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Advanced pharmaceutical and molecular imaging research

Bruker’s PharmaScan® MRI Scanner for Pharmaceutical and Molecular Imaging Research, designed for MRI applications on small animals

The PharmaScan® is a high field, easy-to-use and easy-to-install MR-system, which is very cost-effective at the same time. It is designed for MRI applications on small animals such as mice and rats in the field of routine pharmaceutical imaging as well as for biomedical and molecular imaging research.

Features:

  • MRI and MRS routine system for protons, optimized for small rodents (such as rats, mice, gerbils)
  • Actively shielded magnets at 4.7 T and 7 T allowing for easy and cost-efficient siting
  • 16 cm clear bore size with 72 mm free access for the animal
  • Actively shielded gradient system
  • Parallel imaging (GRAPPA) for almost all applications including EPI
  • High performance BGA-9 or BGA-9S gradients with highest amplitude, slew rates, shim strengths and duty cycles optimized for small animal imaging
  • No Faraday cage, which requires 25 m2 floor space will be necessary
  • Scalable AVANCETM III HD MRI RF architecture incorporates up to 4 receivers
  • AutoPac™ - Motorized, software controlled animal positioning system for routine animal handling and increased animal throughput
  • IntraGate -Self gated steady-state cardiac imaging package requiring no external sensor hardware and trigger devices
  • Phased-array RF coil technology for increased sensitivity and reduced scan times
  • MRI CryoProbe™ - Sensitivity increase up to a factor of 2.5 enables MRI of microscopic pathologies
  • ParaVision®6 - Fully intuitive software package for multi-dimensional MRI/ MRS data acquisition, reconstruction, analysis and visualization

Magnets

  • Field strengths from 4.7 to 7 T deliver maximum sensitivity for high speed and high resolution MRI applications
  • Minimum stray fields are guaranteed by Bruker's UltraShield™ technology enabling easy and cost efficient siting
     

Spectrometer

  • Spectrometer platform AVANCE™ III enables both MRI and MRS applications
  • Scalable architecture provides up to 4 parallel receiver channels
  • Real-time spectrometer control (optimization of acquisition parameters during scan)
  • Digital pre-emphasis and digital RF generation

Gradients

  • Standard actively shielded  gradient system
  • Integrated shim coils deliver optimal field homogeneity
  • Extra cooling produces unique duty cycle specifications
     

RF Coils

  • Volume resonators at a range of 23 mm up to 72 mm inner diameter
  • Active RF decoupling allows operation of independent transmit and receive coils
  • Multi-channel array coils enable parallel imaging applications
  • Integrated preamplifiers guarantee optimal sensitivity over a large dynamic range
  • Hardware recognition of RF coils automatically configures all relevant parameters

PharmaScan Gallery

Wide range of applications in preclincal MRI

ParaVision® software package provides a framework for multi-dimensional MRI/MRS data acquisition, reconstruction, analysis and visualization.
This basic software package is supplemented by several extension packages which offer additional experimental techniques or sophisticated post-processing algorithms.
 

  • Standard acquisition, reconstruction, data analysis and visualization
  • State-of-the-art 2D and 3D MR imaging techniques
  • Easy set-up with autoadjustments and localizer scans
  • Predefined application oriented protocols
  • Real-time display of acquired and reconstructed data
  • system status information informing scan progress
  • Ready-to-use protocols for ultra-fast imaging sequences including echo-planar imaging (EPI) techniques
  • On-line, off-line, reconstruction, including baseline correction, window multiplication and phase correction capabilities

LabScape

Service and Life Cycle Support

Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laborator.

Download LabScape Brochure