Biosensors for Molecular Interactions Bibliography
Introduction
Measuring real-time binding kinetics of molecular interactions is essential in both drug discovery and fundamental research. Quantifying association and dissociation rates, as well as overall binding stability, enables a detailed understanding of interaction mechanisms and provides critical insights into the functional behavior of therapeutic candidates. Kinetic analyses support the identification and optimization of lead molecules, help distinguish between binding modes, and allow researchers to characterize complex biomolecular systems with high precision.
This bibliography provides an overview of the literature for 4 different technologies for molecular interaction studies: scIC, switchSENSE®, SPR, and proFIRE®.
single-cell Interaction Cytometry (scIC) enables real-time binding kinetic measurements directly on living cells.
switchSENSE® offers in-depth characterization of complex interactions like ternary binding, avidity, aptamer folding or protein conformational changes.
Surface Plasmon Resonance (SPR) is a label-free high-throughput technology to study interactions.
proFIRE® can be used to purify and analyze DNA-protein conjugates.
switchSENSE®
| Title | Authors | Journal incl. edition | Year | Link |
|---|---|---|---|---|
| Restriction of Ku translocation protects telomere ends | Mattarocci, Stefano; Baconnais, Sonia; Roisné-Hamelin, Florian; Pobiega, Sabrina; Alibert, Olivier; Morin, Vincent; Deshayes, Alice; Veaute, Xavier; Ropars, Virginie; Chevreuil, Maelenn; Mehringer, Johannes; Busso, Didier; Mazon, Gerard; Fernandez Varela, Paloma; Le Cam, Éric; Charbonnier, Jean-Baptiste; Cuniasse, Philippe; Marcand, Stéphane | Nature Communications 16(1) | 2025 | https://doi.org/10.1038/s41467-025-61864-1 |
| Itaconate modulates immune responses via inhibition of peroxiredoxin 5 | Paulenda, Tomas; Echalar, Barbora; Potuckova, Lucie; Vachova, Veronika; Kleverov, Denis A.; Mehringer, Johannes; Potekhina, Ekaterina; Jacoby, Alex; Sen, Devashish; Nelson, Chris; Stegeman, Rick; Sukhov, Vladimir; Kemper, Danielle; Lichti, Cheryl F.; Day, Nicholas J.; Zhang, Tong; Husarcikova, Kamila; Bambouskova, Monika; Fremont, Daved H.; Qian, Wei-jun; Djuranovic, Sergej; Pavlovic-Djuranovic, Slavica; Belousov, Vsevolod V.; Krezel, Andrzej M.; Artyomov, Maxim N. | Nature Metabolism 7(6) | 2025 | https://doi.org/10.1038/s42255-025-01275-0 |
| Kinetic screening of nucleic acid ligand libraries for hit identification, binding mode characterization, and sequence optimization | De Pascali, Mareike C.; Dreymann, Nico; Menger, Marcus M.; Rant, Ulrich; Engelen, Wouter | Sensing and Bio-Sensing Research 49 | 2025 | https://doi.org/10.1016/j.sbsr.2025.100840 |
| FANCD2–FANCI surveys DNA and recognizes double- to single-stranded junctions | Alcón, Pablo; Kaczmarczyk, Artur P.; Ray, Korak Kumar; Liolios, Themistoklis; Guilbaud, Guillaume; Sijacki, Tamara; Shen, Yichao; McLaughlin, Stephen H.; Sale, Julian E.; Knipscheer, Puck; Rueda, David S.; Passmore, Lori A. | Nature 632(8027) | 2024 | https://doi.org/10.1038/s41586-024-07770-w |
| Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn | Reusch, Johannes; Andersen, Jan Terje; Rant, Ulrich; Schlothauer, Tilman | mAbs 16(1) | 2024 | https://doi.org/10.1080/19420862.2024.2361585 |
| Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1 | Harwardt, Julia; Geyer, Felix Klaus; Schoenfeld, Katrin; Baumstark, David; Molkenthin, Vera; Kolmar, Harald | Antibodies 13(2) | 2024 | https://doi.org/10.3390/antib13020036 |
| Reverse transcription as key step in RNA in vitro evolution with unnatural base pairs | Hoffmann, Eva S.; De Pascali, Mareike C.; Neu, Lukas; Domnick, Christof; Soldà, Alice; Kath-Schorr, Stephanie | RSC Chemical Biology 5(6) | 2024 | https://doi.org/10.1039/d4cb00084f |
| Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria | Dolcemascolo, Roswitha; Heras-Hernández, María; Goiriz, Lucas; Montagud-Martínez, Roser; Requena-Menéndez, Alejandro; Ruiz, Raúl; Pérez-Ràfols, Anna; Higuera-Rodríguez, R Anahí; Pérez-Ropero, Guillermo; Vranken, Wim F; Martelli, Tommaso; Kaiser, Wolfgang; Buijs, Jos; Rodrigo, Guillermo | eLife 12 | 2024 | https://doi.org/10.7554/elife.91777.3 |
| Kinetic FRET Assay to Measure Binding-Induced Conformational Changes of Nucleic Acids | Higuera-Rodriguez, R. Anahi; De Pascali, Mareike C.; Aziz, Masood; Sattler, Michael; Rant, Ulrich; Kaiser, Wolfgang | ACS Sensors 8(12) | 2023 | https://doi.org/10.1021/acssensors.3c01527 |
| Synthetic Antigen-Conjugated DNA Systems for Antibody Detection and Characterization | Ranallo, Simona; Bracaglia, Sara; Sorrentino, Daniela; Ricci, Francesco | ACS Sensors 8(7) | 2023 | https://doi.org/10.1021/acssensors.3c00564 |
| The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2 | Heerwig, Andreas; Kick, Alfred; Sommerfeld, Paul; Eimermacher, Sophia; Hartung, Frederick; Laube, Markus; Fischer, Dietmar; Pietzsch, Hans-Jürgen; Pietzsch, Jens; Löser, Reik; Mertig, Michael; Pietsch, Markus; Wodtke, Robert | International Journal of Molecular Sciences 24(2) | 2023 | https://doi.org/10.3390/ijms24021650 |
| Kinetic analysis of ternary and binary binding modes of the bispecific antibody emicizumab | Mak, Stefanie; Marszal, Agnes; Matscheko, Nena; Rant, Ulrich | mAbs 15(1) | 2023 | https://doi.org/10.1080/19420862.2022.2149053 |
| Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction | Kefala Stavridi, Antonia; Gontier, Amandine; Morin, Vincent; Frit, Philippe; Ropars, Virginie; Barboule, Nadia; Racca, Carine; Jonchhe, Sagun; Morten, Michael J; Andreani, Jessica; Rak, Alexey; Legrand, Pierre; Bourand-Plantefol, Alexa; Hardwick, Steven W; Chirgadze, Dimitri Y; Davey, Paul; De Oliveira, Taiana Maia; Rothenberg, Eli; Britton, Sebastien; Calsou, Patrick; Blundell, Tom L; Varela, Paloma F; Chaplin, Amanda K; Charbonnier, Jean-Baptiste | Nucleic Acids Research 51(21) | 2023 | https://doi.org/10.1093/nar/gkad863 |
| Plant polygalacturonase structures specify enzyme dynamics and processivities to fine-tune cell wall pectins | Safran, Josip; Tabi, Wafae; Ung, Vanessa; Lemaire, Adrien; Habrylo, Olivier; Bouckaert, Julie; Rouffle, Maxime; Voxeur, Aline; Pongrac, Paula; Bassard, Solène; Molinié, Roland; Fontaine, Jean-Xavier; Pilard, Serge; Pau-Roblot, Corinne; Bonnin, Estelle; Larsen, Danaé Sonja; Morel-Rouhier, Mélanie; Girardet, Jean-Michel; Lefebvre, Valérie; Sénéchal, Fabien; Mercadante, Davide; Pelloux, Jérôme | The Plant Cell 35(8) | 2023 | https://doi.org/10.1093/plcell/koad134 |
| Equine lactoferrin: Antioxidant properties related to divalent metal chelation | Narmuratova, Zhanar; Hentati, Faiez; Girardet, Jean-Michel; Narmuratova, Meyramkul; Cakir-Kiefer, Céline | LWT 161 | 2022 | https://doi.org/10.1016/j.lwt.2022.113426 |
| Structural basis for Cas9 off-target activity | Pacesa, Martin; Lin, Chun-Han; Cléry, Antoine; Saha, Aakash; Arantes, Pablo R.; Bargsten, Katja; Irby, Matthew J.; Allain, Frédéric H.-T.; Palermo, Giulia; Cameron, Peter; Donohoue, Paul D.; Jinek, Martin | Cell 185(22) | 2022 | https://doi.org/10.1016/j.cell.2022.09.026 |
| The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination | Sijacki, Tamara; Alcón, Pablo; Chen, Zhuo A.; McLaughlin, Stephen H.; Shakeel, Shabih; Rappsilber, Juri; Passmore, Lori A. | Nature Structural & Molecular Biology 29(9) | 2022 | https://doi.org/10.1038/s41594-022-00820-9 |
| Application of the SwitchSense Technique for the Study of Small Molecules’ (Ethidium Bromide and Selected Sulfonamide Derivatives) Affinity to DNA in Real Time | Ramotowska, Sandra; Spisz, Paulina; Brzeski, Jakub; Ciesielska, Aleksandra; Makowski, Mariusz | The Journal of Physical Chemistry B 126(38) | 2022 | https://doi.org/10.1021/acs.jpcb.2c03138 |
| Multivalent binding kinetics resolved by fluorescence proximity sensing | Schulte, Clemens; Soldà, Alice; Spänig, Sebastian; Adams, Nathan; Bekić, Ivana; Streicher, Werner; Heider, Dominik; Strasser, Ralf; Maric, Hans Michael | Communications Biology 5(1) | 2022 | https://doi.org/10.1038/s42003-022-03997-3 |
| Characterization of binding interactions of SARS-CoV-2 spike protein and DNA-peptide nanostructures | Kruse, Marlen; Altattan, Basma; Laux, Eva-Maria; Grasse, Nico; Heinig, Lars; Möser, Christin; Smith, David M.; Hölzel, Ralph | Scientific Reports 12(1) | 2022 | https://doi.org/10.1038/s41598-022-16914-9 |
| A Robust Assay to Monitor Ataxin-3 Amyloid Fibril Assembly | Figueiredo, Francisco; Lopes-Marques, Mónica; Almeida, Bruno; Matscheko, Nena; Martins, Pedro M.; Silva, Alexandra; Macedo-Ribeiro, Sandra | Cells 11(12) | 2022 | https://doi.org/10.3390/cells11121969 |
| Highly shape- and size-tunable membrane nanopores made with DNA | Xing, Yongzheng; Dorey, Adam; Jayasinghe, Lakmal; Howorka, Stefan | Nature Nanotechnology 17(7) | 2022 | https://doi.org/10.1038/s41565-022-01116-1 |
| The role of DNA nanostructures in the catalytic properties of an allosterically regulated protease | Kosinski, Richard; Perez, Joel Mieres; Schöneweiß, Elisa-C.; Ruiz-Blanco, Yasser B.; Ponzo, Irene; Bravo-Rodriguez, Kenny; Erkelenz, Michael; Schlücker, Sebastian; Uhlenbrock, Guido; Sanchez-Garcia, Elsa; Saccà, Barbara | Science Advances 8(1) | 2022 | https://doi.org/10.1126/sciadv.abk0425 |
| Measuring Influenza A Virus and Peptide Interaction Using Electrically Controllable DNA Nanolevers | Kruse, Marlen; Möser, Christin; Smith, David M.; Müller‐Landau, Hanna; Rant, Ulrich; Hölzel, Ralph; Bier, Frank F. | Advanced Materials Technologies 7(5) | 2022 | https://doi.org/10.1002/admt.202101141 |
| Impact of single mutations on binding kinetics of triplex forming oligos revealed by fluorescence proximity sensing in heliX® biosensor | Molkenthin, Vera; Baumstark, David; Schubert, Thomas; Längst, Gernot; Plach, Maximilian G. | BioRxiv | 2022 | https://doi.org/10.1101/2022.11.21.517309 |
| Application in nutrition: mineral binding | El Hajj, Sarah; Sepulveda-Rincon, Tatiana; Paris, Cédric; Giraud, Tristan; Csire, Gizella; Stefan, Loic; Selmeczi, Katalin; Girardet, Jean-Michel; Desobry, Stéphane; Bouhallab, Said; Muhr, Laurence; Gaucher, Caroline; Canabady-Rochelle, Laetitia | Biologically Active Peptides | 2021 | https://doi.org/10.1016/b978-0-12-821389-6.00016-9 |
| Tailored Biosensors for Drug Screening, Efficacy Assessment, and Toxicity Evaluation | Tao, Yi; Chen, Lin; Pan, Meiling; Zhu, Fei; Zhu, Dong | ACS Sensors 6(9) | 2021 | https://doi.org/10.1021/acssensors.1c01600 |
| Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion | Senoo, Akinobu; Ito, Sho; Nagatoishi, Satoru; Saito, Yutaro; Ueno, Go; Kuroda, Daisuke; Yoshida, Kouhei; Tashima, Takumi; Kudo, Shota; Sando, Shinsuke; Tsumoto, Kouhei | Communications Biology 4(1) | 2021 | https://doi.org/10.1038/s42003-021-02575-3 |
| Electrically Switchable Nanolever Technology for the Screening of Metal-Chelating Peptides in Hydrolysates | El Hajj, Sarah; Sepúlveda Rincón, Cindy Tatiana; Girardet, Jean-Michel; Cakir-Kiefer, Céline; Stefan, Loic; Zapata Montoya, José Edgar; Boschi-Muller, Sandrine; Gaucher, Caroline; Canabady-Rochelle, Laetitia | Journal of Agricultural and Food Chemistry 69(31) | 2021 | https://doi.org/10.1021/acs.jafc.1c02199 |
| Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action | Kast, Florian; Schwill, Martin; Stüber, Jakob C.; Pfundstein, Svende; Nagy-Davidescu, Gabriela; Rodríguez, Josep M. Monné; Seehusen, Frauke; Richter, Christian P.; Honegger, Annemarie; Hartmann, Karen Patricia; Weber, Thomas G.; Kroener, Felix; Ernst, Patrick; Piehler, Jacob; Plückthun, Andreas | Nature Communications 12(1) | 2021 | https://doi.org/10.1038/s41467-021-23948-6 |
| Macromolecular interactions in vitro, comparing classical and novel approaches | Velours, Christophe; Aumont-Nicaise, Magali; Uebel, Stephan; England, Patrick; Velazquez-Campoy, Adrian; Stroebel, David; Bec, Guillaume; Soule, Pierre; Quétard, Christophe; Ebel, Christine; Roussel, Alain; Charbonnier, Jean-Baptiste; Varela, Paloma Fernández | European Biophysics Journal 50(3-4) | 2021 | https://doi.org/10.1007/s00249-021-01517-5 |
| Biophysical Studies of the Binding of Viral RNA with the 80S Ribosome Using switchSENSE | Schenckbecher, Emma; Bec, Guillaume; Sakamoto, Taiichi; Meyer, Benoit; Ennifar, Eric | Methods in Molecular Biology | 2021 | https://doi.org/10.1007/978-1-0716-1197-5_15 |
| CMT2N-causing aminoacylation domain mutants enable Nrp1 interaction with AlaRS | Sun, Litao; Wei, Na; Kuhle, Bernhard; Blocquel, David; Novick, Scott; Matuszek, Zaneta; Zhou, Huihao; He, Weiwei; Zhang, Jingjing; Weber, Thomas; Horvath, Rita; Latour, Philippe; Pan, Tao; Schimmel, Paul; Griffin, Patrick R.; Yang, Xiang-Lei | Proceedings of the National Academy of Sciences 118(13) | 2021 | https://doi.org/10.1073/pnas.2012898118 |
| Standard operation procedure for switchSENSE DRX systems | Müller-Landau, Hanna; Varela, Paloma Fernández | European Biophysics Journal 50(3-4) | 2021 | https://doi.org/10.1007/s00249-021-01519-3 |
| switchSENSE Technology for Analysis of DNA Polymerase Kinetics | Bec, Guillaume; Ennifar, Eric | Methods in Molecular Biology | 2021 | https://doi.org/10.1007/978-1-0716-1126-5_8 |
| Oxidized glutathione promotes association between eukaryotic translation elongation factor 1Bγ and Ure2p glutathione transferase from Phanerochaete chrysosporium | Bchini, Raphael; Girardet, Jean‐Michel; Sormani, Rodnay; Gelhaye, Eric; Morel‐Rouhier, Mélanie | The FEBS Journal 288(9) | 2021 | https://doi.org/10.1111/febs.15614 |
| Molecular Dynamics to Elucidate the DNA-Binding Activity of AlpZ, a Member of the Gamma-Butyrolactone Receptor Family in Streptomyces ambofaciens | Vicente, Cláudia M.; Girardet, Jean-Michel; Hôtel, Laurence; Aigle, Bertrand | Frontiers in Microbiology 11 | 2020 | https://doi.org/10.3389/fmicb.2020.01255 |
| Affinity of chlordecone and chlordecol for human serum lipoproteins | Delannoy, Matthieu; Girardet, Jean-Michel; Djelti, Fathia; Yen, Frances T.; Cakir-Kiefer, Céline | Environmental Toxicology and Pharmacology 80 | 2020 | https://doi.org/10.1016/j.etap.2020.103486 |
| Sinorhizobium meliloti YrbA binds divalent metal cations using two conserved histidines | Roret, Thomas; Alloing, Geneviève; Girardet, Jean-Michel; Perrot, Thomas; Dhalleine, Tiphaine; Couturier, Jérémy; Frendo, Pierre; Didierjean, Claude; Rouhier, Nicolas | Bioscience Reports 40(10) | 2020 | https://doi.org/10.1042/bsr20202956 |
| Nucleotide binding kinetics and conformational change analysis of tissue transglutaminase with switchSENSE | Staffler, Regina; Pasternack, Ralf; Hils, Martin; Kaiser, Wolfgang; Möller, Friederike M. | Analytical Biochemistry 605 | 2020 | https://doi.org/10.1016/j.ab.2020.113719 |
| The trimer to monomer transition of Tumor Necrosis Factor-Alpha is a dynamic process that is significantly altered by therapeutic antibodies | Daub, Herwin; Traxler, Lukas; Ismajli, Fjolla; Groitl, Bastian; Itzen, Aymelt; Rant, Ulrich | Scientific Reports 10(1) | 2020 | https://doi.org/10.1038/s41598-020-66123-5 |
| Single-Molecule Sensing of DNA Intercalating Drugs in Water | Serres, Sandra; Tardin, Catherine; Salomé, Laurence | Analytical Chemistry 92(12) | 2020 | https://doi.org/10.1021/acs.analchem.0c00184 |
| An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2 | Kang, Hyun-Seo; Sánchez-Rico, Carolina; Ebersberger, Stefanie; Sutandy, F. X. Reymond; Busch, Anke; Welte, Thomas; Stehle, Ralf; Hipp, Clara; Schulz, Laura; Buchbender, Andreas; Zarnack, Kathi; König, Julian; Sattler, Michael | Proceedings of the National Academy of Sciences 117(13) | 2020 | https://doi.org/10.1073/pnas.1913483117 |
| Resolving Binding Events on the Multifunctional Human Serum Albumin | Wenskowsky, Lea; Wagner, Michael; Reusch, Johannes; Schreuder, Herman; Matter, Hans; Opatz, Till; Petry, Stefan Matthias | ChemMedChem 15(9) | 2020 | https://doi.org/10.1002/cmdc.202000069 |
| Preparation of single- and double-oligonucleotide antibody conjugates and their application for protein analytics | Wiener, Julius; Kokotek, Daniel; Rosowski, Simon; Lickert, Heiko; Meier, Matthias | Scientific Reports 10(1) | 2020 | https://doi.org/10.1038/s41598-020-58238-6 |
| Validation of the Slow Off‐Kinetics of Sirtuin‐Rearranging Ligands (SirReals) by Means of Label‐Free Electrically Switchable Nanolever Technology | Schiedel, Matthias; Daub, Herwin; Itzen, Aymelt; Jung, Manfred | ChemBioChem 21(8) | 2020 | https://doi.org/10.1002/cbic.201900527 |
| A Step-by-Step Guide to Study Protein–RNA Interactions | Cléry, Antoine; Gillioz, Laurent; Nguyen, Cristina K. X.; Allain, Frédéric H.-T. | CHIMIA 73(5) | 2019 | https://doi.org/10.2533/chimia.2019.406 |
| CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells | Blocquel, David; Sun, Litao; Matuszek, Zaneta; Li, Sheng; Weber, Thomas; Kuhle, Bernhard; Kooi, Grace; Wei, Na; Baets, Jonathan; Pan, Tao; Schimmel, Paul; Yang, Xiang-Lei | Proceedings of the National Academy of Sciences 116(39) | 2019 | https://doi.org/10.1073/pnas.1908288116 |
| A DNA-Based Biosensor Assay for the Kinetic Characterization of Ion-Dependent Aptamer Folding and Protein Binding | Ponzo, Irene; Möller, Friederike M.; Daub, Herwin; Matscheko, Nena | Molecules 24(16) | 2019 | https://doi.org/10.3390/molecules24162877 |
| Triazine-Modified 7-Deaza-2′-deoxyadenosines: Better Suited for Bioorthogonal Labeling of DNA by PCR than 2′-Deoxyuridines | Reisacher, Ulrike; Groitl, Bastian; Strasser, Ralf; Cserép, Gergely B.; Kele, Péter; Wagenknecht, Hans-Achim | Bioconjugate Chemistry 30(6) | 2019 | https://doi.org/10.1021/acs.bioconjchem.9b00295 |
| Specific inhibition of splicing factor activity by decoy RNA oligonucleotides | Denichenko, Polina; Mogilevsky, Maxim; Cléry, Antoine; Welte, Thomas; Biran, Jakob; Shimshon, Odelia; Barnabas, Georgina D.; Danan-Gotthold, Miri; Kumar, Saran; Yavin, Eylon; Levanon, Erez Y.; Allain, Frédéric H.; Geiger, Tamar; Levkowitz, Gil; Karni, Rotem | Nature Communications 10(1) | 2019 | https://doi.org/10.1038/s41467-019-09523-0 |
| Dissecting FOXP2 Oligomerization and DNA Binding | Häußermann, Katharina; Young, Gavin; Kukura, Philipp; Dietz, Hendrik | Angewandte Chemie International Edition 58(23) | 2019 | https://doi.org/10.1002/anie.201901734 |
| Tailored Peptide Phenyl Esters Block ClpXP Proteolysis by an Unusual Breakdown into a Heptamer–Hexamer Assembly | Lakemeyer, Markus; Bertosin, Eva; Möller, Friederike; Balogh, Dóra; Strasser, Ralf; Dietz, Hendrik; Sieber, Stephan A. | Angewandte Chemie International Edition 58(21) | 2019 | https://doi.org/10.1002/anie.201901056 |
| RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not | Webster, Michael W; Stowell, James AW; Passmore, Lori A | eLife 8 | 2019 | https://doi.org/10.7554/elife.40670 |
| Utilization of Staphylococcal Immune Evasion Protein Sbi as a Novel Vaccine Adjuvant | Yang, Yi; Back, Catherine R.; Gräwert, Melissa A.; Wahid, Ayla A.; Denton, Harriet; Kildani, Rebecca; Paulin, Joshua; Wörner, Kristin; Kaiser, Wolgang; Svergun, Dmitri I.; Sartbaeva, Asel; Watts, Andrew G.; Marchbank, Kevin J.; van den Elsen, Jean M. H. | Frontiers in Immunology 9 | 2019 | https://doi.org/10.3389/fimmu.2018.03139 |
| Magnesium-Dependent Electrical Actuation and Stability of DNA Origami Rods | Kroener, Felix; Traxler, Lukas; Heerwig, Andreas; Rant, Ulrich; Mertig, Michael | ACS Applied Materials & Interfaces 11(2) | 2019 | https://doi.org/10.1021/acsami.8b18611 |
| Structural and Kinetic Profiling of Allosteric Modulation of Duplex DNA Induced by DNA‐Binding Polyamide Analogues | Aman, Khalid; Padroni, Giacomo; Parkinson, John A.; Welte, Thomas; Burley, Glenn A. | Chemistry – A European Journal 25(11) | 2019 | https://doi.org/10.1002/chem.201805338 |
| Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus | Kyriakou, Eleni; Schmidt, Stefanie; Dodd, Garron T.; Pfuhlmann, Katrin; Simonds, Stephanie E.; Lenhart, Dominik; Geerlof, Arie; Schriever, Sonja C.; De Angelis, Meri; Schramm, Karl-Werner; Plettenburg, Oliver; Cowley, Michael A.; Tiganis, Tony; Tschöp, Matthias H.; Pfluger, Paul T.; Sattler, Michael; Messias, Ana C. | Journal of Medicinal Chemistry 61(24) | 2018 | https://doi.org/10.1021/acs.jmedchem.8b01224 |
| Assembly and Characterization of a Slingshot DNA Nanostructure for the Analysis of Bivalent and Bispecific Analytes with Biosensors | Hampel, Paul A.; Strasser, Ralf; Fischer, Frank; Rant, Ulrich | Langmuir 34(49) | 2018 | https://doi.org/10.1021/acs.langmuir.8b02124 |
| XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining | Nemoz, Clement; Ropars, Virginie; Frit, Philippe; Gontier, Amandine; Drevet, Pascal; Yu, Jinchao; Guerois, Raphaël; Pitois, Aurelien; Comte, Audrey; Delteil, Christine; Barboule, Nadia; Legrand, Pierre; Baconnais, Sonia; Yin, Yandong; Tadi, Satish; Barbet-Massin, Emeline; Berger, Imre; Le Cam, Eric; Modesti, Mauro; Rothenberg, Eli; Calsou, Patrick; Charbonnier, Jean Baptiste | Nature Structural & Molecular Biology 25(10) | 2018 | https://doi.org/10.1038/s41594-018-0133-6 |
| Fungal Glutathione Transferases as Tools to Explore the Chemical Diversity of Amazonian Wood Extractives | Perrot, Thomas; Schwartz, Mathieu; Saiag, Fanny; Salzet, Guillaume; Dumarçay, Stéphane; Favier, Frédérique; Gérardin, Philippe; Girardet, Jean-Michel; Sormani, Rodnay; Morel-Rouhier, Mélanie; Amusant, Nadine; Didierjean, Claude; Gelhaye, Eric | ACS Sustainable Chemistry & Engineering 6(10) | 2018 | https://doi.org/10.1021/acssuschemeng.8b02636 |
| DNA Primer Extension with Cyclopropenylated 7‐Deaza‐2′‐deoxyadenosine and Efficient Bioorthogonal Labeling in Vitro and in Living Cells | Ploschik, Damian; Rönicke, Franziska; Beike, Hanna; Strasser, Ralf; Wagenknecht, Hans‐Achim | ChemBioChem 19(18) | 2018 | https://doi.org/10.1002/cbic.201800354 |
| mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases | Webster, Michael W.; Chen, Ying-Hsin; Stowell, James A.W.; Alhusaini, Najwa; Sweet, Thomas; Graveley, Brenton R.; Coller, Jeff; Passmore, Lori A. | Molecular Cell 70(6) | 2018 | https://doi.org/10.1016/j.molcel.2018.05.033 |
| ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase | Vo, My-Nuong; Terrey, Markus; Lee, Jeong Woong; Roy, Bappaditya; Moresco, James J.; Sun, Litao; Fu, Hongjun; Liu, Qi; Weber, Thomas G.; Yates, John R.; Fredrick, Kurt; Schimmel, Paul; Ackerman, Susan L. | Nature 557(7706) | 2018 | https://doi.org/10.1038/s41586-018-0137-8 |
| A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding | Stowell, James A.W.; Wagstaff, Jane L.; Hill, Chris H.; Yu, Minmin; McLaughlin, Stephen H.; Freund, Stefan M.V.; Passmore, Lori A. | Journal of Biological Chemistry 293(24) | 2018 | https://doi.org/10.1074/jbc.ra118.002291 |
| Preclinical Development of a Novel, Orally-Administered Anti-Tumour Necrosis Factor Domain Antibody for the Treatment of Inflammatory Bowel Disease | Crowe, J. Scott; Roberts, Kevin J.; Carlton, Timothy M.; Maggiore, Luana; Cubitt, Marion F.; Clare, Simon; Harcourt, Katherine; Reckless, Jill; MacDonald, Thomas T.; Ray, Keith P.; Vossenkämper, Anna; West, Michael R. | Scientific Reports 8(1) | 2018 | https://doi.org/10.1038/s41598-018-23277-7 |
| Mapping the sugar dependency for rational generation of a DNA-RNA hybrid-guided Cas9 endonuclease | Rueda, Fernando Orden; Bista, Michal; Newton, Matthew D.; Goeppert, Anne U.; Cuomo, M. Emanuela; Gordon, Euan; Kröner, Felix; Read, Jon A.; Wrigley, Jonathan D.; Rueda, David; Taylor, Benjamin J. M. | Nature Communications 8(1) | 2017 | https://doi.org/10.1038/s41467-017-01732-9 |
| Electrical Actuation of a DNA Origami Nanolever on an Electrode | Kroener, Felix; Heerwig, Andreas; Kaiser, Wolfgang; Mertig, Michael; Rant, Ulrich | Journal of the American Chemical Society 139(46) | 2017 | https://doi.org/10.1021/jacs.7b10862 |
| Physical interaction between the strawberry allergen Fra a 1 and an associated partner FaAP: Interaction of Fra a 1 proteins and FaAP | Franz-Oberdorf, Katrin; Langer, Andreas; Strasser, Ralf; Isono, Erika; Ranftl, Quirin L.; Wunschel, Christian; Schwab, Wilfried | Proteins: Structure, Function, and Bioinformatics 85(10) | 2017 | https://doi.org/10.1002/prot.25343 |
| Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy | Blocquel, David; Li, Sheng; Wei, Na; Daub, Herwin; Sajish, Mathew; Erfurth, Maria-Luise; Kooi, Grace; Zhou, Jiadong; Bai, Ge; Schimmel, Paul; Jordanova, Albena; Yang, Xiang-Lei | Nucleic Acids Research 45(13) | 2017 | https://doi.org/10.1093/nar/gkx455 |
| Structural study of the Fox-1 RRM protein hydration reveals a role for key water molecules in RRM-RNA recognition | Krepl, Miroslav; Blatter, Markus; Cléry, Antoine; Damberger, Fred F.; Allain, Frédéric H.T.; Sponer, Jiri | Nucleic Acids Research 45(13) | 2017 | https://doi.org/10.1093/nar/gkx418 |
| switchSENSE: A new technology to study protein-RNA interactions | Cléry, Antoine; Sohier, Thibault J.M.; Welte, Thomas; Langer, Andreas; Allain, Frédéric H.T. | Methods 118-119 | 2017 | https://doi.org/10.1016/j.ymeth.2017.03.004 |
| Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon | Vandervelde, Alexandra; Drobnak, Igor; Hadži, San; Sterckx, Yann G.-J.; Welte, Thomas; De Greve, Henri; Charlier, Daniel; Efremov, Rouslan; Loris, Remy; Lah, Jurij | Nucleic Acids Research 45(6) | 2017 | https://doi.org/10.1093/nar/gkx108 |
| The long zinc finger domain of PRDM9 forms a highly stable and long-lived complex with its DNA recognition sequence | Striedner, Yasmin; Schwarz, Theresa; Welte, Thomas; Futschik, Andreas; Rant, Ulrich; Tiemann-Boege, Irene | Chromosome Research 25(2) | 2017 | https://doi.org/10.1007/s10577-017-9552-1 |
| Specialized interfaces of Smc5/6 control hinge stability and DNA association | Alt, Aaron; Dang, Hung Q.; Wells, Owen S.; Polo, Luis M.; Smith, Matt A.; McGregor, Grant A.; Welte, Thomas; Lehmann, Alan R.; Pearl, Laurence H.; Murray, Johanne M.; Oliver, Antony W. | Nature Communications 8(1) | 2017 | https://doi.org/10.1038/ncomms14011 |
| Polymerase/DNA interactions and enzymatic activity: multi-parameter analysis with electro-switchable biosurfaces | Langer, Andreas; Schräml, Michael; Strasser, Ralf; Daub, Herwin; Myers, Thomas; Heindl, Dieter; Rant, Ulrich | Scientific Reports 5(1) | 2015 | https://doi.org/10.1038/srep12066 |
| Detection of the Carcinogenic Water Pollutant Benzo[a]pyrene with an Electro-Switchable Biosurface | Lux, Gregor; Langer, Andreas; Pschenitza, Michael; Karsunke, Xaver; Strasser, Ralf; Niessner, Reinhard; Knopp, Dietmar; Rant, Ulrich | Analytical Chemistry 87(8) | 2015 | https://doi.org/10.1021/acs.analchem.5b00648 |
| Molecular Dynamics of DNA–Protein Conjugates on Electrified Surfaces: Solutions to the Drift-Diffusion Equation | Langer, A.; Kaiser, W.; Svejda, M.; Schwertler, P.; Rant, U. | The Journal of Physical Chemistry B 118(2) | 2014 | https://doi.org/10.1021/jp410640z |
| Protein analysis by time-resolved measurements with an electro-switchable DNA chip | Langer, Andreas; Hampel, Paul A.; Kaiser, Wolfgang; Knezevic, Jelena; Welte, Thomas; Villa, Valentina; Maruyama, Makiko; Svejda, Matej; Jähner, Simone; Fischer, Frank; Strasser, Ralf; Rant, Ulrich | Nature Communications 4(1) | 2013 | https://doi.org/10.1038/ncomms3099 |
| Covalent attachment of functionalized cardiolipin on a biosensor gold surface allows repetitive measurements of anticardiolipin antibodies in serum | Schlichtiger, Alice; Baier, Claudia; Yin, Meng-Xin; Holmes, Andrew B.; Maruyama, Makiko; Strasser, Ralf; Rant, Ulrich; Thaler, Markus; Luppa, Peter B. | Analytical and Bioanalytical Chemistry 405(1) | 2013 | https://doi.org/10.1007/s00216-012-6467-8 |
| Sensing with electro-switchable biosurfaces | Rant, Ulrich | Bioanalytical Reviews 4(2-4) | 2012 | https://doi.org/10.1007/s12566-012-0030-0 |
| Messung molekularer Interaktion mit dynamischen Oberflächensensoren | Strasser, Ralf; Scholl, Dirk; Hampel, Paul; Langer, Andreas; Rant, Ulrich | BIOspektrum 18(7) | 2012 | https://doi.org/10.1007/s12268-012-0252-2 |
| Quantitation of Affinity, Avidity, and Binding Kinetics of Protein Analytes with a Dynamically Switchable Biosurface | Knezevic, Jelena; Langer, Andreas; Hampel, Paul A.; Kaiser, Wolfgang; Strasser, Ralf; Rant, Ulrich | Journal of the American Chemical Society 134(37) | 2012 | https://doi.org/10.1021/ja3061276 |
| Leichte Proteine schwingen besser | Strasser, Ralf; Niemax, Jens; Hampel, Paul; Rant, Ulrich | Nachrichten aus der Chemie 58(10) | 2010 | https://doi.org/10.1002/nadc.201073904 |
| Conformations of End-Tethered DNA Molecules on Gold Surfaces: Influences of Applied Electric Potential, Electrolyte Screening, and Temperature | Kaiser, Wolfgang; Rant, Ulrich | Journal of the American Chemical Society 132(23) | 2010 | https://doi.org/10.1021/ja908727d |
| Platform for in situ real-time measurement of protein-induced conformational changes of DNA | Spuhler, Philipp S.; Knežević, Jelena; Yalçin, Ayça; Bao, Qiuye; Pringsheim, Erika; Dröge, Peter; Rant, Ulrich; Ünlü, M. Selim | Proceedings of the National Academy of Sciences 107(4) | 2010 | https://doi.org/10.1073/pnas.0912182107 |
| Electrical Manipulation of DNA on Metal Surfaces | Tornow, Marc; Arinaga, Kenji; Rant, Ulrich | NanoBioTechnology | 2008 | https://doi.org/10.1007/978-1-59745-218-2_9 |
| Switchable DNA interfaces for the highly sensitive detection of label-free DNA targets | Rant, Ulrich; Arinaga, Kenji; Scherer, Simon; Pringsheim, Erika; Fujita, Shozo; Yokoyama, Naoki; Tornow, Marc; Abstreiter, Gerhard | Proceedings of the National Academy of Sciences 104(44) | 2007 | https://doi.org/10.1073/pnas.0703974104 |
| Controlling the surface density of DNA on gold by electrically induced desorption | Arinaga, Kenji; Rant, Ulrich; Knežević, Jelena; Pringsheim, Erika; Tornow, Marc; Fujita, Shozo; Abstreiter, Gerhard; Yokoyama, Naoki | Biosensors and Bioelectronics 23(3) | 2007 | https://doi.org/10.1016/j.bios.2007.04.012 |
| Dynamics of end grafted DNA molecules and possible biosensor applications | Sendner, C.; Kim, Yong W.; Rant, U.; Arinaga, K.; Tornow, M.; Netz, R. R. | physica status solidi (a) 203(14) | 2006 | https://doi.org/10.1002/pssa.200622444 |
| Electrical manipulation of oligonucleotides grafted to charged surfaces | Rant, Ulrich; Arinaga, Kenji; Fujita, Shozo; Yokoyama, Naoki; Abstreiter, Gerhard; Tornow, Marc | Organic & Biomolecular Chemistry 4(18) | 2006 | https://doi.org/10.1039/b605712h |
| The Role of Surface Charging during the Coadsorption of Mercaptohexanol to DNA Layers on Gold: Direct Observation of Desorption and Layer Reorientation | Arinaga, K.; Rant, U.; Tornow, M.; Fujita, S.; Abstreiter, G.; Yokoyama, N. | Langmuir 22(13) | 2006 | https://doi.org/10.1021/la060324m |
| Dissimilar Kinetic Behavior of Electrically Manipulated Single- and Double-Stranded DNA Tethered to a Gold Surface | Rant, Ulrich; Arinaga, Kenji; Tornow, Marc; Kim, Yong Woon; Netz, Roland R.; Fujita, Shozo; Yokoyama, Naoki; Abstreiter, Gerhard | Biophysical Journal 90(10) | 2006 | https://doi.org/10.1529/biophysj.105.078857 |
| Dynamic Electrical Switching of DNA Layers on a Metal Surface | Rant, Ulrich; Arinaga, Kenji; Fujita, Shozo; Yokoyama, Naoki; Abstreiter, Gerhard; Tornow, Marc | Nano Letters 4(12) | 2004 | https://doi.org/10.1021/nl0484494 |
| Structural Properties of Oligonucleotide Monolayers on Gold Surfaces Probed by Fluorescence Investigations | Rant, Ulrich; Arinaga, Kenji; Fujita, Shozo; Yokoyama, Naoki; Abstreiter, Gerhard; Tornow, Marc | Langmuir 20(23) | 2004 | https://doi.org/10.1021/la0492963 |
| Excessive Counterion Condensation on Immobilized ssDNA in Solutions of High Ionic Strength | Rant, Ulrich; Arinaga, Kenji; Fujiwara, Tsuyoshi; Fujita, Shozo; Tornow, Marc; Yokoyama, Naoki; Abstreiter, Gerhard | Biophysical Journal 85(6) | 2003 | https://doi.org/10.1016/s0006-3495(03)74800-0 |
proFIRE®
| Title | Authors | Journal incl. edition | Year | Link |
|---|---|---|---|---|
| A modular DNA origami nanocompartment for engineering a cell-free, protein unfolding and degradation pathway | Huang, J.; Jaekel, A.; van den Boom, J.; Podlesainski, D.; Elnaggar, M.; Heuer-Jungemann, A.; Kaiser, M.; Meyer, H.; Saccà, B. | Nature Nanotechnology 19(10) | 2024 | https://doi.org/10.1038/s41565-024-01738-7 |
| DNA origami traps for large viruses | Monferrer, Alba; Kohler, Fabian; Sigl, Christian; Schachtner, Michael; Peterhoff, David; Asbach, Benedikt; Wagner, Ralf; Dietz, Hendrik | Cell Reports Physical Science 4(1) | 2023 | https://doi.org/10.1016/j.xcrp.2022.101237 |
| Programmable multispecific DNA-origami-based T-cell engagers | Wagenbauer, Klaus F.; Pham, Nhi; Gottschlich, Adrian; Kick, Benjamin; Kozina, Viktorija; Frank, Christopher; Trninic, Daniela; Stömmer, Pierre; Grünmeier, Ruth; Carlini, Emanuele; Tsiverioti, Christina Angeliki; Kobold, Sebastian; Funke, Jonas J.; Dietz, Hendrik | Nature Nanotechnology 18(11) | 2023 | https://doi.org/10.1038/s41565-023-01471-7 |
| Sensitive Protein Detection Using Site-Specifically Oligonucleotide-Conjugated Nanobodies | Al-Amin, Rasel A.; Muthelo, Phathutshedzo M.; Abdurakhmanov, Eldar; Vincke, Cécile; Amin, Shahnaz P.; Muyldermans, Serge; Danielson, U. Helena; Landegren, Ulf | Analytical Chemistry 94(28) | 2022 | https://doi.org/10.1021/acs.analchem.2c00584 |
| DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease | Reinking, Hannah K.; Kang, Hyun-Seo; Götz, Maximilian J.; Li, Hao-Yi; Kieser, Anja; Zhao, Shubo; Acampora, Aleida C.; Weickert, Pedro; Fessler, Evelyn; Jae, Lucas T.; Sattler, Michael; Stingele, Julian | Molecular Cell 80(1) | 2020 | https://doi.org/10.1016/j.molcel.2020.08.003 |
| A compact nanobody-DNAzyme conjugate enables antigen detection and signal amplification | Bernardinelli, Giulio; Oloketuyi, Sandra; Werner, Salesia Franziska; Mazzega, Elisa; Högberg, Björn; de Marco, Ario | New Biotechnology 56 | 2020 | https://doi.org/10.1016/j.nbt.2019.10.009 |
single-cell Interaction Cytometry(scIC)
| Title | Authors | Journal incl. edition | Year | Link |
|---|---|---|---|---|
| SPARK-seq: A high-throughput platform for aptamer discovery and kinetic profiling | Luo, Guoyan; Song, Jia; Fu, Yongbo; Jiang, Yuanjie; Gao, Yuan; Zhong, Zhixing; Li, Ling; Wei, Yong; Jia, Hao-Ran; Guo, Lu; Fu, Ting; Wu, Qin; Tan, Weihong | Science 391(6780) | 2026 | https://doi.org/10.1126/science.adv6127 |
| PET-based tracking of CAR T cells and viral gene transfer using a cell surface reporter that binds to lanthanide complexes | Morath, Volker; Fritschle, Katja; Warmuth, Linda; Anneser, Markus; Dötsch, Sarah; Živanić, Milica; Krumwiede, Luisa; Bösl, Philipp; Bozoglu, Tarik; Robu, Stephanie; Libertini, Silvana; Kossatz, Susanne; Kupatt, Christian; Schwaiger, Markus; Steiger, Katja; Busch, Dirk H.; Skerra, Arne; Weber, Wolfgang A. | Nature Biomedical Engineering 9(11) | 2025 | https://doi.org/10.1038/s41551-025-01415-7 |
| Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1 | Harwardt, Julia; Geyer, Felix Klaus; Schoenfeld, Katrin; Baumstark, David; Molkenthin, Vera; Kolmar, Harald | Antibodies 13(2) | 2024 | https://doi.org/10.3390/antib13020036 |
Surface Plasmon Resonance
| Title | Authors | Journal incl. edition | Year | Link |
|---|---|---|---|---|
| Primate-conserved carbonic anhydrase IV and murine-restricted LY6C1 enable blood-brain barrier crossing by engineered viral vectors | Shay, Timothy F.; Sullivan, Erin E.; Ding, Xiaozhe; Chen, Xinhong; Ravindra Kumar, Sripriya; Goertsen, David; Brown, David; Crosby, Anaya; Vielmetter, Jost; Borsos, Máté; Wolfe, Damien A.; Lam, Annie W.; Gradinaru, Viviana | Science Advances 9(16) | 2023 | https://doi.org/10.1126/sciadv.adg6618 |
| Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes | Fan, Chengcheng; Cohen, Alexander A.; Park, Miso; Hung, Alfur Fu-Hsin; Keeffe, Jennifer R.; Gnanapragasam, Priyanthi N.P.; Lee, Yu E.; Gao, Han; Kakutani, Leesa M.; Wu, Ziyan; Kleanthous, Harry; Malecek, Kathryn E.; Williams, John C.; Bjorkman, Pamela J. | Immunity 55(12) | 2022 | https://doi.org/10.1016/j.immuni.2022.10.019 |
| Structural insights into the interaction of botulinum neurotoxin a with its neuronal receptor SV2C | Li, Xiaodan; Brunner, Cyrill; Wu, Yufan; Leka, Oneda; Schneider, Gisbert; Kammerer, Richard A. | Toxicon 175 | 2020 | https://doi.org/10.1016/j.toxicon.2019.11.010 |
| Interaction analysis of glycoengineered antibodies with CD16a: a native mass spectrometry approach | Hajduk, Joanna; Brunner, Cyrill; Malik, Sebastian; Bangerter, Jana; Schneider, Gisbert; Thomann, Marco; Reusch, Dietmar; Zenobi, Renato | mAbs 12(1) | 2020 | https://doi.org/10.1080/19420862.2020.1736975 |
| A comprehensive search of functional sequence space using large mammalian display libraries created by gene editing | Parthiban, Kothai; Perera, Rajika L.; Sattar, Maheen; Huang, Yanchao; Mayle, Sophie; Masters, Edward; Griffiths, Daniel; Surade, Sachin; Leah, Rachael; Dyson, Michael R.; McCafferty, John | mAbs 11(5) | 2019 | https://doi.org/10.1080/19420862.2019.1618673 |
| A Rationally Designed Humanized Antibody Selective for Amyloid Beta Oligomers in Alzheimer’s Disease | Gibbs, Ebrima; Silverman, Judith M.; Zhao, Beibei; Peng, Xubiao; Wang, Jing; Wellington, Cheryl L.; Mackenzie, Ian R.; Plotkin, Steven S.; Kaplan, Johanne M.; Cashman, Neil R. | Scientific Reports 9(1) | 2019 | https://doi.org/10.1038/s41598-019-46306-5 |
| Surveying GPCR solubilisation conditions using surface plasmon resonance | Navratilova, Iva Hopkins; Aristotelous, Tonia; Bird, Louise E.; Hopkins, Andrew L. | Analytical Biochemistry 556 | 2018 | https://doi.org/10.1016/j.ab.2018.06.012 |
| Direct loading of CTL epitopes onto MHC class I complexes on dendritic cell surface in vivo | Wang, Peng; Dong, Shuyun; Zhao, Peng; He, Xiao; Chen, Mingnan | Biomaterials 182 | 2018 | https://doi.org/10.1016/j.biomaterials.2018.08.008 |
| An Albumin-binding Polypeptide Both Targets Cytotoxic T Lymphocyte Vaccines to Lymph Nodes and Boosts Vaccine Presentation by Dendritic Cells | Wang, Peng; Zhao, Peng; Dong, Shuyun; Xu, Tiefeng; He, Xiao; Chen, Mingnan | Theranostics 8(1) | 2018 | https://doi.org/10.7150/thno.21691 |
| Towards Improved Oligonucleotide Therapeutics Through Faster Target Binding Kinetics | Menzi, Mirjam; Wild, Bettina; Pradère, Ugo; Malinowska, Anna L.; Brunschweiger, Andreas; Lightfoot, Helen L.; Hall, Jonathan | Chemistry – A European Journal 23(57) | 2017 | https://doi.org/10.1002/chem.201701670 |
| Characterization of Labeled Reagents in Ligand-Binding Assays by A Surface Plasmon Resonance Biosensor | Duo, Jia; Bruno, JoAnne; Piccoli, Steven; DeSilva, Binodh; Zhang, Yan J | Bioanalysis 9(2) | 2017 | https://doi.org/10.4155/bio-2016-0204 |
| Biophysical characterization of E. coli TolC interaction with the known blocker hexaamminecobalt | Gilardi, A.; Bhamidimarri, S.P.; Brönstrup, M.; Bilitewski, U.; Marreddy, R.K.R.; Pos, K.M.; Benier, L.; Gribbon, P.; Winterhalter, M.; Windshügel, B. | Biochimica et Biophysica Acta (BBA) - General Subjects 1861(11) | 2017 | https://doi.org/10.1016/j.bbagen.2017.07.014 |
| A mutant O-GlcNAcase enriches Drosophila developmental regulators | Selvan, Nithya; Williamson, Ritchie; Mariappa, Daniel; Campbell, David G; Gourlay, Robert; Ferenbach, Andrew T; Aristotelous, Tonia; Hopkins-Navratilova, Iva; Trost, Matthias; van Aalten, Daan M F | Nature Chemical Biology 13(8) | 2017 | https://doi.org/10.1038/nchembio.2404 |
| Novel multispecific heterodimeric antibody format allowing modular assembly of variable domain fragments | Egan, Timothy J.; Diem, Dania; Weldon, Richard; Neumann, Tessa; Meyer, Sebastian; Urech, David M. | mAbs 9(1) | 2017 | https://doi.org/10.1080/19420862.2016.1248012 |
| ANGPTL8 Blockade With a Monoclonal Antibody Promotes Triglyceride Clearance, Energy Expenditure, and Weight Loss in Mice | Gusarova, Viktoria; Banfi, Serena; Alexa-Braun, Corey A.; Shihanian, Lisa M.; Mintah, Ivory J.; Lee, Joseph S.; Xin, Yurong; Su, Qi; Kamat, Vishal; Cohen, Jonathan C.; Hobbs, Helen H.; Zambrowicz, Brian; Yancopoulos, George D.; Murphy, Andrew J.; Gromada, Jesper | Endocrinology 158(5) | 2017 | https://doi.org/10.1210/en.2016-1894 |
| Exploring sensitivity & throughput of a parallel flow SPRi biosensor for characterization of antibody-antigen interaction | Kamat, Vishal; Rafique, Ashique | Analytical Biochemistry 525 | 2017 | https://doi.org/10.1016/j.ab.2017.02.007 |
| Designing binding kinetic assay on the bio-layer interferometry (BLI) biosensor to characterize antibody-antigen interactions | Kamat, Vishal; Rafique, Ashique | Analytical Biochemistry 536 | 2017 | https://doi.org/10.1016/j.ab.2017.08.002 |
| Generation and analyses of human synthetic antibody libraries and their application for protein microarrays | Säll, Anna; Walle, Maria; Wingren, Christer; Müller, Susanne; Nyman, Tomas; Vala, Andrea; Ohlin, Mats; Borrebaeck, Carl A. K.; Persson, Helena | Protein Engineering Design and Selection 29(10) | 2016 | https://doi.org/10.1093/protein/gzw042 |
| De Novo Fragment Design for Drug Discovery and Chemical Biology | Rodrigues, Tiago; Reker, Daniel; Welin, Martin; Caldera, Michael; Brunner, Cyrill; Gabernet, Gisela; Schneider, Petra; Walse, Björn; Schneider, Gisbert | Angewandte Chemie International Edition 54(50) | 2015 | https://doi.org/10.1002/anie.201508055 |
| A mutant O-GlcNAcase as a probe to reveal global dynamics of protein O-GlcNAcylation during <i>Drosophila</i> embryonic development | Mariappa, Daniel; Selvan, Nithya; Borodkin, Vladimir S.; Alonso, Jana; Ferenbach, Andrew T.; Shepherd, Claire; Navratilova, Iva Hopkins; van Aalten, Daan M.F. | Biochemical Journal 470(2) | 2015 | https://doi.org/10.1042/bj20150610 |
| Fragment screening by SPR and advanced application to GPCRs | Shepherd, Claire A.; Hopkins, Andrew L.; Navratilova, Iva | Progress in Biophysics and Molecular Biology 116(2-3) | 2014 | https://doi.org/10.1016/j.pbiomolbio.2014.09.008 |