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▶ Watch On-Demand | 57 Minutes

On-Demand Sessions: AI-Assisted Nanomechanical AFM Analysis in a Multi-Compartment Environment

Learn more  about biological sample analysis with AI-Assisted nanomechanical AFM techniques
Watch Now | 27 Minutes

Dissecting inegrin-mediated ECM-sensing using AFM-based single cell force spectroscopy (SCFS)

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Presented by Upnishad Sharma, Ph.D., Biophysics Laboratory, D-BSSE, ETH Zurich (May 21, 2025)

       PRESENTATION HIGHLIGHTS:

  • [00:01:14] Introduction: Mechanical cues in disease and homeostasis
  • [00:07:15] Research questions
  • [00:07:38] AFM-based single-cell force spectroscopy (SCFS)
  • [00:11:26] Investigating cell adhesion and bond behavior
  • [00:17:19] Summary
  • [00:20:49] Q&A

 

Watch Now | 26 Minutes

Live Demo

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Recorded on May 21, 2025

       PRESENTATION HIGHLIGHTS:

  • [00:00:00] Introduction & hardware set-up
  • [00:03:44] Software set-up
  • [00:04:32] Sample preparation
  • [00:11:07] Navigating the sample & data aquisition
  • [00:21:31] Q&A

 

Watch Now | 4 Minutes

Q&A

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       PRESENTATION HIGHLIGHTS:

  • [00:00:00] How can you handle the height differences of substrates for a large travel range during FM imaging of forced spectroscopy?
  • [00:01:20] What are the main challenges you faced during your experiments? 
  • [00:02:03] What is the exact probe you used?
  • [00:02:55] What types of cells can be recognized by AI in general?

 

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