Off-line Reaction Monitoring Using Advanced Chemical Profiling 2.0 Software

Monitoring chemical reactions is crucial for understanding, optimizing, and scaling up processes to ensure cost efficiency and high yields, while maintaining final product quality. By analyzing time-course data, kinetic information can be extracted to support predictive modeling, process optimization, and reaction risk management.

Advanced Chemical Profiling 2.0 software enables fully automated extraction of quantitative data from NMR spectra, including concentrations of starting materials, reactants, catalysts, by-products, and products. This application note shows how to set up a targeted quantification workflow for offline reaction monitoring, using the enzymatic hydrolysis of lactose in milk as an example.