SKYSCAN 1275
Ultimate Ease-of-Use
Highlights
The desktop SKYSCAN 1275 is a real 3D X-ray microscopy power pack, designed for fast scanning of a wide range of samples. Thanks to the compact geometry and fast flat-panel detector the time to result can be as short as a few minutes. Just ideal for high throughput imaging.
The SKYSCAN 1275 comes furthermore with a high level of automation thus providing superior ease-of-use. Simply pushing the button at the control panel starts an auto-sequence of a fast scan, followed by reconstruction and volume rendering. All executed while the next sample is already being scanned. The optional 16-position sample changer even allows for unattended high throughput scanning.
The SKYSCAN 1275 is complemented by 3D.SUITE. This extensive software suite covers GPU-accelerated reconstruction, 2D/ 3D morphological analysis, as well as surface and volume rendering visualization.
Key Features
Push-Button XRM
Just insert a sample, manually or automatically, and get a complete 3D volume without any further interaction.
Push-Button XRM includes everything: automatic sample size detection, sample scanning, 3D reconstruction, and 3D volume rendering. Ideal for routine tasks, or operation by non-expert users!
You need full control? No problem, SKYSCAN 1275 offers all features.
Combined with a sample changer SKYSCAN 1275 even works 24/7.
Sample changer
SKYSCAN 1275 can optionally be equipped with an external 16-position sample changer to increase throughput for QC and routine analysis.
The sample changer accepts a variety of sample sizes, up to a diameter of 96 mm.
Samples can be can be easily replaced at any time without interrupting an ongoing scanning process. New samples are automatically detected, and LED‘s indicate the status for every scan: ready, scanning, done.
In-situ stages
The Bruker material testing stages are designed to perform compression experiments up to 4400 N and tensile experiments up to 440 N. All stages automatically communicate through the system’s rotation stage, without the need of any cable connections. Using the supplied software, scheduled scanning experiments can be set up.
Bruker's heating and cooling stages can reach temperatures of up to +80ºC, or 30ºC below ambient temperature. Just like the other stages, no extra connections are needed, and there is an automatic recognition of the stage. Using the heating & cooling stages, samples can be examined under non-ambient conditions, to evaluate the effect of temperature on the sample’s microstructure.
Highlighted Applications
Bone Applications
The SKYSCAN 1275 provides the bone research community with a solid solution for fast, high throughput and high-quality bone morphometry of animal models. The advanced cMOS flat panel camera cuts rodent morphometry scans to a tiny fraction of what scientists are used to with the first generation of osteoporosis research microCT scanners – we’re talking about 5 minutes only. Without compromise to resolution of the smallest rod-like mouse trabecular structures – nothing is lost. With the SKYSCAN 1275 you will publish more papers each year than with scan-slow microCT alternatives.
- Fast cMOS flat panel with ~2000 x 1500 pixel format, fastest scans less than 100 seconds (step and shoot).
- Effortless imaging of large bone samples not previously studied by microCT with fast throughput for research productivity.
- All rodent morphometry of trabecular and cortical bone is taken care of, with bone morphometry (ASBMR nomenclature) with comprehensive 3D and 2D parameters, and densitometry including BMD calibration references over a 2-32mm diameter size range.
- Optional sample changer for 16 preloaded samples makes large scale screening studies possible with thousands of mouse or zebrafish bones for trabecular and cortical bone parameters.
Dentistry
Teeth are a step up from rodent bones in thickness and mineral density, requiring an appropriate microCT solution. The SKYSCAN 1275 is this solution, effortlessly imaging small and large teeth, even fossil ones subject to mineral diagenesis. And this capability in a user-friendly high-throughput desktop instrument. With the SKYSCAN 1275 you will publish more papers each year than with scan-slow uCT alternatives.
- Fast cMOS flat panel with ~2000 x 1500 pixel format, fastest scans less than 100 seconds (step and shoot).
- The large x-ray camera with excellent high energy sensitivity makes most vertebrate teeth scannable as well as prostheses and dental implant materials.
- Optional sample changer for 16 preloaded samples makes large scale dental screening and endodontic before-and-after canal treatment studies straightforward.
- Bone morphometry (ASBMR nomenclature) with comprehensive 3D and 2D parameters, with densitometry including BMD calibration references over a 2-32mm diameter size range.
Plant and Animal Biology
MicroCT is exceptionally good at visualization of the finest details of the internal structure of biological tissue. It is already a well-established tool in botany and zoology. The SKYSCAN 1275 is a unique compact and user-friendly desktop scanner with a powerful flat panel camera allowing – in a nutshell – faster scanning of bigger samples than before. Its fast, user-friendly scanning with a large field of view removes barriers to the advantageous use of this non-destructive 3D imaging technique to more and more scientists and disciplines.
- Fast evaluation of the internal structures of fruits, seeds, insects, corals and marine organisms.
- Digitize a 3D volume of valuable samples for further visualization or cataloging.
- Multiple sample scanning possible due to the batch-scanning mode and optional sample changer, effectively reducing down-time.
- Comprehensive 3D image analysis capability including morphometry and densitometry, 3D registration, segmentation and advanced image processing methods.
Application Gallery
3D render of a rat bone, showing the trabecular network color-coded for local thickness.
Volume rendered 3D model of a lemon.
Orthogonal slices through a human extracted molar with polymer cap, scanned at 10 µm voxel size.
3D render of a sheep distal femur with 2 titanium implants.
Volume rendered 3D models of trabecular bone upon different compression rates (compression increasing from left to right).
Volume rendered 3D model of a human tooth, scanned at 15 µm voxel size after root canal preparation, virtually cut to show the removed material in red and drilling debris in green.
Maximum intensity projection of a zebrafish scanned at 8 µm voxel size.
Orthogonal slices through a rat brain, scanned after lugol staining at 10 µm voxel size.
3D model of a rat heart stained in Lugol solution, scanned at 7 µm voxel size.
Orthogonal slices through a round courgette, scanned at 50µm voxel size.
Volume rendered 3D model of a Ca-phosphate-protein scaffold, scanned at 6.3 µm voxel size.
Orthogonal slices through a human tooth with steel implant.
3D model of a zebrafish, scanned at 8 µm voxel size after PTA staining.
Volume rendering of a rat bone trabecular network, scanned at 26 µm voxel size. The image on the right represents a color-coding of the trabecular thickness and separation.
SKYSCAN 1275 Specifications
Feature |
Specification |
Benefit |
X-ray source |
40 – 100 kV 10 W < 5 µm spot size at 4 W |
Maintenance-free sealed X-ray source Fast scans for QC, or 4D XRM |
X-ray detector |
Active pixel CMOS flat-panel 3 MP (1944 x 1536) 75 µm pixel size |
Excellent signal-to-noise Large Field-of-View |
Object size |
96 mm diameter 120 mm height |
Capable to scan a large range of sample sizes |
Sample changer (optional) |
16 samples up to 50 mm diameter 8 samples up to 96 mm diameter External access |
Unattended high throughput Any combination of large and small samples Add/remove samples at any time without interrupting the actual scan |
Dimensions |
W 1040 mm x D 665 mm x H 400 mm Weight 170 kg |
Space-saving desktop system that fits in every lab |
Power supply |
100-240V AC, 50-60Hz, 3A max. |
Minimum installation requirements, a standard power supply suffices |
POSITION, SCAN, RECONSTRUCT and ANALYZE
Bruker XRM solutions include all software needed to collect and analyze data. An intuitive graphical user interface with user guided parameter optimization support both expert and novice users. By using the latest GPU powered algorithms, reconstruction time is substantially reduced. CTVOX, CTAN and CTVOL combine to form a powerful suite of software for both qualitative and quantitative analysis of models.
Measurement Software:
SKYSCAN 1275 – Instrument control, measurement planning and collection
Reconstruction Software:
NRECON – Transforms the 2D projection images into 3D volumes
Analysis Software:
DATAVIEWER – Slice-by-slice inspection of 3D volumes and 2D/3D image registration
CTVOX – Realistic visualization by volume rendering
CTAN – 2D/3D image analysis & processing
CTVOL – Visualization of surface models to export for CAD or 3D printing
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