Food Intolerance
Lactose Intolerance
Lactose intolerance is very widespread worldwide, although there are significant differences depending on the region and population. About 5 to 15 % of Europeans cannot tolerate lactose. Lactose intolerance is rarest in northern Europe. In Africa or East Asia, however, 65 to over 90 % of adults are affected.
In case of this most common form of food intolerance, the enzyme lactase can no longer be formed in the intestines and lactase deficiency results. A distinction is made between primary and secondary lactose intolerance, depending on the cause of this decrease. In case of primary lactose intolerance, the decrease is genetically based and manifests itself starting at around 10 years of age.
In case of the acquired secondary form, lactase deficiency is the consequence of another disease. Due to lack of lactase, lactose contained in the food can no longer be digested and therefore reaches the small intestine in an undigested form. As a result symptoms such as abdominal pain, vomiting, diarrhea and flatulence, occur. Therefore, the presence of lactose intolerance should be considered and investigated after clarification of other organic causes in persons with these kinds of symptoms.
Products for diagnostics of food intolerance
Food intolerance can be easily detected by using molecular genetic methods directly from blood specimens. There is no need for time-consuming and uncomfortable patient testing.
Our test systems allow for fast and reliable detection of hereditary lactose intolerance.
The choice is yours: different technologies and test systems provide you with your individual results.
The test system GenoType LCT VER 1.0 is based on the user-friendly DNA•STRIP technology and reliably detects lactose intolerance.
The FluoroType® LCT VER 1.0 test is based on the innovative FluoroType® technology enabling the secure identification of primary lactose intolerance.
Product range
Your fluorescence-based test system for the reliable detection of primary lactose intolerance.
Your benefits with FluoroType® LCT VER 1.0
- Reliable result: Only genetically based lactose intolerance is detected. This makes it possible to differentiate it from acquired lactose intolerance, which is treatable in some cases.
- Rapid result: In contrast to complex function tests, the patient does not need to spend several hours under medical observation. Only a blood sample is needed for the determination.
- User-friendly: From amplification to detection, all steps are performed in the FluoroCycler®. Analysis and interpretation of results are then performed using a test-specific software. Your diagnostics therefore become even simpler and more reliable.
At a glance
Molecular genetic fluorescence-based test system for analysis of the genetically determined lactose intolerance
Starting material:
EDTA blood
DNA Isolation:
GXT Blood Extraction Kit VER 2.0 (with GenoXtract®)
Instrument for Amplification and Detection:
FluoroCycler® 12
FluoroCycler® XT
Technology:
FluoroType® technology
Downloads:
Your test system for the reliable detection of primary lactose intolerance by combined analysis of the polymorphisms C/T-13910 and G/A-22018 in the lactase gene
With GenoType LCT VER 1.0, simple and quick determination of genetically based primary lactose intolerance without any patient burden is possible. The test detects two polymorphisms in the lactase gene in positions –13910 and –22018, which are associated with primary lactose intolerance and thus makes definite detection possible.
Your benefits with GenoType® LCT VER 1.0
Reliable result: Only genetically based lactose intolerance is detected. This makes it possible to differentiate it from acquired lactose intolerance, which is treatable in some cases.
Rapid result: In contrast to complex function tests, the patient does not need to spend several hours under medical observation. Only a blood sample is needed for the determination.
Simple evaluation: Using an evaluation template, the test result can be read rapidly and easily.
At a glance
Molecular genetic assay for analysis of the genetically determined lactose intolerance
Starting material:
EDTA/Citrate blood
DNA Isolation:
GENO•CARD VER 1.0 or
GXT Blood Extraction Kit VER 2.0 (with GenoXtract®)
Technology:
DNA•STRIP technology
Downloads: