Webinar Recap: Modelling 3d Tissue Flow Using Forces And Tissue Mechanics
In this webinar recap, Dr. Timo Betz from the University of Göttingen, talks about his use of light-sheet microscopy to investigate key questions about the mechanical forces and viscoelastic tissue properties underlying tissue flow.
Explore how researchers are using light-sheet microscopy to investigate tissue dynamics.
This webinar recap summarizes a presentation given by Dr. Timo Betz, a professor at the University of Göttingen, Germany, about his use of Bruker’s Luxendo MuVi SPIM light-sheet microscope to gain global insights into tissue dynamics.
He discussed the 3D mapping of tissue flow his lab conducted in order to create models for measuring and predicting tissue forces in future biophysical and biological experiments.
Audience Q&A and Other Answers
Download the webinar recap or watch the recording to learn more about these and other topics.
- How does the multi-view setup of the Luxendo MuVi SPIM enable 3D imaging of fast dynamics?
- How can insights into global tissue dynamics, such as those in spheroids and embryos, be obtained using light-sheet microscopy?
- How do mechanical forces and viscoelastic tissue properties contribute to tissue flow?
- What kind of experiments and models can be established to study tissue flow and forces in cancer spheroids and zebrafish embryos?
- How does altering the collagen concentration affect tissue invasion and cell migration in spheroids?
- How can pressure measurements and hydrogel deformation be used to study the effects of tissue swelling and bursting?
- How can the principles of biophysics be applied to study tissue migration during zebrafish development?
- What factors contribute to the stabilization of gastrulation, and can biophysics play a role in this process?
- What insights can be gained by combining advanced imaging, modeling, and biological experiments?