Benchtop NMR, an emerging tool for high fidelity PAT and QC
04th September 2023, from 10.30 to 13.30 BST
ABCRF, Pharmacy Building, University College Cork
Tailored to the Irish pharmaceutical manufacturing industry, this event will show the results from the evaluation of benchtop NMR spectroscopy by the Analytical & Biological Chemistry Research Facility (ABCRF). We will start with short introductory talks by Dr. Lorraine Bateman, UCC and Dr. Anna Codina, Bruker BioSpin, followed by lunch. During lunch time there will be plenty of time for networking with other leaders and the opportunity to visit the labs where the Fourier RxnLab is up and running. The ABCRF team will share their experiences and honest opinion about the capabilities of this emerging technique, especially for on-line process monitoring and control.
Agenda
| Time (BST) | Title | Speaker |
| 10.30 | Arrival and coffee | |
| 11.00 – 12:00 | Talk ‘Why benchtop NMR for PAT and QC?’ | Dr. Anna Codina |
| Talk: ‘Reaction monitoring at low field.’ | Dr. Lorraine Bateman | |
| 12.00 – 13.30 | Lunch, poster session and show and tell in the lab |
Key Learnings
- Why would we use benchtop NMR for PAT and QC?
- Applications of benchtop NMR. How can benchtop NMR solutions serve manufacturing?
- Results from using benchtop NMR to monitor real reactions. What type of information can we extract?
- Challenges, opportunities and next steps
Speakers
Dr. Lorraine Bateman
Lecturer in Pharmaceutical Chemistry and NMR Spectroscopist, University College CorkDr. Lorraine Bateman obtained her degree in Chemistry & Applied Chemistry from NUI, Galway where she also studied for her PhD, graduating in 2006. Her doctoral research was conducted in the area of chiral diamide ligand synthesis and asymmetric catalysis. She subsequently worked as an industrial research chemist in the area of chiral phosphine ligand synthesis. She joined University College Cork as NMR Spectroscopist at the Analytical and Biological Chemistry Research Facility. In 2014, Lorraine received an SFI Advance Award to pursue independent research in the area of Quantitative NMR Spectroscopy. In 2017, she was appointed as Lecturer in Pharmaceutical Chemistry – a joint appointment between the Schools of Chemistry and Pharmacy.
Dr. Anna Codina
Director Pharmaceutical Business Unit, Bruker BioSpin
Anna has a degree in Chemistry and a PhD in Protein NMR from the University of Barcelona, Spain. She undertook her post-doc in protein NMR at the MRC Laboratory of Molecular Biology in Cambridge, UK, and following that worked in the Analytical R&D department of Pfizer for eight years, becoming proficient in low level impurity structure elucidation, reaction monitoring, qNMR and the preparation of regulatory documentation. She received a Pfizer Worldwide Achievement Award for the implementation of reaction monitoring by NMR in an open access environment.
She joined Bruker in 2011 as Material Characterisation Laboratory Manager and she is now the Director of the Pharmaceutical Business Unit at Bruker BioSpin.
Related Products
Fourier RxnLab
Online monitoring of chemical and bioprocesses by benchtop NMR, in real-time, under process conditions.
