ASMS 2022 - Bruker's eXceed Symposia and Breakfast Workshops

Enhancing Workflow Capabilities for Translational Mass Spectrometry

Introduction

Introduction

Welcome to Bruker's activities during ASMS 2022 taking place from June 5 - 9, 2022, in Minneapolis. Be aware that all our activities are on site only.

 

Our events will start on Sunday, June 5, at 8:30 am with our eXceed Symposia in the Hyatt Regency. Please see details on the agenda below.

 

From Monday to Wednesday you can hear about our latest technologies in our Breakfast Workshops focusing on Proteomics, BioPharma and Imaging. The Breakfast Workshosp will take place at 7:00 am in the Minneapolis Convention Center, Room 200 DE on the second level.

 

And be sure to also visit our Hospitality Suite in the Hilton Minneapolis and stop by our Bruker Booth #407 in Halls B and C to see our instruments displayed.

eXceed Symposia

eXceed Symposia
Enhancing Workflow Capabilities for Translational Mass Spectrometry 
Sunday, June 5, 2022

Sunday, June 5, 2022, 8:30 am – 1 pm CDT
Hyatt Regency Minneapolis
NorthStar Ballroom, Greenway Ballroom DEFG and BCHI
1300 Nicollet Mall
Minneapolis, MN 55403

 

Plenary Session: Enhancing Workflow Capabilities for Translational Mass Spectrometry

08:30-08:45​ Welcome & Introduction
Rohan A. Thakur, Ph.D., President, Life Sciences Mass Spectrometry Division, Bruker, Fällanden, Switzerland

​08:45-09:05​ Proteomics at Scale – Actionable Insights to Drug Discovery & Translational Research
Ashok Dongre, Ph.D., Director & Head Proteomics, Bristol-Myers Squibb, USA

09:05-09:25​ Single cell based diagnostics: translation imaging mass spectrometry
Prof. Ron Heeren, Ph.D., Director and Division Head Imaging Mass Spectrometry, Maastricht MultiModal Molecular Imaging Institute, M4i, Maastricht University, Maastricht, Netherlands

09:25-09:45 Benefits of Collisional Cross Section Assisted Precursor Selection for Cross-linking Mass Spectrometry and Glycoproteomics
Prof. Albert J. R. Heck, Ph.D., Distinguished Faculty Professor, Utrecht University, Scientific Director, Netherlands Proteomics Centre, Utrecht, Netherlands

09:45-10:15​ Break

10:15​ Start of Breakout Sessions

 

Breakout #1 Proteomics – Enhancing Workflow Capabilities of Single Cell and Translational Proteomics

10:15-10:30​ Analysis of a single cell to the plasma proteome​
Chris Adams​, Ph.D., Business Development Director, Global Bioinformatics, Life Science Mass Spectrometry, Bruker Daltonics, Billerica, MA, USA

10:30-10:55 Nanoparticle-based enrichment coupled with Bruker timsTOF Pro 2 platform facilitates unbiased and reproducible plasma proteomics for biomarker discovery at scale
Bruce Wilcox, Ph.D., VP Proteomics, PrognomiQ, San Mateo, CA, USA

10:55-11:20​ High sensitivity and deep coverage immunopeptidomics on the timsTOF Pro 2 and SCP
Prof. Stefan Tenzer​, Ph.D., Head of Mass Spectrometry Core Facility, University Medical Center, Mainz, Germany

11:20-11:45​ Unraveling multi-level tissue heterogeneity at single-cell and low input using the timsTOF SCP
Claudia Ctortecka​, Ph.D., Postdoctoral Fellow, Carr Laboratory, Broad Institute of MIT and Harvard, Cambridge, MA, USA

​11:45-12:00​ Break​

12:00-12:25​ Boosting proteome depth of coverage by ion mobility fractionation in combination with PASEF approaches on a TIMS-QTOF instrument
Stanley Stevens​, Ph.D., Associate Professor, Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, FL, USA 

12:25​-12:50 A Fit-for-Purpose Approach to Detect Amino Acid Substitutions in Shotgun Proteomics 
Matthew Champion, Ph.D., Associate Professor, Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN, USA

 

Breakout #2 Pharma/BioPharma - Enhancing Workflow Capabilities in Pharma and Biopharma

10:15-10:30​ Introduction ​
Mike Greig, Ph.D., Director, Pharma/BioPharma Americas, Bruker Daltonics, Billerica, MA, USA ​

10:30-11:05 Large-Scale Mass Spectrometry Profiling for Accelerated Biomarker Discovery
Jeramie Watrous, Ph.D., Co-Founder and Head of Analytical R&D, Sapient, San Diego, CA, USA

11:05-11:40 Mapping progressively larger RNAs without front-end separations
Dan Fabris​, Ph.D., Harold S. Schwenk Sr. Distinguished Chair in Chemistry, Department of Chemistry, University of Connecticut, Mansfield, CT, USA

11:40-12:00 Break​

12:00-12:30 High-Throughput Host Cell Protein Analysis in Industrial Biotechnology​
Christian Jörgensen, Ph.D., Novozymes A/S, Bagsvaerd, Denmark​

12:30-1:00 Rapid Characterization of Bispecific Antibodies using Phase Appropriate LC-MS Strategy
Na Parra, Ph.D., Co-Founder & Executive Vice President of Marketing, LiVeritas Biosciences, South San Francisco, CA, USA 

 

Breakout #3 Imaging - Enhancing Workflow Capabilities through Spatial Contextualization​

10:15​-10:25 Introduction
Mike Easterling​, Ph.D., Business Unit Manager, Imaging/MRMS, Bruker Daltonics, Billerica, MA, USA

10:25-10:45​ Behind the scenes with the PC-mass tag developers
Mark Lim​, Ph.D., Executive Vice President and Chief Scientific Officer, AmberGen Inc., Watertown, MA, USA

10:45-11:15​ First Impressions of the MALDI HiPLEX-IHC Workflow
Reid Groseclose, Ph.D., Director/GSK Fellow, GlaxoSmithKline, Philadelphia, PA, USA

11:15-11:45​ Maximizing Data Generation for Rare Diseases in Biopharma
Joey Latham, Ph.D., Senior Director, Bioanalytical Science at PTC Therapeutics, Mountain View, CA, USA

11:45​-12:00 Break​

12:00-12:30​ Preclinical Applications of Targeted Drug and Protein Imaging
John Bowling, Ph.D., Staff Scientist, Analytical Technologies Center, St. Jude Children's Research Hospital, Memphis, TN, USA

12:30-1:00​ Multiplexing Spatial Proteomics of Matrix Biology in Human Health and Disease
Peggi Angel, Ph.D., Associate Professor, Department of Cell & Molecular Pharmacology & Experimental Therapeutics, Medical University of South Carolina, Charleston, SC, USA

Ashok Dongre, Ph.D., Director & Head Proteomics, Bristol-Myers Squibb, USA

Proteomics at Scale – Actionable Insights to Drug Discovery & Translational Research

Prof. Ron Heeren, Ph.D., Director and Division Head Imaging Mass Spectrometry, Maastricht MultiModal Molecular Imaging Institute, M4i, Maastricht University, Maastricht, Netherlands

Single cell based diagnostics: translation imaging mass spectrometry

Prof. Albert J. R. Heck, Ph.D., Distinguished Faculty Professor, Utrecht University, Scientific Director, Netherlands Proteomics Centre, Utrecht, Netherlands

Benefits of Collisional Cross Section Assisted Precursor Selection for Cross-linking Mass Spectrometry and Glycoproteomics

Bruce Wilcox, Ph.D., VP Proteomics, PrognomiQ, San Mateo, CA, USA

Nanoparticle-based enrichment coupled with Bruker timsTOF Pro 2 platform facilitates unbiased and reproducible plasma proteomics for biomarker discovery at scale

Prof. Stefan Tenzer​, Ph.D., Head of Mass Spectrometry Core Facility, University Medical Center, Mainz, Germany

High sensitivity and deep coverage immunopeptidomics on the timsTOF Pro 2 and SCP

Claudia Ctortecka​, Ph.D., Postdoctoral Fellow, Carr Laboratory, Broad Institute of MIT and Harvard, Cambridge, MA, USA

Unraveling multi-level tissue heterogeneity at single-cell and low input using the timsTOF SCP

Stanley Stevens​, Ph.D., Associate Professor, Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, FL, USA

Boosting proteome depth of coverage by ion mobility fractionation in combination with PASEF approaches on a TIMS-QTOF instrument

Matthew Champion, Ph.D., Associate Professor, Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN, USA

A Fit-for-Purpose Approach to Detect Amino Acid Substitutions in Shotgun Proteomics 

Jeramie Watrous, Ph.D., Co-Founder and Head of Analytical R&D, Sapient, San Diego, CA, USA​

Large-Scale Mass Spectrometry Profiling for Accelerated Biomarker Discovery

Dan Fabris​, Ph.D., Harold S. Schwenk Sr. Distinguished Chair in Chemistry, Department of Chemistry, University of Connecticut, Mansfield, CT, USA

Mapping progressively larger RNAs without front-end separations

Na Parra, Ph.D., Co-Founder & Executive Vice President of Marketing, LiVeritas Biosciences, South San Francisco, CA, USA 

Rapid Characterization of Bispecific Antibodies using Phase Appropriate LC-MS Strategy

Mark Lim​, Ph.D., Executive Vice President and Chief Scientific Officer, AmberGen Inc., Watertown, MA, USA

Behind the scenes with the PC-mass tag developers

Reid Groseclose, Ph.D., Director/GSK Fellow, GlaxoSmithKline, Philadelphia, PA, USA

First Impressions of the MALDI HiPLEX-IHC Workflow

Joey Latham, Ph.D., Senior Director, Bioanalytical Science at PTC Therapeutics, Mountain View, CA, USA

Maximizing Data Generation for Rare Diseases in Biopharma

John Bowling, Ph.D., Staff Scientist, Analytical Technologies Center, St. Jude Children's Research Hospital, Memphis, TN, USA

Preclinical Applications of Targeted Drug and Protein Imaging

Peggi Angel, Ph.D., Assistant Professor, Department of Cell & Molecular Pharmacology & Experimental Therapeutics, Medical University of South Carolina, Charleston, SC, USA

Multiplexing Spatial Proteomics of Matrix Biology in Human Health and Disease

Breakfast Workshop Proteomics

Breakfast Workshop Proteomics
Enhancing Workflow Capabilities of Single Cell and Translational Proteomics
Monday, June 6, 2022, 7:00 am CDT​

Minneapolis Convention Center
Room 200 DE
1301 Second Ave S
Minneapolis, MN 55403​

7:00-7:15​ Welcome and introduction
Chris Adams​, Ph.D., Business Development Director, Global Bioinformatics, Life Science Mass Spectrometry, Bruker Daltonics, Billerica, MA, USA

7:15​-7:30 Medium Depth High Throughput Proteomics Profiling using dia-PASEF for agricultural and biological fluid applications in a core facility 
Brett Phinney​, Ph.D., Director Proteomics Core, Genome Center, University of California, Davis, CA, USA - Abstract

7:30​-7:45 4D Proteomic Profiling of 200 Individuals: A High Throughput Workflow from Sample Preparation, dia-PASEF and PASER-MS to Profiling
Qin Fu​, Ph.D., Director, High Throughput Center, Advanced Clinical Biosystems Research Institute, Smidt Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA - Abstract and Bio

7:45​-8:00 Deep and Unbiased Plasma Proteomics Analysis of Alzheimer’s and Mild Cognitive Impairment Subjects with a Novel Multi-nanoparticle Approach
Mahdi Zamanighomi​, Ph.D., Principal Machine Learning Researcher, Seer, Inc., Redwood City, California, USA - Bio

8:00-8:15 ​Making a Smart-Instrument: APIo and Bidirectional Communication 
Patrick Ty Garrett​, Graduate student, Dr. John Yates Lab, The Scripps Research Institute, La Jolla, CA, USA - Abstract and Bio

Breakfast Workshop Pharma/BioPharma

Breakfast Workshop Pharma/BioPharma
Enhancing Workflow Capabilities in Pharma and BioPharma
Tuesday, June 7, 2022, 7:00 am CDT​

Minneapolis Convention Center
Room 200 DE
1301 Second Ave S
Minneapolis, MN 55403​

7:00-7:10 Welcome and introduction
Mike Greig​, Ph.D., Director, Pharma/BioPharma Americas, Bruker Daltonics, Billerica, MA, USA ​

7:10-7:35 One-Pot Exosome Proteomics Enabled by a Photocleavable Surfactant
Kevin Buck, Graduate Student, Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA

7:35-8:00 High throughput chemo-proteomic approaches for mapping the degradable proteome
Katherine Donovan, Ph.D., Senior Scientist, Proteomics Group Lead,  Eric Fischer Lab, Dana-Farber Cancer Institute, Boston, MA, USA - Abstract

8:00-8:15 Streamlined & automated sample processing for in-depth proteomic analyses
Garwin Pichler, Ph.D., CEO, PreOmics GmbH, Planegg/Martinsried, Germany - Abstract

Breakfast Workshop Imaging

Breakfast Workshop Imaging
Enhancing Workflow Capabilities through Spatial Contextualization
Wednesday, June 8, 2022, 7:00 am CDT​

Minneapolis Convention Center
Room 200 DE
1301 Second Ave S
Minneapolis, MN 55403​

7:00-7:05 Welcome and introduction
Kate Stumpo​, Business Development Manager, SpatialOMx, Bruker Daltonics,  Billerica, MA, USA

7:05-7:25 ​Simultaneous Quantitation of Multiple Analytes with Mass Spectrometry Imaging
Sylwia Stopka, Ph.D., Postdoctoral Fellow, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA - Abstract and Bio

7:25-7:45​ Visualizing neurodegenerative diseases with multiple layers of biochemical detail
Prof. Per Andrén​, Ph.D., Medical Mass Spectrometry, Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden - Abstract and Bio

7:45-8:05​ Unraveling the spatial lipidome using gas-phase ion/ion reactions​
Boone Prentice​, Ph.D., Assistant Professor, Department of Chemistry, University of Florida, Gainesville, FL, USA - Abstract and Bio

8:05 Live Q&A​

 

For Research Use Only. Not for use in clinical diagnostic procedures.