Poster Hall Pharma/Biopharma

Poster Hall Pharma/Biopharma

Research topics and advances in Pharma/BioPharma

The ever increasing need to accelerate time to market for new drugs places a burden on analytical labs in terms of sample volume and confidence in data required for decision making. Innovations in trapped ion mobility mass spectrometry and software give BioPharma scientists new tools to characterize biologic drugs with more speed and keep up with the pace of development. Mass spectrometry imaging is becoming an essential tool to understand diseases and determine drugs PK and metabolism which are essential to address the right tissue and evaluate toxicity early. 

ASMS 2020

ASMS 2020

Poster 2020: Identification and differentiation of disulfide bonded isomers of the µ-conotoxin PIIIA by trapped ion mobility spectrometry 

Poster 2020: Integrated characterization and screening workflows to simplify the design of MAM methods 

Poster 2020: Use of PASEF for Accelerated Protein Sequence Confirmation and de novo Sequencing with High Data Quality 

Poster 2020: Sensitive drug distribution measurements of an ADC with non-denaturing capillary SEC 

Poster 2020: Intact Protein Multi-Attribute Method (MAM) that Includes the Identification and Quantification of Protein Clipping Events 

Poster 2020: Enhanced detection of host cell proteins enabled by use of collisional cross section values 

Poster 2020: Peptide structure confirmation with isomer distinction based on molecular weight and collision cross section obtained with trapped ion mobility separation 

Poster 2020: Characterization of API impurities and degradation products by ion mobility LC-timsTOF Pro with parallel accumulation serial fragmentation (PASEF) 

Poster 2020: Novel High-Throughput MALDI-TOF MS Workflow for Screening of Different Analytes at Each Position on a Plate 

Poster 2020: Multiplexed Analytical Platform using Affinity Capture and MALDI MS Enables Novel Assay Development for Screening Biomarkers of Neurological Diseases 

Poster 2020: Trapped Ion Mobility Spectrometry (TIMS) enables differentiation of isobaric N-glycan isomers (by specific collisional cross sections) 

Poster 2020: Reproducibility of native SEC LC-MS intact mAb characterisation measurements 

Poster 2020: Assaying Protein / Ligand Binding with High-Resolution Native Mass Spectrometry

ASMS 2019

Poster 2019: Simultaneous Profile and Determination of Statin Composition in Various Media and Biological Matrices by Accurate Mass and High Resolution LC-QTOF-MS 

Poster 2019: CHO Cell Culture Media Profiling and Unknown Identification by Liquid Chromatography and Accurate Mass High Resolution Mass Spectrometry 

Poster 2019: Structural study of a PEGylated therapeutic protein by MALDI-ISD and ESI-QTOF 

Poster 2019: Streamlining mAb characterization with a PASEF based disulfide analysis workflow 

Poster 2019: Separation of Asp/IsoAsp Isobaric Peptides using Trapped Ion Mobility Spectrometry (TIMS) 

Poster 2019: The benefit of peptide CCS value prediction and experimental determination 

Poster 2019: A software platform for peptide synthesis quality control by both LC-free MALDI-TOF and LC-ESI-QTOF molecular weight determination 

Poster 2019: A software platform for the quality control of synthetic oligonucleotides 

Poster 2019: Optimized data analysis pipeline for MALDI imaging based tumor typing from FFPE tissue samples evaluated on six benchmark classification tasks 

Poster 2019: Predicting Lymph Node Metastasis in Endometrial Cancer by multi-modal mass spectrometry imaging 

Poster 2019: Mass Spectrometric In-Depth Proteome Analysis of the Kidneys from Rat Model of Diabetic Nephropathy 

Poster 2019: Metabolomics Characterization of Cell Culture Media by Ultrahigh Resolution LC-QTOF-MS Analysis 

Poster 2019: Analysis of Histones from HEK293 Cells using a QTOF with Trapped Ion Mobility and PASEF Workflows 

Poster 2019: Identification and Quantitation of Phosphopeptide Positional Isomers using Trapped Ion Mobility Spectrometry and PASEF

MALDI based protein characterization

 

For Research Use Only. Not for use in clinical diagnostic procedures.