Preclinical MRI

ParaVision 360

Most advanced preclinical imaging software

Consistent Quantification

Intuitive Use

Consistent Quantification
Highest accuracy in all research stages, from set-up to quantification, from day to day, and from subject to subject leads to the most consistent, reliable data
Greatest Imaging Power
Extensive and innovative range of methods combined with sophisticated viewing, reconstruction, and analysis tools provide the most information from imaging subjects
Seamless Multimodal Imaging
Uniformity across MRI, PET, and µCT for intuitive use
ParaVision 360 Brochure

Focusing on consistent quantification, ParaVision 360 makes scanning even more intuitive, while maintaining the full flexibility that Bruker users praise. The enlarged MRI sequence portfolio, which is exclusive to Bruker, and the powerful image data evaluation functions lead to maximum proficiency in scanning and analysis, while the simplicity and uniformity across the range of instrumentation allows operators to put their focus on their research.

ParaVision 360 V3.5 is now available

Highlights from the newest features of the 3.5 release:

Out of the Box Protocols for Morphological, Metabolic, and Molecular Studies

  • Fast, T2-weighted 3D, isotropic in vivo imaging with RAREvfl
  • Standardized rat T2* EPI protocol for fMRI meeting guidelines of the MultiRat1 collaboration
  • Fully automated PET/CT stitched protocol including attenuation correction (AC) map for rats up to 250 mm in length


Fast extended PET/CT imaging for full rat body coverage

Extended Spectroscopy Capabilites

  • Spectral editing of J-coupled resonances such as lactate, γ-aminobutyric acid (GABA), glutamate, and glx (glutamate/glutamine) with MEGA-PRESS
  • Efficient visualization and processing of single voxel spectroscopy and chemical shift imaging spectroscopic data (e.g. CSI) with Spectroscopy Card
  • Metabolic map creation and anatomical reference image overlaying
  • AI based baseline and phase correction
CSI with NAA frequency mapped

Efficient PET Scanning

  • Real-time 3D display of tracer biodistribution during scanning
  • Data display on touchscreen as well as in pre-defined single slices for fastest planning of further scans based on tracer biodistribution
Touchscreen display of count rate evolution and MIP online reconstruction

Cross-modality Highlights

  • Common terminology between instruments, common integrated multimodal workflows, and common image processing, viewing, and analysis tools and functionalities for optimal clarity
  • Animal Transport System control via touchscreen1
  • Multi-station image acquisition and imaging stitching1
  • Simple selection of prone or supine viewing
  • Automatic 3D image fusion
  • MR Method development framework
  • Drag and drop image processing
  • Advanced intensity based image registration
  • ROIs with thresholding, seeded region growing, and freehand definition
  • On-the-fly quantitative image mapping
  • Data browser with simple search functions for accessing stored protocols and recorded data
  • Database and archiving and report creation
  • An Acceleration Suite including Compressed Sensing, Simultaneous Multislice Imaging, Partial Fourier with homodyne reconstruction, and 3D GRAPPA with CAIPIRINHA
  • Wobble control on magnet front touchscreen display²
  • SLASER single voxel spectroscopy that is robust against B1 inhomogeneities and provides less chemical shift displacement
  • Magnet status display in ParaVision and remote instrument monitoring option

1Available for BioSpec 3T, Inline PET/MR, and PET/CT Si78
2For instruments with Animal Transport System

Highlights for MRI

  • Over 100 validated and ready-to-use in vivo protocols and scan programs for mice and rats with integrated examination guide for optimal scanning navigation and reproducibility
  • MRI CASL workflow package for optimal scanning and consistency
  • IntraGateUTE for virtually flow-artifact free cardiac scanning
  • Dynamic shimming capability1
  • B1 optimization and mapping
  • Fat-water separation imaging
  • Fat chemical shift corrected images
  • 3D GRAPPA and Compressed Sensing2
  • Fast online decisions and real-time calculations on all channels
  • MRI pulse program display

1 Work in progress research feature. Outcomes depend on the available shim hardware

2 Compressed Sensing is work in progress

Highlights for PET

  • Multimodal Scan Programs include complete instructions for interdependent PET/CT reconstruction steps
  • Extensive reconstruction algorithms (e.g. MLEM, OSEM, MAP, FBP)
  • MRI or CT based attenuation corrections with automatic loading of animal cradle and MRI coil and individual calculation of subject
  • Static, multi-stage, dynamic imaging
  • Wireless cardiac PET/MR imaging
  • Kinetic time course image reconstruction and segmentation
  • TAC display with Patlak fit for kinetic modeling
  • Advanced DOI
  • Scatter, randoms, isotope decay, and dead-time corrections
  • Custom isotope profiles

Highlights for µCT

  • Protocol library for mice and rats for anatomical reference
  • Static, multi-stage, dynamic imaging
  • 3D/2D
  • Step & shoot or continuous
  • Ultrafast low dose protocols
  • Cardiac & respiratory gating
  • Real-time adjustments preview
  • Smoothing, beam hardening & ring corrections
  • Hounsfield scaling


Videos covering everything from ParaVision basics to advanced topics to turtorials on lastest features can be found on (Login required)


Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging

Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory