Mass spectrometry imaging (MSI) of clinical samples can be daunting due to the presence of high abundance, uninteresting molecules in the tissues or due to the way that the samples are processed and preserved. For example, the presence of hemoglobin from red blood cells can suppress the signal from other, lower abundance proteins that may be more relevant to the disease being studied.
A second challenge is that most clinical tissue samples are banked as formalin fixed, paraffin embedded tissue specimens, which present difficulties for the detection and imaging of biomolecules.
In this webinar, we will present new sample preparation strategies for overcoming these issues and producing high quality MSI data.
Erin H. Seeley
Mass Spectrometry Imaging Facility Director
University of Texas at Austin, USA
For Research Use Only. Not for use in clinical diagnostic procedures.