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Bruker at ASMS 2024

June 2 - 6, 2024

Anaheim, CA, USA

Where Innovation Takes Center Stage

Prepare to be transported to the heart of innovation at ASMS 2024 with Bruker. Experience cutting-edge advancements in mass spectrometry technology while soaking in California's vibrant spirit.

eXceed Symposia 2024 | Breakfast Workshops | Booth #312

Explore the latest breakthroughs in Bruker mass spectrometry across:

  • 4D-Proteomics™
  • 4D-Lipidomics™ and 4D-Metabolomics™
  • Imaging including SpatialOMx®
  • Pharma and Biopharma
  • Applied Markets — food and beverage, environmental testing, and industrial applications

Book a Meeting with a Bruker Expert!

We invite you to book a 1:1 meeting with a member from our Sales, Applications, and Service Teams to discuss the latest news and developments.

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eXceed Symposia - Multiomics solutions for the post-genomic era
June 2, 2024
8:30 am - 1:05 pm PST
Westin Anaheim, 1030 West Katella Avenue, Anaheim, CA, USA
Plenary session: Annabella Ballroom A-B

Albert Heck
Ph.D., Professor of Chemistry and Pharmaceutical Sciences, Utrecht University and Scientific Director, Netherlands Proteomics Center, Utrecht, Netherlands

Blaine R. Roberts
Ph.D., Associate Professor and Principal Investigator, Emory University School of Medicine, Atlanta, GA, USA

Lingjun Li
Ph.D., Vilas Distinguished Achievement Professor, Charles Melbourne Johnson Distinguished Chair Professor, University of Wisconsin-Madison, WI, USA

8:30 am Welcome and introduction 
Rohan A. Thakur, Ph.D., President, Life Sciences Mass Spectrometry Division, Bruker, Fällanden, Switzerland

8:50 am It is in our blood, protein-centric approaches to tackle your antibody repertoires
Albert Heck, Ph.D., Professor, Chemistry and Pharmaceutical Sciences, Utrecht University and Scientific Director, Netherlands Proteomics Center, Utrecht, Netherlands

9:15 am From Blood to the Brain; how integrated spatial and LC-based data advance our understanding of neurodegenerative diseases
Blaine R. Roberts, Ph.D., Associate Professor and Principal Investigator, Emory University School of Medicine, Atlanta, GA, USA

9:40 am Probing Cellular Heterogeneity via Spatially Resolved Omics and Mass Spectrometry Imaging
Lingjun Li, Ph.D., Vilas Distinguished Achievement Professor, Charles Melbourne Johnson Distinguished Chair Professor, University of Wisconsin-Madison, WI, USA

10:05 am After the plenary session, the meeting will break into three parallel sessions.  

register here

Breakout Session Proteomics
Annabella Ballrooms A-B

Nikolai Slavov
Ph.D., Director, Parallel Squared Technology Institute and Professor, Northeastern University, Boston, MA, USA

Roman Fischer
Ph.D., Associate Professor, University of Oxford, Centre for Medicines Discovery (CMD), Target Discovery Institute (TDI), CAMS Oxford Institute (COI), Oxford, UK

Lindsay Pino
Ph.D., Co-Founder and CTO, Talus Bio, Seattle, WA, USA

Ileana Cristea
Ph.D., Associate Professor, Princeton University, NJ, USA

10:30 am Introduction
Daniel Hornburg, Ph.D., Vice President, Biomarkers and Precision Medicine, Bruker Scientific LLC, Billerica, MA, USA

10:45 am High throughput protein analysis of single cells and subcellular organelles reveals regulatory principles
Nikolai Slavov, Ph.D., Director, Parallel Squared Technology Institute and Professor, Northeastern University, Boston, MA, USA

11:10 am Precision proteomics in human disease
Roman Fischer, Ph.D., Associate Professor, University of Oxford, Centre for Medicines Discovery (CMD), Target Discovery Institute (TDI), CAMS Oxford Institute (COI), Oxford, UK

11:35 am Profiling oncogenic transcription factors using mass spectrometry proteomics
Lindsay Pino, Ph.D., Co-Founder and CTO, Talus Bio, Seattle, WA, USA

