This research highlight features Francesco Simone Ruggeri, PhD, a faculty member in the Organic and Physical Chemistry Chair Groups at Wageningen University. Dr. Ruggeri details his contributions to the photothermal AFM-IR technique and its applications: publishing the first AFM-IR study on protein aggregation, developing single-molecule and in-liquid imaging and spectroscopy, demonstrating the use of microfluidic sprays to prepare samples, and more.
“Using AFM-IR was a perfect tool to study [protein aggregates], because AFM-IR allowed us to probe one of these aggregates at the time and study chemical properties, things that were not possible with any other technology before.”
ABOUT THE RESEARCHER:
Dr. Simone Ruggeri is an Associate Professor, leading the Laboratory of Nanoscale Microscopy and Spectroscopy within the Organic and Physical Chemistry Chair Groups at Wageningen University in the Netherlands.
FIELD OF STUDY:
Dr. Ruggeri has a strong background in studying proteins using nanoscale imaging and spectroscopy, and he and his group have more recently expanded their AFM-IR contributions to the field of materials science, with studies on perovskites, polymers, and micro-/nanoplastics