Polysaccharide-protein conjugate vaccines are among the safest and most successful vaccines developed during the last 30 years. Since the first semisynthetic chemical conjugate vaccine licensed in the 1980’s to protect human against Haemophilus influenzae type b infection, conjugate vaccines against Neisseria meningitidis and Streptococcus pneumoniae have been developed and registered using the same approach (i.e. bacterial growth to produce capsular polysaccharide antigen and chemical coupling to carrier protein).
Dr. Ian Clegg
Regional Market Manager Bruker
Dr. Francesco Berti
Scientific Director, Technical R&D GSK Vaccines