parameters, with densitometry including BMD calibration references over a 2-32mm diameter size range. 

Plant and Animal Biology

MicroCT is exceptionally good at visualization of the finest details of the internal structure of biological tissue. It is already a well-established tool in botany and zoology. The SKYSCAN 1275 is a unique compact and user-friendly desktop scanner with a powerful flat panel camera allowing – in a nutshell – faster scanning of bigger samples than before. Its fast, user-friendly scanning with a large field of view removes barriers to the advantageous use of this non-destructive 3D imaging technique to more and more scientists and disciplines.

  • Fast evaluation of the internal structures of fruits, seeds, insects, corals and marine organisms.
  • Digitize a 3D volume of valuable samples for further visualization or cataloging.
  • Multiple sample scanning possible due to the batch-scanning mode and optional sample changer, effectively reducing down-time. 
  • Comprehensive 3D image analysis capability including morphometry and densitometry, 3D registration, segmentation and advanced image processing methods.

SKYSCAN 1275 Specifications




X-ray source

40 – 100 kV

10 W

< 5 µm spot size at 4 W

Maintenance-free sealed X-ray source

Fast scans for QC, or 4D XRM

X-ray detector

Active pixel CMOS flat-panel

3 MP (1944 x 1536)

75 µm pixel size

Excellent signal-to-noise

Large Field-of-View

Object size

96 mm diameter

120 mm height

Capable to scan a large range of sample sizes

Sample changer


16 samples up to 50 mm diameter

8 samples up to 96 mm diameter

External access

Unattended high throughput

Any combination of large and small samples

Add/remove samples at any time without interrupting the actual scan


W 1040 mm x D 665 mm x H 400 mm

Weight 170 kg

Space-saving desktop system that fits in every lab

Power supply

100-240V AC, 50-60Hz, 3A max.

Minimum installation requirements, a standard power supply suffices


Bruker XRM solutions include all software needed to collect and analyze data. An intuitive graphical user interface with user guided parameter optimization support both expert and novice users. By using the latest GPU powered algorithms, reconstruction time is substantially reduced. CTVOX, CTAN and CTVOL combine to form a powerful suite of software for both qualitative and quantitative analysis of models.

3D.Suite Software:
Bruker microCT solutions include our comprehensive, in-house developed 3D.SUITE software for reconstruction, inspection, visualization, and analysis of the internal object structure

Measurement Software:
SKYSCAN 2214 – Instrument control, measurement planning and collection

Reconstruction Software:
NRECON – Transforms the 2D projection images into 3D volumes

Analysis Software:
DATAVIEWER – Slice-by-slice inspection of 3D volumes and 2D/3D image registration

CTVOX – Realistic visualization by volume rendering

CTAN – 2D/3D image analysis & processing

CTVOL – Visualization of surface models to export for CAD or 3D printing

SKYSCAN 1275 - Service & Support

Available services include

  • Help desk support from highly-skilled troubleshooting professionals, to isolate and resolve hard- and software problems
  • Web-based remote instrument service for service diagnosis and applications support
  • Merged reality support with Help Lightning – a virtual engineer at your side (video)
  • Planned maintenance, according to your requirement
  • Customer on-site repair and maintenance service
  • Spare parts availability typically over night or within a few working days worldwide
  • Compliance services for installation qualification, operational qualification / performance verification
  • Site planning and relocation

Bruker Support

On our support website you will find:

Software Updates 

  • System software updates are available online to registered users.


  • Product manuals and installation guides are available online to registered users.


Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging

Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory