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Exploring Neural Circuits with Quartet: An Innovative Multi-Region Miniscope for Capturing Diverse Calcium Dynamics During Free Behavior

Learn about the innovative capabilities of the Quartet multi-region miniscope 

Powerful solutions for neuroscientists with the Quartet multi-region miniscope 

During this webinar, Dr. Roshni Christo and Dr. Tina Mahmoudi from Bruker discuss how the Quartet System is a multi-region miniscope uniquely equipped to unravel the brain’s complex and interconnected circuitry with simultaneous imaging of multiple brain regions in freely behaving animals. Viewers can also expect to learn about Quartet’s software capabilities and see first-hand how to analyze data from a variety of experimental setups.

 

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Presenters’ Abstract

The brain’s complex, interconnected circuitry necessitates simultaneous imaging in multiple brain regions of animals exhibiting naturalistic behavior. The Quartet, as previously presented, is the only patented technology for simultaneous, multi-region imaging allowing for the longitudinal assessment of both interregional and intraregional neuronal populations in freely behaving animals.

The Quartet system stands as a powerful hardware and software solution for neuroscientists. Engineered with strategic precision to keep optics away from the animal's head, the Quartet boasts a minimal footprint, enabling simultaneous imaging of up to four regions in a rodent brain. This design facilitates a wide range of experiments, including swimming paradigms. Furthermore, the system’s specially developed software facilitates live recording and real-time analysis across multiple regions, enabling longitudinal imaging and tracking 100s of individual neurons over time for a comprehensive understanding of brain function.

This webinar offers an overview of the software’s recording capabilities and its data extraction and analysis workflow. We also present analyzed data samples in cortical and deep brain regions in multiple experimental set-ups, including open-field and swimming tests.

Find out more about the technology featured in this webinar or our other solutions for capturing diverse calcium dynamics during free behavior:

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Speaker

Roshni Christo, Ph.D., Senior Application Scientist, Bruker

Dr. Christo a Bruker Field Application Scientist, has 10+ years of neuroscience research experience. She completed her postdoctoral research at Baylor College of Medicine, Texas. Dr. Christo was instrumental in designing fluorescent constructs to tag dendritic spines undergoing plasticity and her research focused on neurodegenerative diseases using molecular techniques and in vivo imaging.

Tina Mahmoudi, Ph.D., Software Engineer, Bruker

Dr. Tina Mahmoudi is a Software Engineer at Bruker with 5+ years of research experience. She completed her undergraduate in Electrical Engineering from McMaster University and her Masters in Biomedical Engineering from the University of Toronto. Her research focus lies in analytical software development, signal processing, and biomedical instrumentation. 

Past Webinars