Microbiology & Diagnostics

Antimicrobial susceptibility testing

The MICRONAUT broth microdilution (BMD) product portfolio offers a broad range of antibiotic resistance and specialty antimicrobial susceptibility testing

MICRONAUT - A broad range of antibiotic resistance and specialty susceptibility testing

Detection of resistance mechanisms and quantification of microbial resistance by determination of true MICs is performed using the MICRONAUT broth microdilution (BMD) product portfolio.

The MICRONAUT products are based on phenotypic detection of resistance as expressed by microbial growth in the presence of antibiotic compounds. The broth microdilution procedure is a standardized method and a worldwide accepted reference system for determination of the MIC.

Development and manufacturing is done by MERLIN Diagnostika GmbH - a Bruker  company since 2017. The products are used in routine laboratories in the field of human medicine as well as in veterinary medicine.

A variety of MICRONAUT products is available for accurate, complete and true MIC determination of microorganisms as well as detection of important resistance mechanisms of Ambler class A (ESBL, KPC), class B (MBL), class C (AMP-C) and class D (OXA-48-like) cephalosporinases and/or carbapenemases.

Additionally your own customized antibiogram, according to your preferred standard like EUCAST or CLSI, can be composed from more than 200 antibiotics. Make your choice, whether it's breakpoint procedure, MIC testing or a combination of both.

The distribution of special customized products for research facilities and industrial multi center studies remains in the responsibility of MERLIN.

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Growth Media

For susceptibility testing of microorganisms
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MICRONAUT IVD System

MICRONAUT IVD system offers a range of antibiotic resistance and specialty susceptibility testing
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Software and Devices

The software and devices available for using the MICRONAUT systems offer users a flexible degree of automation.
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MICRONAUT-AM

The increasing prevalence and severity of fungal infections in healthcare scenarios requires a standardized routine antifungal susceptibility test (AFST) in the microbiology lab. The MICRONAUT-AM system uses MIC plates for the automated or manual susceptibility testing of yeast and cryptococci.
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MICRONAUT-S Anaerobes MIC

Based on the broth microdilution (BMD) procedure, the AST plate MICRONAUT-S Anaerobes MIC provides the tool for phenotypic detection of clinically relevant resistance mechanisms in anaerobic pathogens such as Clostridium spp., Bacteroides spp. and Peptostreptococcus spp.
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MICRONAUT-S MDR MRGN-Screening

Based on the standard broth microdilution (BMD) procedure, the antimicrobial susceptibility testing (AST) plate MICRONAUT-S MDR MRGN Screening provides the phenotypic detection of clinically relevant resistance mechanisms, including confirmation of cephalosporinases and carbapenemases in Enterobacterales and non-fermenters.
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MICRONAUT-S MRSA GP

Based on the broth microdilution (BMD) procedure, the MICRONAUT-S MRSA/GP system provides the phenotypic detection of clinically relevant single or multi-resistance in staphylococci, enterococci and streptococci organisms. The susceptibility testing with highly effective back up antibiotics like ceftaroline, linezolid, tigecycline, daptomycin, and vancomycin offers therapeutic options in case of multi-drug resistance.
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MICRONAUT-S Pneumococci & Haemophilus MIC

Based on the standard broth microdilution (BMD) method, the routine antimicrobial susceptibility testing (AST) plate MICRONAUT-S Pneumococcus & Haemophilus MIC provides the phenotypic quantification of MIC values for 14 different antibiotics and antibiotic combinations commonly used for treatment of infections caused by Streptococcus pneumoniae and Haemophilus influenzae.
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MICRONAUT-S ß-Lactamases & MICRONAUT-S Carbapenemases Detection

Based on the standard broth microdilution (BMD) method, the MICRONAUT-S ß-Lactamases and MICRONAUT-S Carbapenemases Detection systems are the only broth microdilution based systems that can differentiate between all Ambler class A (ESBL, KPC), class B (MBL), class C (AMP-C) and class D (OXA-48-like) cephalosporinases and / or carbapenemases.
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MICRONAUT-S Pseudomonas MIC

Based on the standard broth microdilution (BMD) method, the antimicrobial susceptibility testing (AST) plate MICRONAUT-S Pseudomonas MIC provides the phenotypic quantification of MIC values for critically important antibiotics and back up antibiotics used for treatment of infections caused by non-fermenting pathogens like Pseudomonas aeruginosa, Acinetobacter baumannii, and Stenotrophomonas maltophilia.
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MICRONAUT-VET

MICRONAUT VET System is based on the broth microdilution (BMD) procedure, the reference for AST, and provides species-specific true MIC values for a broad spectrum of veterinary-specific antibiotics.