Ultra-high resolution LC-QTOF MS

impact II

Analytical performance for trace analysis in complex matrices

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One run for qual and quant

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Ultra-High resolution LC-QTOF MS

Screen residues and contaminants, identify impurities

Performance
Full sensitivity resolution (FSR) of > 60,000 • Dual ion funnel • ESI and HESI Sources • GC-APCI Source • Collision cell with broad mass transfer.
High-definition
Five orders of magnitude dynamic range achieved at UHPLC speeds due to 50 GBit/sec sampling technology-definitive trace analysis from complex, high-background matrices.
Plug and play
One-shot acquisition with triple-quadrupole sensitivity ensuring qualitative and quantitative results in one LC run with fastest time-to-success.
Instant expertise
Intelligent self-optimizing MS/MS routines to step forward from routine only.

Características

impact II

Enabling chromatography

Even outstanding mass spectrometers benefit from good chromatography. By choosing the impact II, hyphenation is made easy with

  • UHPLC
  • GC
  • CE or
  • IC

Switching from one modality to another takes less than 10 minutes each.

Fast methods offer additional flexibility and do not necessarily require a chromatographic device. The Direct Insertion Probe serves best.

Beneficios

impact II

Instant expertise in accurate mass LC-MS/MS

Research-grade technology applied to every routine analytical task. The Bruker impact II QTOF features:

  • Low picogram sensitivity while delivering, highly precise MS and MS/MS data
  • Definitive trace analysis from complex, high-background matrices, by increased dynamic range
  • True Isotopic Pattern for unambiguous spectra
  • Superior 1 ppm mass accuracy ensured by automated calibration
  • 50 GBit/sec sampling technology maintaining full specification resolution even during ultrafast chromatography
 

The impact II combines the robustness of Bruker orthogonal Time-of-Flight instruments with 10-bit digitizer technology that allows for compound detection and identification across an unrivalled dynamic range.

Aplicaciones

impact II

Achieve your goals in a range of applications

  • Synthetic chemistry support
  • Forensics and doping control
  • Drug metabolite, degradant and impurity identification and quantitation
  • Biomarker discovery and validation in proteomics and metabolomics
  • Intact protein analysis and characterization of biopharmaceuticals
High-performance OMICS
High performance proteomics and metabolomics studies using the impact II QTOF provide insight into how rational strain design increased bio-production efficiency. The Bruker impact II QTOF system is well suited to bottom-up proteomic and metabolomic workflows, and can be used to map the results of both metabolic and proteomic changes onto biochemical pathways.

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