12:00 pm Break

12:15 pm Intra- and inter-cellular communication in 2D and 3D cell models of health and disease
Ileana Cristea, Ph.D., Associate Professor, Princeton University, NJ, USA

register here

Breakout Session MALDI Imaging/SpatialOMx®
Annabella Ballroom C-D

Carsten Hopf
Ph.D., Professor and Head of CeMOS, Mannheim - M2Aind Industry Consortium, Mannheim, Germany

Mengze Stettler-Zhang
Graduate Student, University of Zürich and ETH Zurich, Zurich, Switzerland

Brian Hoffman
Ph.D., Director, Mass Spectrometry Services and Protein Sciences, The Jackson Laboratory, Bar Harbor, ME, USA

Jake Dressman
Graduate Student, Medical University of South Carolina, Charleston, SC, USA

Mark Lim
Ph.D., Executive VP and CSO, AmberGen, Waltham, MA, USA

Erin Seeley
Ph.D., Director, Mass Spectrometry Imaging Facility, University of Texas, Austin, TX, USA

10:30 am Introduction
Kate Stumpo, Ph.D., Senior Market Manager Imaging Global, Bruker Scientific LLC, Billerica, MA, USA

10:35 am New instrumentation for biomedical SpatialOMx applications
Carsten Hopf, Ph.D., Professor and Head of CeMOS, Mannheim - M2Aind Industry Consortium, Mannheim, Germany

10:55 pm 120-plex MALDI-IHC recapitulates tissue structures and reveals diverse spatial features of endometrial cancer
Mengze Stettler-Zhang, Graduate Student, University of Zurich and ETH Zurich, Zurich, Switzerland

11:15 am Integrated multi-omics approaches for the analysis of lung adenocarcinoma
Brian Hoffman, Ph.D., Director, Mass Spectrometry Services and Protein Sciences, The Jackson Laboratory, Bar Harbor, ME, USA

11:35 pm Single-Cell Omni-Omics (SC-OO): Analysis of Captured Single Cells by multi-modal MALDI-IMS
Jake Dressman, Graduate Student, Medical University of South Carolina, Charleston, SC, USA

12:00 pm Break

12:15 am Unparalleled Spatial Multiomics at the Tissue and Single-Cell Level with MALDI HiPLEX-IHC
Mark Lim, Ph.D., Executive VP and CSO, AmberGen, Waltham, MA, USA

12:35 pm Integration of Multiplexed Multi-omic Imaging for a Deeper Understanding of the Tumor Microenvironment
Erin Seeley, Ph.D., Director, Mass Spectrometry Imaging Facility, University of Texas, Austin, TX, USA

register here

Breakout Session Multiomics
Gloriana A-C

Hans Wessels
Ph.D., Proteomics Scientist, Radboud University, Nijmegen, Netherlands

David Healey
Vice President of Data Science and Machine Learning, Enveda Biosciences, Salt Lake City, USA

Mo Jain
Ph.D., Founder and CEO, Sapient, San Diego, CA, USA

10:30 am Introduction
Erica Forsberg, Ph.D., Vice President, Metabolomics, AMER and APAC, Bruker Scientific LLC, Billerica, MA, USA
Matt Lewis, Ph.D., Vice President, Metabolomics, EMEA, Bruker UK Ltd., Coventry, UK
Klaus Lindpaintner, Ph.D., Vice President, Glycobiology Solutions, Bruker Scientific LLC, Billerica, MA, USA

10:45 am Glycan database-free real-time analysis of dda-PASEF glycoproteomics data using GlycoScape software and the Myriad algorithm 
Hans Wessels, Ph.D., Proteomics Scientist, Radboud University, Nijmegen, Netherlands

11:10 am 4D-Lipidomics™ - enhanced deep lipidome coverage and profiling in clinical specimens
Laura Bindila, Ph.D., Head of Clinical Lipidomics Unit, Institute of Physiological Chemistry, University Medical Center Mainz, Germany

11:35 am Advances in Leveraging Unannotated Data and Machine Learning for Metabolite Structure Prediction
David Healey, Vice President of Data Science and Machine Learning, Enveda Biosciences, Salt Lake City, USA

12:00 pm Break

12:15 pm High throughput mass spectrometry for next-generation multi-omics biomarker discovery
Mo Jain, Ph.D., Founder and CEO, Sapient, San Diego, CA, USA

12:40 4D-Lipidomics™ in a Core Facility
Kari Basso, Ph.D., Director of Mass Spectrometry Research and Education, University of Florida, Gainesville, FL, USA

register here

Breakfast Workshops

Breakfast Workshop Proteomics
Monday, June 3, 2024
7:00 am PST

Anaheim Convention Center, 800 W Katella Ave, Anaheim, CA, USA
Room: 208AB

Discover new biomedical insights through the lens of 4D-Proteomics™. From single cell to neoantigen discovery and large scale plasma studies, we will discuss end-to-end solutions that provide critical insights into cellular processes and support personalized medicine research.

Download the agenda here

 

Breakfast Workshop Metabolomics/Lipidomics
Monday, June 3, 2024
7:00 am PST

Anaheim Convention Center, 800 W Katella Ave, Anaheim, CA, USA
Room: 202AB

At our Breakfast Workshop, we’ll delve into the fascinating world of metabolomics and lipidomics that unlock the secrets of cellular processes through the comprehensive analysis of metabolites and lipids. These fields are revolutionizing our understanding of the biochemical pathways that fuel our bodies, much like a nutritious breakfast powers our day. Join us as we explore how these molecular insights are shaping the way we understand biological mechanisms of health and disease.

Download the agenda here

 

Breakfast Workshop Pharma
Tuesday, June 4, 2024
7:00 am PST

Anaheim Convention Center, 800 W Katella Ave, Anaheim, CA, USA
Room: 208AB

Join your Pharma colleagues and learn about the latest high sensitivity applications for advancing drug discovery.

Download the agenda here

 

Breakfast Workshop MALDI Imaging/SpatialOMx®
Wednesday, June 5, 2024
7:00 am PST

Anaheim Convention Center, 800 W Katella Ave, Anaheim, CA, USA
Room: 208AB

You no longer have to dream about how to make your MALDI Imaging methods multimodal. Our breakfast workshop will feature cutting edge research for spatial analysis.

Download the agenda here

register here

Applied Breakfast Workshops

Innovative Chromatography-Free Analytical Techniques for Advanced Polymer Characterization and Manufacturing Optimization
Monday June 3, 2024
7:00 am - 8:00 am

Anaheim Convention Center, 800 W Katella Ave, Anaheim, CA, USA
Room: 210D 

Mass spectrometry (MS) plays a crucial role in polymer analysis, enabling comprehensive assessment of structure, composition, additives, and molecular weight distribution. However, traditional MS methods often necessitate chromatography for sample separation.  This workshop focuses on the streamlined various Chromatography FREE approaches including DART, which analyzes complex polymeric materials without prior preparation, utilizing hot metastable He atoms to induce thermal desorption and degradation, followed by ionization for analysis of stable materials. Case studies involving automotive tires and macro-/nano-plastics from Northeast Ohio illustrate the efficacy of DART-MS. Additionally, MALDI-MS, another chromatography-free MS method, is discussed for addressing performance issues in complex polyolefin-based materials, offering insights into reaction mechanisms and architectural distributions crucial for process optimization in manufacturing.

Download the agenda here

 

Solving the PFAS challenge: novel targeted and non-targeted workflows on triple quads and ion mobility HRMS
Tuesday, June 4, 2024
7:00 am - 8:00 am

Anaheim Convention Center, 800 W Katella Ave, Anaheim, CA, USA
Room: 210D

PFAS, persistent chemicals used in consumer products since the 1940s, pose significant risks to both humans and the environment due to their persistent, bio-accumulative, and toxic properties. EPA regulations exist to monitor selected PFAS compounds, but the estimated total of 15,000 PFAS compounds, complicates comprehensive analysis. Two workflows are presented: targeted analysis using a highly sensitive triple quadrupole for routine monitoring, exceeding EPA regulations, and a non-targeted approach combining trapped ion mobility spectrometry (TIMS) with UHPLC-HRMS for broader PFAS detection and annotation of unknown PFAS using smart software tools. These methods aim to improve detection capabilities and understanding of PFAS exposure for better public health and environmental protection.

