BioSpec Ultra-High Field MRI

The Ultimate in Preclinical MRI

Cutting edge

Sensitivity and resolution

Ultimate preclinical MRI
Unparalleled sensitivity
1000 mT/m
Highest resolution with gradient strength up to 1000 mT/m
Groundbreaking Research
Made possible only via the physical effects of ultra-high field
BioSpec Brochure

The ultimate in preclinical MR imaging is made possible with Bruker’s ultra-high field BioSpec instruments. These instruments are the highest commercially available preclinical MRI instruments with field strenghts of 11.7 Tesla, 15.2 Tesla, and 18 Tesla. These instruments offer non-paralleled SNR for in vivo imaging allowing groundbreaking research whether it be addressing fundamental questions or treatment of diseases. Combined with MRI CryoProbes, they deliver highest spatial resolution in-vivo. In addition to increased sensitivity, the reasons for choosing an ultra-high-field instrument include higher magnetic susceptibility and increased spectral dispersion and the novel studies that are thus enabled.

Scalable AVANCE NEO electronics enabling both MRI and MRS applications and incorporating up to 16 receiver channels

  • Real-time spectrometer control for optimization of acquisition parameters during scan
  • Highest performance gradients with highest amplitudes and slew rates, shim strengths and duty cycles
  • Extensive RF coil portfolio for mice and rats available, including coils for head, brain, cardiac, body, x-nuclei and multipurpose applications
  • MRI CryoProbe™  delivering an exceptional increase in sensitivity
  • ParaVision® 360: intuitive software package, for multi-dimensional MRI/MRS data acquisition, visualization, reconstruction, and analysis
  • In-house development and production of all key components (software, magnet, gradient, spectrometer, RF-coils) ensures the best performance and short repair times


February 16, 2017

Metabolic Imaging in Neurodegenerative Disease using CEST MRI

This webinar will emphasize the significance of CEST in studying neurodegenerative diseases such as Alzheimer's and Huntington's diseases, conditions and also spinal cord disorders.
October 11, 2017

In Vivo Magnetic Resonance Imaging

In this webinar, medical physicist Prof. Volker Rasche (University Hospital Ulm, Germany) and Bruker’s MRI product specialist Dr. Thomas Basse, will discuss how in ovo MRI can be used to non-invasively monitor contrast agent-labelled compounds in CAM models of transplanted tumor cells.
December 14, 2017

New insights into brain function

In this webinar, MR physicist Professor Seong-Gi Kim and market product manager Tim Wokrina from Bruker BioSpin will discuss how CEST imaging significantly benefits from ultra-high fields.
November 29, 2018

Using High Fields to Combat Ischemic Stroke with Cell Therapy

In this webinar, Prof. Samuel Grant, researcher at the National High Magnetic Field Laboratory and FAMU-FSU College of Engineering in Florida, will gi
Ultra-high field MR
October 10, 2019

Use of ultra-high field MRI for in and ex vivo neuroimaging

Use of ultra-high field MRI for in and ex vivo neuroimaging
Quantification and application of CEST signals in rodent brain
On Demand Session

Quantification and application of CEST signals in rodent brain

Dr. Zhang then elaborates on his contributions to these goals using his BioSpec 11.7 T, focusing on CEST quantification, which he uses for early stroke detection and in combination with pH guided surgeries.
When Instruments Drive Science: From single neuron diffusion fMRI to GlucoCEST fMRI at 17T
On Demand Session

When Instruments Drive Science: From single neuron diffusion fMRI to GlucoCEST fMRI at 17T

Prof. Denis Le Bihan has played a substantial role in the initiation and development of diffusion imaging in MRI. In his talk, he takes us on an historical tour of diffusion imaging, explaining how he performs diffusion-based fMRI, and culminating with his most recent discoveries using GlucoCEST fMRI.
Quantification and application of CEST signals in rodent brain
On Demand Session

Animal brain MRI in Ultra-High Field

Hao Huang begins his talk with an overview of the dimensions of mouse, macaque, and human brains and a demonstration of how high magnetic fields make similar resolutions possible at all animal models.
Mouse fMRI at Ultrahigh fields
On Demand Session

Mouse fMRI at Ultrahigh Fields

Seong-Gi Kim, who makes use of both a BioSpec 9.4 T and a BioSpec 15.2 T, details his fMRI work, expanding on anesthesia considerations, comparing the two field strengths, and sharing exciting discoveries made possible at with the BioSpec 15.2 T.
Where high fields matter: Investigating the Brain at Multiple Levels of Organization
On Demand Session

Where high fields matter: Investigating the Brain at Multiple Levels of Organization

Klaus Scheffler provides an overview of the different levels of structural and functional organization of the brain and which imaging modalities cover which levels at which resolutions, demonstrating that higher field MRIs can probe finer levels of structural and temporal organization.
CEST Atlanta

Chemical Exchange Saturation Transfer (CEST) imaging Expert Series

We welcome you to an exclusive webinar series with experts from around the world. Kannie Chan, Steffen Goerke, Mike McMahon, and Daisy Villano met virtually to discuss the facets of CEST that they each will present, so that their talks perfectly complement each other.


Translation Research - From Preclinical to Clinical MRI


Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging

Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory