Proteomics Content Collection

Overview

Fuel your discoveries with next-generation protein insights and propel them into the future. Dive deeper than ever before, from exploring intricate protein networks in tissues to deciphering the secrets of single-cell function. Embrace the power of 4D-Proteomics™, your fast track to groundbreaking insights in protein interactions, post-translational modifications, and cellular function.

ASMS 2025

timsOmni™

timsUltra AIP

proteoElute™

PepSep^®Advanced

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Introducing timsOmni™

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timsOmni™ - An eXtreme leap in deep proteoform sequencing and advanced structural elucidation

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proteoElute - Innovation You Can Trust, Precision You Can Rely On

Resources

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timsTOF Ultra

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timsTOF Ultra – Live from the Lab

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CaptiveSpray

Embracing Spatial Proteomics

The spatial distribution of biomolecules on tissue encodes high value information on cell communication or evolution, which can be closely related to disease progression like cancer development. The MALDI Guided SpatialOMx® approach - enabled by the timsTOF fleX series – allows insight on molecular distribution patterns and drives cellular characterization and visualization. Perform deep omics analysis on regions of interest to gain insight into biological mechanisms or advanced biomarker/target discovery by removing background from surrounding tissue.

Discover the next proteomics step

timsTOF Ultra

Discover the extraordinary capabilities of the timsTOF Ultra mass spectrometer and CaptiveSpray Ultra ion source for groundbreaking omics research. With their combined force, they unleash unparalleled sensitivity, allowing you to conquer samples, detect, characterize and quantify low-abundance peptides, and make groundbreaking discoveries.

Bruker ProteoScape™

Bruker ProteoScape™ (BPS) is the comprehensive proteomics data analysis platform utilizing real-time data streaming to monitor system suitability. It provides analysis of dda-PASEF (including de novo sequencing with BPS Novor) and dia-PASEF® workflows with TIMS DIA-NN and TIMScore™ to increase the accuracy and confidence in your proteomics results. BPS is a combined hardware and software ecosystem for existing and new timsTOF customers.

TwinScape™

With TwinScape™, customers not only will be able to monitor their QC runs, giving for the first time, the possibility to compare instrument performance across experiments, across time, and across their lab, but they will also have the possibility to proactively monitor their system performance via a web application, anytime, anywhere, allowing our customers to ensure optimal device performance while running their precious samples. This will also allow Bruker’s Service Engineers to significantly increase effectiveness, reducing downtime, allowing full potential performance.

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CaptiveSpay 2 and CaptiveSpray Ultra 2

CaptiveSpray 2 and CaptiveSpray Ultra

Specifically engineered for timsTOF systems, the CaptiveSpray 2 boasts exceptional performance capabilities that elevate your experiments to greater levels. Exclusively crafted for the timsTOF Ultra 2, the CaptiveSpray Ultra 2 pushes ionization efficiency to uncharted territories, delivering an unmatched sensitivity that exceeds all expectations.

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Single Cell Proteomics

Get ready to transcend the limitations of single-cell proteomics, maximize your understanding of cellular heterogeneity and pave the way for groundbreaking discoveries.

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Plasma Proteomics

Explore the potential of mass spectrometry for unbiased large-scale biomarker discovery and personalized medicine with plasma proteomics. Mass spectrometry has unlocked new possibilities for studying the plasma proteome, i.e. proteins from blood which connect almost all tissues. By using this technology, researchers can identify and quantify proteins and post-translational modifications at high sensitivity, confidence, and scale.

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Immunopeptidomics

To determine the identity of even the smallest amounts of biomolecules, timsTOFs leverage a powerful combination of shape-resolving ion mobility and a high-resolution mass analyzer. This allows studying with high confidence the immunopeptidome, traces of peptides decorating cells that our immune system interrogates to distinguish friend and foe, providing a new perspective on diseases like infections, autoimmunity, or cancer.

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Targeted Protein Degraders

Protein degraders are a promising class of drugs that have gained significant attention in recent years due to their potential to treat previously "undruggable" targets in diseases such as cancer. However, the development of these drugs come with its own set of challenges and can benefit significantly from modern mass spectrometry (MS) analysis.

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For Research Use Only. Not for use in clinical diagnostic procedures.