Download the agenda here

 

Rapid and Dynamic Quantitative Screening of Synthetic Cannabinoids with DART-MS Analysis: A Collaborative Case Study
Wednesday, June 5, 2024
7:00 am - 8:00 am

Anaheim Convention Center, 800 W Katella Ave, Anaheim, CA, USA
Room: 210D

Join us for a presentation of a novel rapid and quantitative screening approach for detection and measurement of 16 synthetic cannabinoids using DART-MS. Our novel approach resolves drawbacks associated with traditional immunoassay-based detection, such as cross-reactivity and low sensitivity. Through comparative validation with LC-MS using confirmed positive urine samples, the DART-MS screening method demonstrates high selectivity and accuracy. With a throughput of under 30 seconds per sample, this approach offers a cost-effective and efficient solution for detecting synthetic cannabinoids in urine samples.

Download the agenda here

register here

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Our actitivites at ASMS

eXceed Symposia - June 2, 2024
Breakfast Workshops

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Disclaimer:

As you are certainly aware, special compliance regulations apply to public officials* and healthcare professionals** with regards to the event we are planning. If you accept our invitation, we will therefore assume that you will observe the compliance regulations that apply to you and that you have the necessary employer approval.

*Government Official means according the Bruker policies any of the following: any officer, employee or representative of a government (national, regional or local) entity, or any public agency, public authority, department or instrumentality thereof, regardless of their rank or title (e.g. a regulatory official or government inspector); any person working for or advising a government-owned or government-controlled enterprise (e.g. a professor at a government-owned university, or a purchaser at a government-owned hospital); any person working for or advising a national or international non-governmental organization (e.g. an employee of the Red Cross or The World Bank); any person performing a public function or providing a public service, even if that person works for a non-governmental institution (e.g. private security personnel working in public functions); any person hired to review or accept bids for a government agency; any person with the responsibility to allocate or expend government funds; any person in a public law function, civil servant, judge or military personnel; any person acting for a political party, including party officials, candidates or individuals holding a position in a political party office; members of royal families; or immediate family members of any of the persons listed above. An immediate family member is a grandparent, parent, spouse, significant other, child, or sibling. 

**A Healthcare Professional (HCP) is in accordance with the Bruker policies any physician, dentist, nurse, pharmacist or other individual who may prescribe, administer, purchase, dispense, recommend, or supply medical products or treatments or pharmaceutical products. In many cases, Bruker interacts with HCPs who work for state-owned hospitals (e.g. as medical scientists). These individuals will be classified as both HCPs and Government Officials.

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Thank you for registering for our activities at ASMS! We look forward to seeing you there!

ASMS Posters

ASMS 2024 Posters

MP 017 Rapid Screening and Quantification of PFAS in Contaminated Soil utilizing DART-MS/MS

MP 055 Improved proteome coverage combined with reproducible quantitation on the timsTOF platform

MP 062 Trapped Ion Mobility Separation (TIMS) in Combination with Scanning Quadrupole Isolation for Data Independent Acquisition in Proteomics

MP 142 Direct Analysis of Petroleum and Biofuels with FT-ICR MS and Direct Ionization Probe APPI

MP 174 A novel approach for monitoring multi-classes of POPs in a single run by GC-Ion Mobility-HRMS

MP 228 Royal jelly's phenolic profile via UPLC-VIP-HESI-TIMS-QTOF-MS: A thorough characterization following a multivariate optimization approach

MP 231 Direct Analysis in Real-Time with High Resolution Mass Spectrometry: A Rapid Tool for Black Truffle Authentication

MP 368 A spatial multiomics workflow on a new benchtop MALDI-TOF instrument for deciphering the lipid and expressed protein landscape in tissues

MP 385 How Clean is “Clean”? Going Above and Beyond the Conventional Check-Clean with a Rapid, DART-MS Protocol

MP 403 TIMS-enabled 4D-Metabolomics workflow for the automated analysis of derivatised analytes

MP 436 DeepCCS: Context-aware prediction of peptide collisional cross section increases peptide recovery for out-of-distribution data-independent acquisition (DIA) datasets

MP 469 In-depth investigation of PFAS occurrence in environmental samples combining LC-VIP HESI-TIMS-QTOF MS with PASEF and untargeted data processing

MP 521 Application of TIMS-MRMS to the study of lipids in human blood plasma

MP 523 Paving the way toward analysis of Caenorhabditis elegansindividuality – Development of single worm lipidomics based on nanoLC-TIMS-MS/MS

MP 538 A system suitability scheme for assessment of longitudinal LC-TIMS-MS performance to promote reproducibility in omics sciences

MP 756 Increasing throughput while maintaining coverage depths in single cell proteomics using the timsTOF Ultra

MP 763 Non-small cell Lung cancer single spheroid analysis using the cellenONE with proteoCHIP EVO 96 workflow on the timsTOF Ultra

MP 816 Optimization of Adeno-Associated Virus peptide mapping using trapped ion mobility spectrometry

TP 021 Rapid Quantitative Screening of 18 Synthetic Cannabinoids in Urine Using DART-MS Analysis

TP 086 Detecting PFAS beyond the Current Regulative Request: a Comprehensive Overview of the Contamination in Water by UPHLC-Ion mobility-HRMS

TP 203 Characterization of a new MALDI-TOF axial benchtop instrument for MALDI Imaging applications

TP 359 Analysis of Lipid Nanoparticle Components by MALDI Trapped Ion Mobility Spectrometry

TP 374 Probing the Environmental Fortitude of mRNA Lipid Nanoparticles: A TIMS-TOF Insights into Stress-Induced Degradation

TP 386 Analysis of novel Caenorhabditis elegans-specific phosphorylated sphingolipids using LC-TIMS-MS/MS and MassQL

TP 418 Application of Dried Blood Spot Microsampling for High-Throughput  Four-Dimensional Trapped Ion Mobility Spectrometry Lipidomics

TP 567 Dia-PASEF for in-depth immunopeptidomics analysis: Challenges and new opportunities

TP 583 TIMSrescore: timsTOF-optimized PSM rescoring boosts identification rates for immunopeptidomics

TP 589 Advancing Low input Chromatography: Developing a novel Column for Improved Immunopeptidomics IDs

TP 724 Optimizing LC-MS/MS settings for plasma proteomics analysis with cap-flow LC separation and dia-PASEF

TP 731 Turbocharging Discovery: Crafting a High-Speed, High-Efficiency Monolithic Column for Breakneck Single-Cell Analysis

WP 228 The timsTOF Ultra enables deep global ubiquitinomics of ultra-low protein input samples for validating degrader drug targets

WP 372 Combination of fluorescence and IR images with protein and lipid MALDI Imaging allows more insights into disease phenotypes

WP 417 Significantly faster library-free dia-PASEF analysis with a Spectronaut integrated workflow in ProteoScape

WP 424 Longitudinal data quality monitoring enables improvement of quality management practices: a case study in proteomic research utilizing a digital-twin approach

WP 493 Elevating Precision in Single-Cell Applications: A Breakthrough with Monolithic Silica Capillary Columns

WP 687 Sequence Analysis of Proteins enhanced by TIMS-Enabled Next-Generation MALDI Top-Down Sequencing using a Dedicated Software Workflow

WP 762 dia-PASEF proteomic analysis of HNSCC tumor and stroma enriched sections from FFPE samples prepared with laser capture microdissection

WP 806 Graphical Data Analysis and Sample Comparison of Complex Mesophase Pitches

WP 807 MALDI-TOF MS Analysis of Mechanopolymers and Vitrimers

ThP 090 Dia-PASEF for in-depth immunopeptidomics analysis: Challenges and new opportunities

ThP 420 Strategies for assessing and monitoring consistent quality in MALDI Imaging experiments

ThP 422 Integration and joint multivariate analysis of multimodal chemical imaging data on an example case of hepatocellular carcinoma in rat

ThP 459 prmImaging: an integrated workflow for the analysis and interpretation of spatial on-tissue tandem mass spectrometry of lipids

ThP 460 Deep molecular coverage at faster throughput: IR Guided MALDI Imaging in cancer research

ThP 464 Targeted protein imaging of kidney pathologies using MALDI Imaging

ThP 614 Unleashing High Sensitivity: NanoLC Monolithic Columns in 4D Metabolomics and Lipidomics

ThP 761 Evaluating a new Workflow for Top-Down Protein Sequence Confirmation andde novo Sequencing 

 

For Research Use Only. Not for use in clinical diagnostic procedures.