This latter point is particularly pertinent given the explosion in the number of new synthetic cannabinoids hitting the drug scene. Using a standardized protocol, new drug substances can be easily added to the database. Given that TargetScreener HR collects ‘all of the data, all of the time’, all data files contain all the information required to retrospectively re-screen a previously analyzed sample when new compounds have been added to the database.
Should a positive id still not be achieved, the mass spectra of an unknown peak will contain pseudo molecular ion accurate mass information, true isotopic ion (TIP – registered trade mark) for elemental composition and accurate mass fragment ions thus allowing the best chance of elucidating a chemical structure.
Furthermore, significant advances within Bruker’s OTOF instruments have resulted in systems which are both very sensitive and possess a large linear dynamic range in their response thus making them eminently suitable for quantitative studies.
Collectively, these benefits make TargetScreener HR the most powerful tool for in-depth forensic analysis.