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Fluorescence Microscopy Library

Research Highlight: 
Dr. Guy Nir

Assistant Professor, Department of Biochemistry and Molecular Biology
University of Texas Medical Branch

Exploring Genome Structure and Gene Expression Using Super-Resolution Microscopy

In this research highlight, Dr. Nir discusses his research regarding how genome structures can shape transcriptional regulation in different biological systems, utilizing super-resolution microscopy as a main technology for investigation.

"I was fascinated by how we can use physics as a tool to understand biology. That's what got me started with imaging and being really obsessed about genome structure and how that relates to function. "

Guy Nir, Ph.D., Assistant Professor, Department of Biochemistry and Molecular Biology
University of Texas Medical Branch

ABOUT THE RESEARCHER:

Dr. Guy Nir is an Assistant Professor in the Department of Biochemistry and Molecular Biology at the University of Texas Medical Branch. He is also affiliated with the Department of Neuroscience, Cell Biology, and Anatomy, and is a member of the Sealy Center for Structural Biology and Molecular Biophysics at UTMB.

FIELD OF STUDY:

Dr. Nir’s research program focuses on how genome structures can shape transcriptional regulation in different biological systems, utilizing super-resolution microscopy as a main technology for investigation. His lab studies this phenomenon at the single-cell level, enabling simultaneous detection of gene expression and structure that is critical for determining their relationship.